DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG32812 and CIB3

DIOPT Version :9

Sequence 1:NP_001284770.1 Gene:CG32812 / 31074 FlyBaseID:FBgn0025642 Length:225 Species:Drosophila melanogaster
Sequence 2:NP_473454.1 Gene:CIB3 / 117286 HGNCID:24580 Length:187 Species:Homo sapiens


Alignment Length:219 Identity:48/219 - (21%)
Similarity:77/219 - (35%) Gaps:64/219 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 VGSRQ--LNPVQLCDHQQATGLSAEQLEQLHTRFRSLDRH--QRGYLT------PTDLL-RIPQL 57
            :|::|  ....||..:|..|..:.:::.:|..|::.|...  ...|.|      |.:|: .:|:|
Human     1 MGNKQTVFTHEQLEAYQDCTFFTRKEIMRLFYRYQDLAPQLVPLDYTTCPDVKVPYELIGSMPEL 65

  Fly    58 SLNPLHRQIIDGFFPSRDPSARIGFKQFVDTCSTI--LVPQFGRGSVRRRDGRVQKLQLLSKMFD 120
            ..||..::|...|  |.|....:....|:|..|.:  :.|            |..|.....|::|
Human    66 KDNPFRQRIAQVF--SEDGDGHMTLDNFLDMFSVMSEMAP------------RDLKAYYAFKIYD 116

  Fly   121 TRRSGCITRSDFRQIMRSIVNLAWSQQQDQERQEGLSENRLPEVEAELQLLEHQAFGFCCDHISY 185
            ......|...|..|.:..:.            :.|||..   ||....:.:..:|.|   ||   
Human   117 FNNDDYICAWDLEQTVTKLT------------RGGLSAE---EVSLVCEKVLDEADG---DH--- 160

  Fly   186 GEFEKRLFSVDVDRRLSIAKWLED 209
                        |.|||    |||
Human   161 ------------DGRLS----LED 168

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG32812NP_001284770.1 EF-hand_7 31..136 CDD:290234 26/115 (23%)
EF-hand_6 117..139 CDD:290141 5/21 (24%)
CIB3NP_473454.1 FRQ1 20..178 CDD:227455 43/200 (22%)
EFh 111..173 CDD:238008 21/95 (22%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165156540
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1271942at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.850

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