DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11403 and AT1G79890

DIOPT Version :9

Sequence 1:	NP_569898.1	Gene:	CG11403 / 31072	FlyBaseID:	FBgn0026876	Length:	861	Species:	Drosophila melanogaster
Sequence 2:	NP_178107.1	Gene:	AT1G79890 / 844328	AraportID:	AT1G79890	Length:	882	Species:	Arabidopsis thaliana

Alignment Length:	960	Identity:	321/960 - (33%)
Similarity:	459/960 - (47%)	Gaps:	211/960 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 QEF-GFPYSPYEIQEQLMQELFQVLERGQVGIFESPTGTGKSLTLTCGALTWLARHEELVRTEML 79
            :|| .|||.||.||...|..|:|.|::|.|.:.||||||||||::.|.||.||...:|
plant     5 REFPAFPYKPYSIQIDFMNALYQFLDKGGVSMLESPTGTGKSLSIICSALQWLTDRKE------- 62

  Fly    80 ARIRGVEQELAKLK-EESEQSSNWL------ESQGK-----------------------SRAQRA 114
            .|..|:.:|..|:. .:.|...:|:      |:.|.                       :..::|
plant    63 KRNSGLTEESHKVDGNDDEDEPDWMRNFTLNEADGANGDKSIKNTKSPFSLRKHAKEVFTEGEKA 127

  Fly   115 ELLRLQHLQALLDKQEQQLDQIRKGAKKHKRQGRVHPGKLEELEKDLDPESDSDSEHETADGPQE 179
            :.|..|  :.|||:.|.| |:...|....||:    |.      :..|..|..|.|.|     .:
plant   128 DELNDQ--EFLLDEYESQ-DESSPGGGNSKRK----PA------RGFDSSSSEDEEDE-----ND 174

  Fly   180 AAEDRYRPVQIFFCSRTHSQLAQIVAELRKTPHGQSVRSISLGSRQQLCGNPAVRKLKHVGLMNE 244
            .::|.....::||||||||||:|.|.|||||...:.::.:.||||:.||.|..|.||.:|..:||
plant   175 CSDDEQGGFKVFFCSRTHSQLSQFVKELRKTVFAKKLKVVCLGSRKNLCINEDVLKLGNVTRINE 239

  Fly   245 RCLDMATKKARPNPSKKSRLTA-------EANSRCP----------FKAASLVESLRDLALTEPL 292
            ||||:..||. ...|||..|.|       :|:.|||          |||.|..:        |.:
plant   240 RCLDLQKKKI-SQVSKKKNLGANVRIVRTKASCRCPMLRKHKLQREFKAESFQQ--------EAM 295

  Fly   293 DIEELANEGTACGGCSYYASRSAVEHAQLILLPYQLLLQKSARNQLGISLKGSIVIVDEAHNLLD 357
            |||:|...|.....|.||.||.....|.|::||||.||.||:|..||:|||.|:||:||||||.|
plant   296 DIEDLVQLGREMRTCPYYGSRRMAPAADLVILPYQSLLSKSSRESLGLSLKNSVVIIDEAHNLAD 360

  Fly   358 SVAQLHGSEISRQQLERAKVQISGYKDHFQKRFTTKNLLKINQIIFIIRRLLKILDQRKELQS-- 420
            ::..:|.::::..|||.....|..|...||......|...|..::.:.|..||.|...:.|.|
plant   361 TLLSMHDAKLTVSQLEDIHCSIESYLGRFQNLLGAGNRRYIQIMLILTRAFLKPLASDRNLSSVN 425

  Fly   421 --------------NGCSMMRTYELTAEGDFFNIDLCELLDFCARTRFARKVQGRADRMEREPRP 471
                          ..|| |..|:.....:..||:|.:||.:...:....||.|..:|:
plant   426 VGLDTENPSKSKPCGACS-MAIYDFLFSLNIDNINLVKLLAYIKESNIIHKVSGYGERV------ 483

