Protein Alignment CG11403 and ddx11

DIOPT Version :10

• Sequence 1: NP_569898.1
• Gene: CG11403 / 31072
• FlyBaseID: FBgn0026876
• Length: 861
• Species: Drosophila melanogaster
• Sequence 2: NP_001164296.1
• Gene: ddx11 / 493192
• XenbaseID: XB-GENE-969935
• Length: 895
• Species: Xenopus tropicalis
• Alignment Length: 914
• Identity: 337/914 - (36%)
• Similarity: 515/914 - (56%)
• Gaps: 103/914 - (11%)

  Fly    13 PGAQEFGFPYSPYEIQEQLMQELFQVLERGQVGIFESPTGTGKSLTLTCGALTWLARHEELVRTE 77
            |.|..|.|||.||.||||.|::|:|.||.|:||||||||||||||:|.|||||||...|...|.|
 Frog     8 PAALTFPFPYEPYPIQEQFMEKLYQALEAGKVGIFESPTGTGKSLSLICGALTWLQDFETKKRQE 72

  Fly    78 MLARIRGVEQELAKLKEESEQSS--NWL--------ESQGKSRAQRAELLRLQHLQALLDKQEQQ 132
            ....:...:.|| |.|:.|..|:  :|:        |...|::.:..:|.|        .|:|:.
 Frog    73 EAQALSVADTEL-KEKDTSASSTEPDWIAQFVQMKEEMDIKNKIKEEQLRR--------KKREEH 128

  Fly   133 LDQIR-----KGAKKHKRQGRVHPGKLEELEK------------DLDPES------DSDSEHETA 174
            |.|::     |.|.|.||:......:|.:|.:            :||.|.      :.:|:.||.
 Frog   129 LKQMKHNVQLKFASKRKREEDDETMRLLQLSQQILSGGGEKEAIELDKEEQELLLVEYESDEETK 193

  Fly   175 DGP-----QEAAEDRYRPVQIFFCSRTHSQLAQIVAELRKTPHGQSVRSISLGSRQQLCGNPAVR 234
            .||     :|..|:.: ..:|::||||||||:|.|.|::|:|.|:..|.:||||||.:|.|..||
 Frog   194 KGPDRLEDEEDLEEEH-VTKIYYCSRTHSQLSQFVHEVQKSPFGKQTRLVSLGSRQNMCVNDDVR 257

  Fly   235 KLKHVGLMNERCLDMAT---KKARPNPSKKSRLTAEANSRCPFKAASLVESLRDLALTEPLDIEE 296
            :|.:|.|:|:||::|..   :|....|.:|.|  .|:.:.|||.:...::.|||..|.|..|||:
 Frog   258 RLGNVQLINDRCMEMQRNKHEKKNKEPERKKR--QESRAACPFYSYEQMQFLRDETLVEVKDIEQ 320

  Fly   297 LANEGTACGGCSYYASRSAVEHAQLILLPYQLLLQKSARNQLGISLKGSIVIVDEAHNLLDSVAQ 361
            |.:.......|.||:||.|:..||:::||||:||.:|:|...||.||..:||:||||||:|::..
 Frog   321 LVSLAREVKACPYYSSRYAIPTAQVVVLPYQMLLHESSRKASGIKLKDQVVIIDEAHNLIDTITC 385

  Fly   362 LHGSEISRQQLERAKVQISGYKDHFQKRFTTKNLLKINQIIFIIRRLLKILDQR-------KELQ 419
            ::.|::|..||.:|..|:..|.|.::.|...|||:.:.|::|::.:.::::...       :::.
 Frog   386 MYSSQVSGAQLCQAHSQLMQYMDRYRSRLKAKNLMYVKQLVFLLEKFVQVMGGNVKQNPSFQKVA 450

  Fly   420 SNGCSMMRTYELTAEGDFFNIDLCELLDFCARTRFARKVQGRADRMEREPRPSENQAPVSTARSL 484
            .:|.::....:........||:|.::..:|.::..:||:.|..::.:.......|:.........
 Frog   451 QDGTTLKSINDFLFHSQIDNINLFKIQRYCTKSMISRKLSGFVEKFKGTETCLANKESQKAGLQQ 515

  Fly   485 ILQRLASEQKLKEKTKSVKRRVEDINKEDKAEELQEQQKPTKKPVEEVAPSPIRPLLAFLETLTS 549
            .||.|:  ||.:....:.:..:||      ||..|.:           ..||:..:..||..||:
 Frog   516 FLQDLS--QKSRHTVGAPEGALED------AENGQLR-----------TASPLMQIEGFLSALTN 561

  Fly   550 NAEDGRILVDPVG----GTLKYILLDPAEQFADIVAEARAIVIAGGTMQPTKELKEQLFTGC--- 607
            ..:|||:::...|    .:||:::|:||..||:::.|.|:::||||||||..:.|:||....
 Frog   562 ANQDGRVILHMQGTVAQSSLKFLMLNPAVHFAEVLKECRSVIIAGGTMQPVSDFKQQLLISAGLS 626

  Fly   608 HDRLVERFYNHVVANDAILPFVISNGPSGAPLSFKFAHRGSAEMLRELSMILRNLCQVVPGGVVC 672
            .:|:.|....||:..:.|||.|:.:||:...|.|.:..|...||:.|...||.|||..||||:||
 Frog   627 PERITEFSCGHVIPAENILPIVLCSGPTNQQLEFTYQKRDLPEMMDETGRILTNLCNFVPGGLVC 691

  Fly   673 FLPSYEYLDKVYKYLEQSGTLETISGRKSVFREV--SGSAEQLLDNYALAIKR-----PASYGAL 730
            |.|||||..::.::.|:||.|:.::.:|.:|:|.  :...:|:|..|:..||.     .|..|||
 Frog   692 FFPSYEYQKRIQEHWEKSGLLKRLALKKKIFQEPKRANQVDQVLVEYSKCIKNCSQSGGAQNGAL 756

  Fly   731 LLSVVGGKLSEGLNFADDLGRAVLVVGLPYSNSLSPELRQRMQHLDEKL----GPGAGNEYYENL 791
            |.||||||:|||:||:|||||.:::||:||.|..||||:::|.:||:.|    |..||....|||
 Frog   757 LFSVVGGKMSEGINFSDDLGRCIVMVGMPYPNIRSPELQEKMSYLDKTLPKTEGVSAGRVLIENL 821

  Fly   792 CVKAVNQCIGRAVRHIKDYACVYLLDKRFADPKIRGKLPKWI-SRHIVEANAANGGFGAVQGRTA 855
            |:|||||.||||:||..|||.:.|||.|::.|.|.||||:|| |...|:.|     |||......
 Frog   822 CMKAVNQSIGRAIRHRGDYASIVLLDHRYSRPAILGKLPQWIRSSTQVKPN-----FGAAFATIR 881

  Fly   856 RFFK 859
            :||:
 Frog   882 KFFQ 885

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11403	NP_569898.1	DEAD-like_helicase_N	42..>101	CDD:475120	32/60 (53%)
		rad3	187..837	CDD:273169	255/678 (38%)
ddx11	NP_001164296.1	DEXDc	15..>136	CDD:214692	55/129 (43%)
		rad3	210..876	CDD:273169	259/691 (37%)