Protein Alignment DAAM and diaph3

DIOPT Version :9

• Sequence 1: NP_001188522.1
• Gene: DAAM / 31075
• FlyBaseID: FBgn0025641
• Length: 1463
• Species: Drosophila melanogaster
• Sequence 2: XP_031752973.1
• Gene: diaph3 / 100145568
• XenbaseID: XB-GENE-868499
• Length: 1162
• Species: Xenopus tropicalis
• Alignment Length: 1259
• Identity: 322/1259 - (25%)
• Similarity: 542/1259 - (43%)
• Gaps: 260/1259 - (20%)

  Fly   310 KMPGFRGRRVWCGCFK--------------DDEPPEICVVEGAFTLQTLTPTQPMPSVDELDTKF 360
            ::||.:..|.:....|              ||.|.           :.|:..:.:|       .|
 Frog    54 RIPGSKKERPYLNNMKSSSTSSEWGVPSEYDDYPS-----------KQLSEKEVLP-------LF 100

  Fly   361 AELVEELDLTAPNKEAMLSLPAQKKWQIYCSRKLPLDAADGPDAAAVTQPPTAEHYI---ERLKE 422
            .:::|:::|   |:|                :|.||...|     ..|:......||   .:...
 Frog   101 EKMMEDMNL---NEE----------------KKAPLREKD-----FATKKEMVLQYISTASKAGS 141

  Fly   423 LVVHISLSPEDSPSHEL--GNRLDGHAAFVDALKTALRTSTHSFVLRFVELDGLPALLDLLLQLD 485
            |.....:||::. .|||  |...:...:::|:|:.:|.::..|:|..|.. |||..|||:|
 Frog   142 LRSSRQISPQEF-IHELKSGAADERLVSYLDSLRVSLTSNPVSWVESFGH-DGLGLLLDIL---- 200

  Fly   486 IRVANSP--------LHTSLIGCIKALMNNSMGRAHVLAHPTAIDTIARSLAADNIRTKIAALEI 542
            .|:.|..        :....|.|:||.|||..|...:|....::..:|:::...........:::
 Frog   201 ERMVNGKRTEKIEKRIQHKAIQCLKAFMNNKYGLERILGEERSLSLLAKAMDPKQANMMTDVVKL 265

  Fly   543 LGAVCLVPGGHRKVLQAMLHFQVFATER---TRFQSIVNDLDRSTYAYRDNVNLKTALMSFVNAV 604
            |.|:|:|  |....|:.:|.....|.|.   .||..||..|      :.:.:.|:.|.|..:||:
 Frog   266 LSAICIV--GEENTLEKVLEAITAAAEERGIIRFSPIVGGL------HHNLIQLQVACMQLINAL 322

  Fly   605 LNYGPGQENLEFRLHLRYEFLMLGIQPVIDKLRTHENETLDRHLDFFEMVRAEDEKEFARRFKEE 669
            :.   ..::|:||||:|.||:..|::.::.:|:..:|:.||..|..||..:.||..||:.|..:.
 Frog   323 VT---SPDDLDFRLHIRNEFMRSGLKEILPQLKHVKNDALDIQLRVFEEHKEEDMIEFSHRLDDI 384

  Fly   670 HVDTKSAGSMFELLRRKLSHSPAYPHMLSLLQHMLLL--PYTGHCTEHWLLIDRVVQQIVLQVEQ 732
            ..:...|..:|.::...:..:.|..:.||:|||:||:  .|... .:::.:|:..:.||||....
 Frog   385 RSEMDDASDVFNMVWNSVRDTNAEGYFLSILQHLLLIRNDYFAK-PQYFKIIEESISQIVLHRSG 448

  Fly   733 RPNSDLIVDPDDPEKQLKLAAESPVHDPDVAPLQIDVAKLVRLLVKEEQLTQARKRADELERENF 797
                   :|||...::               .|.:|.:.|:.:.:.       :.:.:|.|...|
 Frog   449 -------IDPDFTYRK---------------RLDVDFSYLLDVCID-------KAKTEEFEERFF 484

  Fly   798 DVQSRLAKKEQELDLRMQEKEDLETGLARMRE---RLEKESAQHSQAVQRAQTAEMRAEDLQHRL 859
            ::..   |.|:|..:|.:.:..|:....::.|   .|:...:|:..|:
 Frog   485 EMSK---KYEEEFTIRQEAQSQLQKNEEKINELQAELQAFKSQYGAAI----------------- 529

  Fly   860 ISEQQERARLERLVTEGSIPDD---QKVAGLTGCNGAVSPPPAPPMLKAIPPPPPPMAPSMMPPP 921
                         |..||:|.|   .|.:.:     ...|||.||.....||||||      |||
 Frog   530 -------------VVPGSVPGDAASNKTSSI-----VPKPPPVPPCGLVPPPPPPP------PPP 570