  Fly   472 SENQAPVSTARSLILQRLASEQKLKEKTKSVKRRVEDINKEDKAEELQEQQKPTKKPVEEVAPSP 536
                                                       |..||      |.||.....|.
plant   484 -------------------------------------------AAMLQ------KDPVAHEEMSK 499

  Fly   537 IRPLLAF---LETLTSNAEDGRILVDPV--------GGTLKYILLDPAEQFADIVAEARAIVIAG 590
            :....||   |..||:|..||||::...        ||.:||::|..|:.|:::|.||.|:::||
plant   500 LTSFRAFSDMLVALTNNNGDGRIIISRTSSSTSGQHGGYIKYVMLTGAKLFSEVVDEAHAVILAG 564

  Fly   591 GTMQPTKELKEQLFTGCHDRLVERF-YNHVVANDAILPFVISNGPSGAPLSFKFAHRGSAEMLRE 654
            ||:||.:|.:|:||.......::.| .:|:|..::|:|..:|:||||....|..:.|.|..|::|
plant   565 GTLQPIEETRERLFPWLPSNQLQFFSCSHIVPPESIMPIAVSHGPSGQSFDFSHSSRSSIGMIQE 629

  Fly   655 LSMILRNLCQVVPGGVVCFLPSYEYLDKVYKYLEQSGTLETISGRKSVFRE--VSGSAEQLLDNY 717
            |.:::.||..|||.|::.|..|:||..:|:.....||.|..|..:|.||||  .:...|.:|.:|
plant   630 LGLLMSNLVAVVPEGIIVFFSSFEYETQVHTAWSNSGILRRIVKKKRVFREPRKNTEVEAVLRDY 694

  Fly   718 ALAIKRPASYGALLLSVVGGKLSEGLNFADDLGRAVLVVGLPYSNSLSPELRQRMQHL------- 775
            ..||:  :..||::|:|||||:|||:||:|.:.|.|::|||||.:....||.:|::|:
plant   695 KEAIE--SERGAIMLAVVGGKVSEGINFSDSMCRCVVMVGLPYPSPSDIELLERIKHIEGRADSD 757

  Fly   776 ----------------DEKLGPGA-------GNEYYENLCVKAVNQCIGRAVRHIKDYACVYLLD 817
                            |.:.|.|.       |.|||||||:|||||.||||:||.||||.:.|:|
plant   758 SIKPSVTLVDDSYYSGDVQAGFGVLKSCKRRGKEYYENLCMKAVNQSIGRAIRHEKDYASILLVD 822

  Fly   818 KRFA-DPKIR-------GKLPKWISRHIVEANAANGGFGAVQGRTARFFK 859
            .|:: ||..|       .||||||...::.:..   |:|.|.....:|||
plant   823 ARYSNDPSKRTSHSHPSNKLPKWIKDRLIYSTK---GYGDVHRLLHQFFK 869

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11403	NP_569898.1	DinG	15..841	CDD:224120	315/940 (34%)
		DEXDc2	16..394	CDD:214693	152/425 (36%)
		Helicase_C_2	659..836	CDD:290046	88/216 (41%)
AT1G79890	NP_178107.1	DinG	1..846	CDD:224120	313/932 (34%)
		DEAD_2	187..375	CDD:284209	86/196 (44%)
		Helicase_C_2	636..849	CDD:290046	88/214 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	147	1.000	Domainoid score	I1457
eggNOG	1	0.900	-	-		E1_COG1199
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H68973
Inparanoid	1	1.050	421	1.000	Inparanoid score	I434
OMA	1	1.010	-	-		QHG57144
OrthoDB	1	1.010	-	-		D186062at2759
OrthoFinder	1	1.000	-	-		FOG0003100
OrthoInspector	1	1.000	-	-		oto4255
orthoMCL	1	0.900	-	-		OOG6_102316
Panther	1	1.100	-	-	LDO	PTHR11472
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2476
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840