Protein Alignment CG11403 and RAD3

DIOPT Version :10

• Sequence 1: NP_569898.1
• Gene: CG11403 / 31072
• FlyBaseID: FBgn0026876
• Length: 861
• Species: Drosophila melanogaster
• Sequence 2: NP_011098.3
• Gene: RAD3 / 856918
• SGDID: S000000973
• Length: 778
• Species: Saccharomyces cerevisiae
• Alignment Length: 769
• Identity: 176/769 - (22%)
• Similarity: 320/769 - (41%)
• Gaps: 154/769 - (20%)

  Fly   148 RVHPGKLE---ELEKDLDPESDSDSEHETADGPQEA------AEDRYRPV--QIFFCSRTHSQLA 201
            :::|.:..   :::|.||...:|..|..:..|...:      |...:.|.  :|.:||||.|::.
Yeast    16 KIYPEQYNYMCDIKKTLDVGGNSILEMPSGTGKTVSLLSLTIAYQMHYPEHRKIIYCSRTMSEIE 80

  Fly   202 QIVAEL--------RKTPHGQSVRSISLGSRQQLCGNPAVRKLKHVGLMNERCLDMATKKARPNP 258
            :.:.||        ::..:.:..|.:.|.||:.||.:|.|.|.:...:::|:|..|...:|:
Yeast    81 KALVELENLMDYRTKELGYQEDFRGLGLTSRKNLCLHPEVSKERKGTVVDEKCRRMTNGQAK--- 142

  Fly   259 SKKSRLTAEAN-SRCPFKAASLVESLRDLALTEPL-----DIEEL---ANEGTACGGCSYYASRS 314
             :|.....||| ..|.:.     |:|.::.:.:.|     ..|:|   ..|.|.   |.|:..|.
Yeast   143 -RKLEEDPEANVELCEYH-----ENLYNIEVEDYLPKGVFSFEKLLKYCEEKTL---CPYFIVRR 198

  Fly   315 AVEHAQLILLPYQLLLQKSARNQLGISL-KGSIVIVDEAHNLLDSVAQLHGSEISRQQLERAKVQ 378
            .:....:|:..|..||......::...: |.||||.|||||:.:...:....:::...|.||
Yeast   199 MISLCNIIIYSYHYLLDPKIAERVSNEVSKDSIVIFDEAHNIDNVCIESLSLDLTTDALRRA--- 260

  Fly   379 ISGYKDHFQKRFTTKNLLKINQIIFIIRRLLKILDQRKELQSNGCSMMRTYELTAEGDFFNIDLC 443
                         |:....:::.|..:|:                                :|..
Yeast   261 -------------TRGANALDERISEVRK--------------------------------VDSQ 280

  Fly   444 ELLDFCARTRFARKVQG--RADRMEREPRPSENQAPVSTARSLILQRLASEQKLKEKTKS-VKRR 505
            :|.|     .:.:.|||  .||.:..:..|.. :.|| ..:.|:.:.:....:..|...| :||.
Yeast   281 KLQD-----EYEKLVQGLHSADILTDQEEPFV-ETPV-LPQDLLTEAIPGNIRRAEHFVSFLKRL 338

  Fly   506 VE---------DINKEDKAEELQEQQKPT---KKP----------------VEEVAPSPIRPLLA 542
            :|         .:..|.....||..::.|   :||                |.||........:|
Yeast   339 IEYLKTRMKVLHVISETPKSFLQHLKQLTFIERKPLRFCSERLSLLVRTLEVTEVEDFTALKDIA 403

  Fly   543 FLETLTSNAEDGRILV------------DPVGGTLKYILLDPAEQFADIVAEARAIVIAGGTMQP 595
            ...||.|..|:|.:|:            :|:   :::..||.:.....:.....:::|..||:.|
Yeast   404 TFATLISTYEEGFLLIIEPYEIENAAVPNPI---MRFTCLDASIAIKPVFERFSSVIITSGTISP 465

  Fly   596 TKELKEQLFTGCHDRLVERFYNHVVANDAILPFVISNGPSGAPLSFKFAHRGSAEMLRELSMILR 660
            .......|   ....::::.|...:|..:.||.:|:.|.....:|.:|..|....::|....:|.
Yeast   466 LDMYPRML---NFKTVLQKSYAMTLAKKSFLPMIITKGSDQVAISSRFEIRNDPSIVRNYGSMLV 527

  Fly   661 NLCQVVPGGVVCFLPSYEYLDKVYKYLEQSGTLETISGRKSVFREVSGSAEQLLDNYALAIKRPA 725
            ...::.|.|:|.|.|||.|::.:....:..|.|:.:...|.:..|...:.|..|   ||...|.|
Yeast   528 EFAKITPDGMVVFFPSYLYMESIVSMWQTMGILDEVWKHKLILVETPDAQETSL---ALETYRKA 589

  Fly   726 ---SYGALLLSVVGGKLSEGLNFADDLGRAVLVVGLPYSNSLSPELRQRMQHLDEKLGPGAGNEY 787
               ..||:||||..||:|||::|....||.||::|:|:..:.|..|:.|::.:.|.... ..|::
Yeast   590 CSNGRGAILLSVARGKVSEGIDFDHQYGRTVLMIGIPFQYTESRILKARLEFMRENYRI-RENDF 653

  Fly   788 YENLCVKAVNQCIGRAVRHIKDYACVYLLDKRFADPKIRGKLPKWISRHIVEAN 841
            .....::...||:||.:|...||..:.|.|:||:  :.|.:|||||::.:.:|:
Yeast   654 LSFDAMRHAAQCLGRVLRGKDDYGVMVLADRRFS--RKRSQLPKWIAQGLSDAD 705

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11403	NP_569898.1	DEAD-like_helicase_N	42..>101	CDD:475120
		rad3	187..837	CDD:273169	167/715 (23%)
RAD3	NP_011098.3	rad3	7..717	CDD:273169	176/769 (23%)