Protein Alignment DAAM and LOC100148950

DIOPT Version :10

• Sequence 1: NP_001188522.1
• Gene: DAAM / 31075
• FlyBaseID: FBgn0025641
• Length: 1463
• Species: Drosophila melanogaster
• Sequence 2: NP_001430265.1
• Gene: LOC100148950 / 100148950
• -ID: -
• Length: 1183
• Species: Danio rerio
• Alignment Length: 1057
• Identity: 228/1057 - (21%)
• Similarity: 399/1057 - (37%)
• Gaps: 312/1057 - (29%)

  Fly   560 MLH--FQVFATERTRFQSIVNDLDRSTYAYRDNVNLKTALMSFVN---------AVLNYGPGQEN 613
            |.|  :.|.|..|: |.:.:::|:.....|...:......:...|         :.::|...|.|
Zfish   167 MAHDGWDVMAEPRS-FDAELSELENLYLEYEKPLGNTRGGVQITNNTQQTDGNTSSVHYREDQIN 230

  Fly   614 LEFRLHLRYEFLMLGIQPVIDKLRTHENETLDRHLDFFEMVRAEDEKEFARRFKEEHVD----TK 674
               |..|:|    ..::|| ...|.||.||..:|                  |.:||.:    .|
Zfish   231 ---RRDLQY----ANVKPV-SCARLHEGETEAKH------------------FPKEHCEGSPNNK 269

  Fly   675 SAGSMFELLRRKLSHSP-----------AYP-----HMLSLLQHMLLLPYTGH------------ 711
            |:..      |..|.||           :||     ..:|.|...|..|...|
Zfish   270 SSNV------RSWSRSPTSSSLSSVFNVSYPQTNTLQSMSPLSSQLPSPQMNHRIVMLPEDDDDE 328

  Fly   712 -------C-TEHWLLIDRVV------QQIVLQVEQRPNSDLIVDPDD---------PEKQLKLAA 753
                   | :|:.|.:...|      ::.|.::|.|.:..|.|:...         ||....|..
Zfish   329 DDDGNKRCFSENQLKVSSEVIDKNGNRRSVTRLELRLSGSLAVNGASTSSENSLLRPEDIWMLDG 393

  Fly   754 ESPV-HDPDVAPLQIDVAKLVRLLVKEEQL-------------TQARKRADELERENFDVQS--- 801
            |..: .:|...|.:.|....:|:...|:.:             ::....:|..:|....:|:
Zfish   394 EDSITQEPLCRPSRPDHLDFLRITPPEDDIIGDTPYYPRLGITSEVTSPSDGEDRTPGRLQAVWP 458

  Fly   802 ------------RLAKKEQE---LDLRMQEKEDLETGLARMRERLEKESAQHSQAVQRAQT--AE 849
                        |..:.|.:   |.|:.:.||:||...|....|:.:...:|::.|.|.::  :.
Zfish   459 PPKEAAEEKVGLRYTEAEHQAALLQLKRESKEELEKLQADFELRIFQVRGEHAETVSRLESIISG 523

  Fly   850 MRAEDLQHRLISEQQERARLERL---------------------------VTEG----------- 876
            |:.:.:||.:    |||..|..:                           ..||
Zfish   524 MQQQQVQHPV----QERGELHEVCVSTEDDLPPRSFRNVCVQTDRETFIKTPEGEEPRPALNSSA 584

  Fly   877 -------------------------------------------------------------SIPD 880
                                                                         |:|.
Zfish   585 SLPKKLNLDSISMSLGVALPTPPPLPGSSAPPPPPLPGVAHAPPPPPPLPGAPPPPPLPGSSVPP 649

  Fly   881 DQKVAGLTGC-------NGAVSPPPAPPMLKAIPPPPPPMA--PSMMPPPPPP--CPGAPPPPPS 934
            ...:.|:...       .||..|||.||.|...||||||:.  |...||||||  .||||||||.
Zfish   650 PPPLPGVAHAPPPPPPLPGAPPPPPPPPGLPGAPPPPPPLPGFPGAPPPPPPPPGLPGAPPPPPG 714

