Protein Alignment CG11403 and dinG

DIOPT Version :10

• Sequence 1: NP_569898.1
• Gene: CG11403 / 31072
• FlyBaseID: FBgn0026876
• Length: 861
• Species: Drosophila melanogaster
• Sequence 2: NP_415320.1
• Gene: dinG / 945431
• ECOCYCID: EG11357
• Length: 716
• Species: Escherichia coli
• Alignment Length: 727
• Identity: 149/727 - (20%)
• Similarity: 263/727 - (36%)
• Gaps: 178/727 - (24%)

  Fly    22 YSPYEIQEQLMQELFQVL--ERGQVGIFESPTGTGKSLTLTCGALTWLARHEELVRTEMLARIRG 84
            :.|...|.|::.::.:.|  |.|:....|:|||.||:|:.....:. :||.|:.......|.:..
E. coli    25 FIPRAPQRQMIADVAKTLAGEEGRHLAIEAPTGVGKTLSYLIPGIA-IAREEQKTLVVSTANVAL 88

  Fly    85 VEQELAK---LKEESEQSSNWLESQGKSR--------AQRAELLRLQHLQALLD------KQEQQ 132
            .:|..:|   |.::......:..:.|:.|        |..:.....|.|.|.||      .||:|
E. coli    89 QDQIYSKDLPLLKKIIPDLKFTAAFGRGRYVCPRNLTALASTEPTQQDLLAFLDDELTPNNQEEQ 153

  Fly   133 LDQIRKGAKKHKRQGRVHPGKLEELEKDLDPESDSDSEHETADGPQEAAEDR---YRPVQIFFCS 194
                   .:..|.:|.:...|.:.|....|...|.|.....:..........   ||... ||.:
E. coli   154 -------KRCAKLKGDLDTYKWDGLRDHTDIAIDDDLWRRLSTDKASCLNRNCYYYRECP-FFVA 210

  Fly   195 RTHSQLAQIVAELRKTPHGQSVRSISLGSRQQLCGNPAVRKL-------KHVGLMNERCLDMATK 252
            |...|.|::|.         :..::.:.:.:.....|..:.|       .|:..:....|:|:.:
E. coli   211 RREIQEAEVVV---------ANHALVMAAMESEAVLPDPKNLLLVLDEGHHLPDVARDALEMSAE 266

  Fly   253 KARPNPSKKSRLTAEANSRCPFKAASLVESLRDLALTEPLDIEELANEGTACGGCSYYASRSAVE 317
            ...|    ..||..:..::.   .|:.:|..|...: .||.|.|..|                 .
E. coli   267 ITAP----WYRLQLDLFTKL---VATCMEQFRPKTI-PPLAIPERLN-----------------A 306

  Fly   318 HAQLILLPYQLLLQKSARNQLGISLKGSIVIVDEAHN------LLDSVAQLHGSEISRQQLERAK 376
            |.:.:   |:|:  .|..|.|.:.:...    .||.:      |.|.|.::      .|:|.:..
E. coli   307 HCEEL---YELI--ASLNNILNLYMPAG----QEAEHRFAMGELPDEVLEI------CQRLAKLT 356

  Fly   377 VQISGYKDHFQKRFTTK----NLLKINQIIFIIRRLLKILDQRKEL-------QSNGCSMMR--T 428
            ..:.|..:.|....:.|    ::::::::|..:.|.|.:.:.:.:|       ||:|..:.:  |
E. coli   357 EMLRGLAELFLNDLSEKTGSHDIVRLHRLILQMNRALGMFEAQSKLWRLASLAQSSGAPVTKWAT 421

  Fly   429 YELTAEGDFFNIDLCELLDFCARTRFARKVQGRADRMEREPRPSENQAPVSTA--RSL-ILQRLA 490
            .| ..||..      .|...|...|.       :|::||....|.....|::|  ||| ...||.
E. coli   422 RE-EREGQL------HLWFHCVGIRV-------SDQLERLLWRSIPHIIVTSATLRSLNSFSRLQ 472

  Fly   491 SEQKLKEKT-----------------KSV--KRRVE-DINKEDKAEELQEQQKPTKKPVEE---- 531
            ....||||.                 |.|  :.||| .|:.|:  :.:.|.....:|.||.
E. coli   473 EMSGLKEKAGDRFVALDSPFNHCEQGKIVIPRMRVEPSIDNEE--QHIAEMAAFFRKQVESKKHL 535

  Fly   532 ---VAPSPIRPLLAFLETLTSNAEDGRILVDPVGGTLKYILLDPAEQFADIVAEARAIVIAGGTM 593
               |..:..|.:..||:.:|    |.|:::...|...:|.|:   |.....||.....|:.|  :
E. coli   536 GMLVLFASGRAMQRFLDYVT----DLRLMLLVQGDQPRYRLV---ELHRKRVANGERSVLVG--L 591

  Fly   594 QPTKE---LKEQLFTGCHDRLVERFYNHVVANDAI-LPFVISNGP-----SGAPLSFKFAHRGSA 649
            |...|   ||..|.:..|        .|.:|...| .|.||:.|.     :..|...:.....|.
E. coli   592 QSFAEGLDLKGDLLSQVH--------IHKIAFPPIDSPVVITEGEWLKSLNRYPFEVQSLPSASF 648

  Fly   650 EMLRELSMILRN 661
            .:::::..::|:
E. coli   649 NLIQQVGRLIRS 660

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11403	NP_569898.1	DEAD-like_helicase_N	42..>101	CDD:475120	15/61 (25%)
		rad3	187..837	CDD:273169	109/540 (20%)
dinG	NP_415320.1	dinG	2..696	CDD:236966	149/727 (20%)