DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32812 and RCVRN

DIOPT Version :9

Sequence 1:	NP_001284770.1	Gene:	CG32812 / 31074	FlyBaseID:	FBgn0025642	Length:	225	Species:	Drosophila melanogaster
Sequence 2:	NP_002894.1	Gene:	RCVRN / 5957	HGNCID:	9937	Length:	200	Species:	Homo sapiens

Alignment Length:	174	Identity:	39/174 - (22%)
Similarity:	66/174 - (37%)	Gaps:	46/174 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 HQQATGLSAEQLE--QLHTRF--RSLDRHQRGYLTPTDLLRIPQLSLNPLHRQIIDGFFPSRDPS 77
            :.::..||.|.||  ||:|:|  ..|....:.:|......||.|.....::.:    |||..||.
Human     3 NSKSGALSKEILEELQLNTKFSEEELCSWYQSFLKDCPTGRITQQQFQSIYAK----FFPDTDPK 63

  Fly    78 A---------------RIGFKQFVDTCSTILVPQFGRGSVRRRDGRVQKLQLLSKMFDTRRSGCI 127
            |               .:.||::|     |.:.....|...      |||:....::|...:|.|
Human    64 AYAQHVFRSFDSNLDGTLDFKEYV-----IALHMTTAGKTN------QKLEWAFSLYDVDGNGTI 117

  Fly   128 TRSDFRQIMRSIVNLAWSQQ----QDQERQEGLSENRLPEVEAE 167
            ::::..:|:.:|..:...:.    .|.|        ..||..||
Human   118 SKNEVLEIVMAIFKMITPEDVKLLPDDE--------NTPEKRAE 153

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32812	NP_001284770.1	EF-hand_7	31..136	CDD:290234	25/121 (21%)
CG32812	NP_001284770.1	EF-hand_6	117..139	CDD:290141	4/21 (19%)
RCVRN	NP_002894.1	FRQ1	14..182	CDD:227455	36/163 (22%)
RCVRN	NP_002894.1	Interaction with GRK1. /evidence=ECO:0000250\|UniProtKB:P21457	189..192
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1271942at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920