  Fly   935 MAQTMAPAPPKV----------DLPKKNVPQPTNPLKSFNWSKLPDAKLQ----GTVWSELDESK 985
            :.....|.||..          ..|:|...:|..|:|...|:::   ::|    .|:||.|:|..
Zfish   715 LPGAPPPPPPAFGGFGFGQVAEKAPRKPAVEPACPMKPLYWNRI---QIQDNNNNTLWSSLEEPD 776

  Fly   986 LYNNMELESIDKLFS----AYQKNGVSATDGSYEDLRVTGKAAKQKVLSVIDGRRAQNCTILLSK 1046
            :.|..|.|   :|||    ..:|..:|.|   ||.     |...:|::.::||:|:|...||:|.
Zfish   777 IINTTEFE---ELFSKANLQAKKKPLSDT---YEK-----KNKAKKIIKLLDGKRSQAVGILISS 830

  Fly  1047 LKMSDMEISKAILSMDSNEQLQLDMVEQLLKFTPSAEERALLDEHSE-----DIESLARADRFLY 1106
            |.:...:|.:|:|::| :..:.|:.:|.|.:.....:|...:.:|.|     :::.|.:.::|||
Zfish   831 LHLEMKDIQQAVLTVD-HSVVDLETIEALYENRAQPDELEKIKKHYESSKEDELKLLDKPEQFLY 894

  Fly  1107 EISKIPHYEQRLKSLHYKKRFMLTINDLVPRITSVMEASREVARSRRLRKLLELVLALGNYMNRG 1171
            |:|:||.:..|...:.::..|:.:|:.:..::..:....:....:..::.::.::||.|||||.|
Zfish   895 ELSQIPDFAGRSHCIIFQSVFVDSISSVRRKVEIISTVCKVFLDNDSVKDVIGVILAFGNYMNGG 959

  Fly  1172 --ARGNASGFRLASLNRLADTKSSAAKGTTLLHYLVQVIERKF-------KDLLKLED--DIPHV 1225
              .||.|.||.|..|.:|.|.||...: .:|:.|:|....|..       |.:..|.:  |:.|
Zfish   960 NRTRGQADGFGLEILPKLKDVKSRDNR-MSLVDYVVSYYLRNMDENAGTDKSVFPLPEPQDLFH- 1022

  Fly  1226 REASKVSLGEMDKDIQMLRTGLADVAREIEFHRSSGPAQQGDRFLPVMREFHAQASVRFAELEDK 1290
              |::|...::.||::.|:..|....:|::....:...:....|...|..|.:.|...:...:::
Zfish  1023 --AAQVKFEDLAKDLRKLKKELTACVKEVQQVCENSSDEHLQPFKDKMETFISTAQAEYTSEDER 1085

  Fly  1291 FQDMKTRFDRAVRLFG---EDG-SVLQPDEFFGIFDSFLAAFAEARHDNESFRRRQEEEEKRAKQ 1351
            .|..:..|.:.|..||   :.| ..:.|:..|.::..|.:.|      ..::.|..:...|...:
Zfish  1086 LQAAQKSFQQMVTYFGLKPKSGEKEVSPNYIFMLWYEFCSDF------KNTWNRESKNISKERLK 1144

  Fly  1352 EAE--LKKRTIERKNKT 1366
            ||:  ::|.|.|:|.:|
Zfish  1145 EAQQTVQKITAEKKVET 1161

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DAAM	NP_001188522.1	Drf_GBD	349..548	CDD:461886
		Drf_FH3	551..737	CDD:461885	46/233 (20%)
		Smc	<765..>875	CDD:440809	26/169 (15%)
		FH2	950..1328	CDD:396655	100/405 (25%)
LOC100148950	NP_001430265.1	None