DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32812 and KCNIP2

DIOPT Version :9

Sequence 1:	NP_001284770.1	Gene:	CG32812 / 31074	FlyBaseID:	FBgn0025642	Length:	225	Species:	Drosophila melanogaster
Sequence 2:	NP_055406.2	Gene:	KCNIP2 / 30819	HGNCID:	15522	Length:	285	Species:	Homo sapiens

Alignment Length:	194	Identity:	49/194 - (25%)
Similarity:	77/194 - (39%)	Gaps:	44/194 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 RQLNPVQLCDHQQATGL--SAEQLEQL--HTRF--RSLDRHQRGYLT--PTDLLRIPQLSLNPLH 63
            |.|:|..:.|..:.:.:  ..|.||||  .|:|  :.|....||:..  |:.::.....
Human    85 RLLDPDSVDDEFELSTVCHRPEGLEQLQEQTKFTRKELQVLYRGFKNECPSGIVNEENF------ 143

  Fly    64 RQIIDGFFPSRDPS---------------ARIGFKQFVDTCSTILVPQFGRGSVRRRDGRVQKLQ 113
            :||...|||..|.|               ..:.|:.||...|.||     ||:|..|      |.
Human   144 KQIYSQFFPQGDSSTYATFLFNAFDTNHDGSVSFEDFVAGLSVIL-----RGTVDDR------LN 197

  Fly   114 LLSKMFDTRRSGCITRSDFRQIMRSIVNLAWSQQQDQERQEGLSENRLPEVEAELQLLEHQAFG 177
            ....::|..:.||||:.:...||:||.::.........|:|...|:    ||:..|.::....|
Human   198 WAFNLYDLNKDGCITKEEMLDIMKSIYDMMGKYTYPALREEAPREH----VESFFQKMDRNKDG 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32812	NP_001284770.1	EF-hand_7	31..136	CDD:290234	30/125 (24%)
CG32812	NP_001284770.1	EF-hand_6	117..139	CDD:290141	7/21 (33%)
KCNIP2	NP_055406.2	FRQ1	108..274	CDD:227455	44/171 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1271942at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920