Protein Alignment CG11403 and ercc2

DIOPT Version :9

• Sequence 1: NP_569898.1
• Gene: CG11403 / 31072
• FlyBaseID: FBgn0026876
• Length: 861
• Species: Drosophila melanogaster
• Sequence 2: NP_957220.2
• Gene: ercc2 / 393900
• ZFINID: ZDB-GENE-040426-997
• Length: 760
• Species: Danio rerio
• Alignment Length: 885
• Identity: 190/885 - (21%)
• Similarity: 339/885 - (38%)
• Gaps: 254/885 - (28%)

  Fly    20 FPYS-PYEIQEQLMQELFQVLERGQVGIFESPTGTGKSLTLTCGALTWLARHEELVRTEMLARIR 83
            |||. .|..|...|.||.:.|:....|:.|.|:||||:::|    |:.:..:::....|:
Zfish    12 FPYDYIYPEQYSYMLELKRTLDAKGHGVLEMPSGTGKTISL----LSLIVAYQKTYPLEV----- 67

  Fly    84 GVEQELAKLKEESEQSSNWLESQGKSRAQRAELLRLQHLQALLDKQEQQLDQIRKGAKKHKRQGR 148
                                                                             
Zfish    68 ----------------------------------------------------------------- 67

  Fly   149 VHPGKLEELEKDLDPESDSDSEHETADGPQEAAEDRYRPVQIFFCSRTHSQLAQIVAELRK---- 209
                                                   .::.:||||..::.::|.||||
Zfish    68 ---------------------------------------TKLVYCSRTVPEIEKVVEELRKLMDY 93

  Fly   210 ----TPHGQSVRSISLGSRQQLCGNPAVRKLKHVGLMNERCLDMATKKAR----PNPSKKSRLTA 266
                |.......:::|.||:.||.:|.|..|:....::.:|..:.....|    .||::..
Zfish    94 YSKQTGVKNDFLALALSSRKNLCIHPEVSSLRFGKEVDGKCHSLTASYIRAQHQSNPNQPV---- 154

  Fly   267 EANSRCPFKAASLVESLRDLALTEPL-----DIEELANEGTACGGCSYYASRSAVEHAQLILLPY 326
                 |.|     .|...::....|:     ::::|.:.|...|.|.|:.:|.|:.||.:::..|
Zfish   155 -----CQF-----YEEFDNVGRQVPIPPGIYNLDDLKDFGRRKGWCPYFLARYALLHANIVVYSY 209

  Fly   327 QLLLQKSARNQLGISL-KGSIVIVDEAHNL----LDSVAQLHGSEISRQQLERAKVQISGYKDHF 386
            ..||.....:.:...| |.|:|:.|||||:    :||::    ..|:|:.|:|.:..:...::..
Zfish   210 HYLLDPKIADLVSKELAKKSVVVFDEAHNIDNVCIDSMS----VNITRRTLDRCQTNVETLQNTI 270

  Fly   387 QKRFTTKNLLKINQIIFIIRRL---LKILDQRKE--------------LQSNGCSMMRTYELTAE 434
             .|....:..|:.:   ..|||   ||..:..:|              ||......:||.|
Zfish   271 -SRIKETDAAKLRE---EYRRLVEGLKEANVARETDIYLSNPVLPDEILQEAVPGSIRTAE---- 327

  Fly   435 GDFFNIDLCELLDFC-ARTRFARKVQGRADRMEREPRPSENQAPVSTARSLILQRLASEQK---- 494
              .|...:...|::. ||.|....||..|.:..::                |.:::..::|
Zfish   328 --HFVGFMKRFLEYLKARLRIHHVVQESAPQFLKD----------------IFEKVCIDRKPLRF 374

  Fly   495 LKEKTKSVKRRVEDINKEDKAEELQEQQKPTKKPVEEVAP-SPIRPLLAFLETLTSNAEDG-RIL 557
            ..|:.:|:.|.:|                     :.::|. ||| .|::...||.|....| .|:
Zfish   375 CAERLRSLLRTLE---------------------IADIADFSPI-TLISHFATLVSTYSKGFTII 417

  Fly   558 VDP--------VGGTLKYILLDPAEQFADIVAEARAIVIAGGTMQPTKELKEQLFTGCHDRLVE- 613
            ::|        ....|.:..:||:.....:....:.::|..||:.|         ...:.|:::
Zfish   418 IEPFEDKTPTIANPVLHFSCMDPSIAIKPVFGRFQTVIITSGTLSP---------LDIYPRILDF 473

  Fly   614 -----RFYNHVVANDAILPFVISNGPSGAPLSFKFAHRGSAEMLRELSMILRNLCQVVPGGVVCF 673
                 ..:...:|...:.|.::..|.....::.||..|....::|....:|..:..:||.|:|.|
Zfish   474 RPVTMASFTMTLARTCLCPLIVGRGNDQVAMTSKFETREDFAVIRNYGNLLLEMSAIVPDGIVAF 538

  Fly   674 LPSYEYLDKVYKYLEQSGTLETISGRKSVFREVSGSAE--QLLDNYALAIKRPASYGALLLSVVG 736
            ..||.|::.:.....:.|.||.|...|.:|.|...:||  ..|:.|..|.:.  ..||:||||..
Zfish   539 FTSYMYMENIVASWYEQGILENIQRNKLIFIETQDAAETSMALEKYQEACEN--GRGAILLSVAR 601

  Fly   737 GKLSEGLNFADDLGRAVLVVGLPYSNSLSPELRQRMQHLDEKLGPGAGNEYYENLCVKAVNQCIG 801
            ||:|||::|....||||::.|:||..:.|..|:.|:::|.::. ....|::.....::...||:|
Zfish   602 GKVSEGIDFVHHFGRAVIMFGVPYVYTQSRILKARLEYLRDQF-QIRENDFLTFDAMRHAAQCVG 665

  Fly   802 RAVRHIKDYACVYLLDKRFADPKIRGKLPKWISRHIVEAN 841
            ||:|...||..:...|||:|....|||||:||..|:.:.:
Zfish   666 RAIRGKTDYGLMIFADKRYARADKRGKLPRWIQEHLTDGS 705

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11403	NP_569898.1	DinG	15..841	CDD:224120	190/883 (22%)
		DEXDc2	16..394	CDD:214693	73/396 (18%)
		Helicase_C_2	659..836	CDD:290046	64/178 (36%)
ercc2	NP_957220.2	rad3	7..708	CDD:273169	190/885 (21%)
		DEXDc2	8..278	CDD:214693	73/397 (18%)
		HBB	270..413	CDD:284245	35/190 (18%)
		HELICc2	542..686	CDD:214694	49/146 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1199
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D141017at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820