Protein Alignment CG11403 and brip1

DIOPT Version :10

• Sequence 1: NP_569898.1
• Gene: CG11403 / 31072
• FlyBaseID: FBgn0026876
• Length: 861
• Species: Drosophila melanogaster
• Sequence 2: XP_073779429.1
• Gene: brip1 / 794038
• ZFINID: ZDB-GENE-081107-11
• Length: 1364
• Species: Danio rerio
• Alignment Length: 1013
• Identity: 258/1013 - (25%)
• Similarity: 390/1013 - (38%)
• Gaps: 264/1013 - (26%)

  Fly    12 TPGAQEFGFPYSPYEIQEQLMQELFQVLERGQVGIFESPTGTGKSLTLTCGALTW---------- 66
            |.|..:..||...|..|..:|..:.:.|..||..:.|||||:||||.|.|.||.|
Zfish     9 TIGGVKINFPCKAYPSQLAMMNSIIRGLNNGQHCLLESPTGSGKSLALLCSALAWQQAQFVKEQD 73

  Fly    67 ------------------LARHEELVRTEMLARIRGVEQELAKLKEESEQSSNWLESQGKSRAQR 113
                              .|.|....::....|...........:..|.|.:..|...|||...:
Zfish    74 AGTGFADCKKSEVVTPCQCACHSRNAQSTFNTRASRPPTVHLTCEGTSAQPTTPLSKGGKSDQHK 138

  Fly   114 AELL--RL-QHLQALLDKQEQQLDQIRKGAKKHKRQGRVHP-GKLEELEKDLDPESDSDSEHETA 174
            ...|  || :.|||.|:..|.. |..:...|:.:..|.... .|...|||.:....|.|.|.|:.
Zfish   139 KPSLSSRLSEKLQASLNNGEHD-DDFKNDRKRIRTPGTEQKISKRRCLEKGVIYIDDDDEEEESL 202

  Fly   175 DGP-------------------------------------------QEAAE------------DR 184
            :.|                                           |:.||            .:
Zfish   203 ERPVPGAQTWTMELNNGARADSCQSQPQCCSPVSCSLCPCANLKAGQKMAEMSKDNEKDKDGSGK 267

  Fly   185 YRPVQIFFCSRTHSQLAQIVAELRKTPHGQSVRSISLGSRQQLCGNPAVRKLKHVGLMNERCLDM 249
            .:..:|||.:|||.|:.||..||::|.: .:|....|.||...|.:|.|  :.|.. .||||
Zfish   268 KKIPKIFFGTRTHKQITQIARELKRTLY-STVPMTILSSRDHTCVHPEV--VPHAN-RNERC--- 325

  Fly   250 ATKKARPNPSKKSRLTAEANSRCPFKAASLVESLRDLA-------LTEPLDIEELANEGTACGGC 307
                       |..|.|:....|.:  ...|..:||.:       |.:..|||||...|.....|
Zfish   326 -----------KEFLEAKNGRSCRY--YHNVHKMRDQSTLQWVHGLHQAWDIEELVRLGGKLRSC 377

  Fly   308 SYYASRSAVEHAQLILLPYQLLLQKSARNQLGISLKGSIVIVDEAHNLLDSVAQLHGSEISRQQL 372
            :|||:|..::.|.::..||..||....|..:.|:||..||::|||||:.|...:.....:::.||
Zfish   378 AYYAARELMQEACIVFCPYNYLLDPLIRESMEINLKEQIVVLDEAHNIEDCARESASFTLNQAQL 442

  Fly   373 ERAKVQISGYKDHFQKRFTTKNLLKINQIIFIIRRLLKILDQRKELQSNGCSMMRTYELTAEGDF 437
            ..|:.:|.|...|                  .|||     ||.:.|.:..||:....:.:..|
Zfish   443 LLARDEIDGMVTH------------------NIRR-----DQHRPLLAFCCSLTNWVQESCGG-- 482

  Fly   438 FNIDLCELLDFCARTRFARKVQGRADRMEREPRPSENQAPVSTA-------RSL--------ILQ 487
                                         .|.|..|:...|.|.       |.|        :||
Zfish   483 -----------------------------LEEREYESSCKVWTGVEVLGIFRGLGITADTFPLLQ 518

  Fly   488 R-LASEQKLKEKTKSVKRRVEDINKEDKAEELQEQQKPTKKPVEEVAPSPIRPLLAFLETLTSN- 550
            : ||:..:.:|:...|..|.|.:            |.||   :.....|.::.|...||.|...
Zfish   519 KNLAAVLEKEERVGLVNGREETV------------QVPT---ISSNTQSMLKSLFMVLEFLFRQN 568

  Fly   551 ---AEDGRI-------------LVDPVG------------------GTLKYILLDPAEQFADIVA 581
               |:|.|:             |.|..|                  .||.:..|:||..|:|:.:
Zfish   569 CRFADDYRVALQQSYMWTTQQDLPDAQGFFARPHRRRQSNRTKTLVHTLSFWCLNPAVAFSDLSS 633

  Fly   582 EARAIVIAGGTMQPTKELKEQL---FTGCHDRLVERFYNHVVANDAILPFVISNGPSGAPLSFKF 643
            ..|:||:..||:.|......:|   |:      ::...|||:....:....|..||.|..|...|
Zfish   634 TVRSIVLTSGTLSPMGSFSSELGIKFS------IQLEANHVINKSQVWVGTIGAGPQGRKLCATF 692

  Fly   644 AHRGSAEMLRELSMILRNLCQVVPGGVVCFLPSYEYLDKVYKYLEQSGTLETISGRKSVFREVSG 708
            .|..:.....|:..:|..:|..|..||:||||||:.|||:......:|..:.:...|:|..|..|
Zfish   693 QHAETFAFQDEVGALLLKVCHTVSRGVLCFLPSYKMLDKLRDRWTNTGLWDKLEECKTVITEPRG 757

  Fly   709 SA----EQLLDNYALAIKRPASY-----GALLLSVVGGKLSEGLNFADDLGRAVLVVGLPYSNSL 764
            ..    ::||..|..||:..|:.     ||||::|..||:||||:|.||..|||:.:|:|:.|..
Zfish   758 GGKGDFDELLQTYYEAIRGTAAKGEKRDGALLVAVCRGKVSEGLDFTDDNARAVVTIGIPFPNIK 822

  Fly   765 SPELRQRMQHLD---EKLGPGAGNEYYENLCVKAVNQCIGRAVRHIKDYACVYLLDKRF-ADPK- 824
            ..::..:|::.|   :..|...|..:||....:|:||.:||.:||..|:..:.|:|.|| .:|.
Zfish   823 DLQVELKMKYNDKHAKSRGLLPGGRWYEIQAYRALNQALGRCIRHRNDWGALILVDDRFRTNPNK 887

  Fly   825 -IRGKLPKWISRHIVEANAANGGFGAVQGRTARFFKGR 861
             |.| |.||:.:.:...:...|...:::.    |.:|:
Zfish   888 YITG-LSKWVRQLVRHHDTFTGAMQSLKS----FSQGQ 920

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11403	NP_569898.1	DEAD-like_helicase_N	42..>101	CDD:475120	21/86 (24%)
		rad3	187..837	CDD:273169	199/725 (27%)
brip1	XP_073779429.1	None