Protein Alignment CG11403 and DDX11

DIOPT Version :9

• Sequence 1: NP_569898.1
• Gene: CG11403 / 31072
• FlyBaseID: FBgn0026876
• Length: 861
• Species: Drosophila melanogaster
• Sequence 2: XP_016874407.1
• Gene: DDX11 / 1663
• HGNCID: 2736
• Length: 1091
• Species: Homo sapiens
• Alignment Length: 912
• Identity: 323/912 - (35%)
• Similarity: 462/912 - (50%)
• Gaps: 166/912 - (18%)

  Fly    14 GAQEFGFPYSPYEIQEQLMQELFQVLERGQVGIFESPTGTGKSLTLTCGALTWLARHEELVRTEM 78
            ||..|.||::||.|||..|.||::|||.|::|||||||||||||:|.||||:||...|:..|.|
Human    45 GAIHFPFPFTPYSIQEDFMAELYRVLEAGKIGIFESPTGTGKSLSLICGALSWLRDFEQKKREE- 108

  Fly    79 LARIRGVEQELAKLKEESEQS-------------------SNWLESQGKSRAQRAELLRLQHLQA 124
              ..|.:|.....|.:|.::|                   ..|:....:.:.:|..:.||:..||
Human   109 --EARLLETGTGPLHDEKDESLCLSSSCEGAAGTPRPAGEPAWVTQFVQKKEERDLVDRLKAEQA 171

  Fly   125 LLDKQEQQLDQIR-----KGAKKHKRQGR-------------VHPG----KLEELEKDLD----P 163
            ...::|::|.|::     |.|.|..||..             :..|    :||:||...:    .
Human   172 RRKQREERLQQLQHRVQLKYAAKRLRQEEEERENLLRLSREMLETGPEAERLEQLESGEEELVLA 236

  Fly   164 ESDSDSEHETADGPQEAAED--RYRPVQIFFCSRTHSQLAQIVAELRKTPHGQSVRSISLGSRQQ 226
            |.:||.|.:.|....|..:|  .....:|::||||||||||.|.|::|:|.|:.||.:||||||.
Human   237 EYESDEEKKVASRVDEDEDDLEEEHITKIYYCSRTHSQLAQFVHEVKKSPFGKDVRLVSLGSRQN 301

  Fly   227 LCGNPAVRKLKHVGLMNERCLDMA----TKKARPNPSKKSRLTAEANSRCPFKAASLVESLRDLA 287
            ||.|..|:.|..|.|:|:||:||.    .||......|..|...|..:.|||.....:..|||.|
Human   302 LCVNEDVKSLGSVQLINDRCVDMQRSRHEKKKGAEEEKPKRRRQEKQAACPFYNHEQMGLLRDEA 366

  Fly   288 LTEPLDIEELANEGTACGGCSYYASRSAVEHAQLILLPYQLLLQKSARNQLGISLKGSIVIVDEA 352
            |.|..|:|:|...|.....|.||.||.|:..|||::||||:||..:.|...||.|:..:||:|||
Human   367 LAEVKDMEQLLALGKEARACPYYGSRLAIPAAQLVVLPYQMLLHAATRQAAGIRLQDQVVIIDEA 431

  Fly   353 HNLLDSVAQLHGSEISRQQLERAKVQISGYKDHFQKRFTTKNLLKINQIIFIIRRLLKILDQRKE 417
            |||:|::..:|..|:|..||.:|..|:..|.:.:.||...|||:.:.||::::.:.:.:|....:
Human   432 HNLIDTITGMHSVEVSGSQLCQAHSQLLQYVERYGKRLKAKNLMYLKQILYLLEKFVAVLGGNIK 496

  Fly   418 LQSNGCSMMRT-YELTAEGDFF------NIDLCELLDFCARTRFARKVQGRADRMEREPRPSENQ 475
            ...|..|:.:| .||....||.      ||:|.::..:|.::..:||:.|..:|          .
Human   497 QNPNTQSLSQTGTELKTINDFLFQSQIDNINLFKVQRYCEKSMISRKLFGFTER----------Y 551

  Fly   476 APVSTARSLILQRLASEQKLKEKTKSVKRRVEDINKEDKAEELQEQQKPTKKPVEEVAPSPIRPL 540
            ..|.::|.  ..:||..|:.   .:|::.|    ..|..|....|.|..|.:|.     ||:..:
Human   552 GAVFSSRE--QPKLAGFQQF---LQSLQPR----TTEALAAPADESQASTLRPA-----SPLMHI 602

  Fly   541 LAFLETLTSNAEDGRILVDPVG----GTLKYILLDPAEQFADIVAEARAIVIAGGTMQPTKELKE 601
            ..||..||:..:|||:::...|    .|||::||:||..||.:|.|.||:|||||||||.....|
Human   603 QGFLAALTTANQDGRVILSRQGSLSQSTLKFLLLNPAVHFAQVVKECRAVVIAGGTMQPAAGAVE 667

  Fly   602 -----------------QLFTGC------HDRLVER----------------------------- 614
                             :||.|.      ||...:|
Human   668 TPLLLHSVAPGSHVSQRKLFCGFKLKEKNHDSTFKRCLTSGSSCWPVPGWKLSAWWSFPVCLAAH 732

  Fly   615 -----------FYNHVVANDAILPFVISNGPSGAPLSFKFAHRGSAEMLRELSMILRNLCQVVPG 668
                       ...||:..|.|||.||.:|.|..||.|.|..|...:|:.|:..||.|||.||||
Human   733 LHLQFSAPPWLLPGHVIPPDNILPLVICSGISNQPLEFTFQKRELPQMMDEVGRILCNLCGVVPG 797

  Fly   669 GVVCFLPSYEYLDKVYKYLEQSGTLETISGRKSVFREVSGS--AEQLLDNYALAI-----KRPAS 726
            |||||.||||||.:|:.:.|:.|.|..::.||.:|:|...:  .||:|..|:..|     :|...
Human   798 GVVCFFPSYEYLRQVHAHWEKGGLLGRLAARKKIFQEPKSAHQVEQVLLAYSRCIQACGQERGQV 862

  Fly   727 YGALLLSVVGGKLSEGLNFADDLGRAVLVVGLPYSNSLSPELRQRMQHLDEKLGP-------GAG 784
            .|||||||||||:|||:||:|:|||.|::||:|:.|..|.||:::|.:||:.|.|       |:|
Human   863 TGALLLSVVGGKMSEGINFSDNLGRCVVMVGMPFPNIRSAELQEKMAYLDQTLSPRPGTPREGSG 927

  Fly   785 NE 786
            .|
Human   928 GE 929

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11403	NP_569898.1	DinG	15..841	CDD:224120	322/911 (35%)
		DEXDc2	16..394	CDD:214693	161/428 (38%)
		Helicase_C_2	659..836	CDD:290046	69/142 (49%)
DDX11	XP_016874407.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157754
Domainoid	1	1.000	176	1.000	Domainoid score	I3619
eggNOG	1	0.900	-	-		E1_COG1199
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H68973
Inparanoid	1	1.050	520	1.000	Inparanoid score	I1274
Isobase	1	0.950	-	0	Normalized mean entropy	S1862
OMA	1	1.010	-	-		QHG57144
OrthoDB	1	1.010	-	-		D141017at33208
OrthoFinder	1	1.000	-	-		FOG0003100
OrthoInspector	1	1.000	-	-		otm40277
orthoMCL	1	0.900	-	-		OOG6_102316
Panther	1	1.100	-	-	LDO	PTHR11472
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2476
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	15	14.760