  Fly   922 PPPCPGAPPPPPSMAQTMAPAPP-----KVDLPKKNVPQPTNPLKSF---------NWSKL-PDA 971
            |||..|:.||        ||.||     |:..|.:::|....|.|.|         ||.|: |:.
 Frog   571 PPPLFGSAPP--------APPPPGFGNGKLFPPMQSLPFGLKPKKEFKPEVVMKRLNWQKITPNE 627

  Fly   972 KLQGTVWSELDESKLYNNMEL-ESIDKLFSAYQKNGVSATDGSYEDLRVTGKAAKQKVLSVIDGR 1035
            ..:...|....|.. |.:.|| ..::..||..:|......|.:.|:.....|..|:  |.|::.:
 Frog   628 MTESCFWLTAKEEG-YEDKELFFQLENTFSCQRKAVEVVKDDAAEEKMAIKKRIKE--LKVLEPK 689

  Fly  1036 RAQNCTILLSKLKMSDMEISKAILSMDSNEQLQLDMVEQLLKFTPSAEERALLDEHSEDIESLAR 1100
            .|||.:|.|...::...||.|.||.:|.. ||...||:.|:|..|:..:...|.....:..||:.
 Frog   690 IAQNLSIFLGSYRLPYEEIKKIILEIDET-QLSESMVQNLIKNMPAQTQLNSLANLKSEYLSLSE 753

  Fly  1101 ADRFLYEISKIPHYEQRLKSLHYKKRFMLTINDLVPRITSVMEASREVARSRRLRKLLELVLALG 1165
            .::|...:|.:.....||.::.::.:|...:|::.|.|.:|.||..|:.:|:...||||:||.:|
 Frog   754 PEQFGVVMSSVKKLIPRLNAILFRLQFEEQVNNIKPDIMAVSEACEEIKKSKSFGKLLEIVLLIG 818

  Fly  1166 NYMNRGARGNAS--GFRLASLNRLADTKSSAAKGTTLLHYLVQVIERKFKDLLKLEDDIPHVREA 1228
            ||||.|:| ||.  ||.|:||.:|.||| ||.:.|||||:|..:.:::|.|:....:|:..|.:|
 Frog   819 NYMNAGSR-NAQTFGFCLSSLCKLKDTK-SADQNTTLLHFLADICDKRFPDIKIFVEDVQTVDKA 881

  Fly  1229 SKVSLGEMDKDIQMLRTGLADVAREIEFHRSSGPAQQGDRFLPVMREFHAQASVRFAELEDKFQD 1293
            ||||...::|.::.:...|..:.:::|....|..|.  |:|:..|..|...|..:|.:|...:::
 Frog   882 SKVSAENLEKTMKQMERQLQQLEKDLETFPLSDDAH--DKFVTKMSGFAVYAREQFKKLSRMYEN 944

  Fly  1294 MKTRFDRAVRLFGEDGSVLQPDEFFGIFDSFLAAFAEARHDNESFRRRQ-EEEEKRAKQ------ 1351
            |...:...:..:..|...:..:|||...::|...|.:|  ..|:.||:: ||::||.||
 Frog   945 MDKLYQGLMEYYVLDSKKVSVEEFFTDVNNFRTMFMQA--SKENIRRKEAEEKQKRVKQAKEMAE 1007

  Fly  1352 ----EAELKKRTIERKNKTGLMTSVARNL--GLKSGSSNGDPDSPAKGGDNKGEFDDLISALRTG 1410
                |.:|||:.:..||:.|..|.|..:|  .|:||::..|   ..|......::.:.||.....
 Frog  1008 KEKLERQLKKKRLLEKNREGEETGVMDSLLEALQSGAAFRD---RRKRTPRPKDWHENISPSSER 1069

  Fly  1411 DV-----FGEDMAKFKRSRK-------------ARVLN----GGGSSTG---------------H 1438
            .|     :.....:|:|||.             |:.||    ...||.|               .
 Frog  1070 PVLKSRNYENQKPQFERSRSRPNIHSNSTRAPVAKELNYEMETHSSSKGSKVISRKEACNAEINR 1134

  Fly  1439 TSPPRHGSLQREESGRERERTVRR 1462
            ...|.|||..:.||..|.|..:.|
 Frog  1135 EKAPGHGSAAKAESIPEVEALLAR 1158

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DAAM	NP_001188522.1	Drf_GBD	349..548	CDD:283920	47/211 (22%)
		Drf_FH3	551..737	CDD:283917	52/190 (27%)
		FliJ	779..>875	CDD:280262	13/98 (13%)
		FH2	950..1328	CDD:280362	115/390 (29%)
diaph3	XP_031752973.1	Drf_GBD	89..271	CDD:399398	48/218 (22%)
		Drf_FH3	279..466	CDD:368862	55/218 (25%)
		FH2	605..979	CDD:396655	114/381 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1204639at2759
OrthoFinder	1	1.000	-	-		FOG0000085
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920