Protein Alignment CG11403 and Xpd

DIOPT Version :10

• Sequence 1: NP_569898.1
• Gene: CG11403 / 31072
• FlyBaseID: FBgn0026876
• Length: 861
• Species: Drosophila melanogaster
• Sequence 2: XP_311900.4
• Gene: Xpd / 1272969
• VectorBaseID: AGAMI1_004304
• Length: 760
• Species: Anopheles gambiae
• Alignment Length: 706
• Identity: 169/706 - (23%)
• Similarity: 295/706 - (41%)
• Gaps: 117/706 - (16%)

  Fly   189 QIFFCSRTHSQLAQIVAEL--------RKTPHGQSVRSISLGSRQQLCGNPAVRKLKHVGLMNER 245
            ::.:||||..::.:::|||        ::|....::..:.|.||:.:|.:|.|.:.:...:::.|
Mosquito    69 KLIYCSRTVPEIEKVIAELKHLMNYYEKQTGAMPNITGLVLSSRKNMCIHPEVSREREGKIVDAR 133

  Fly   246 CLDMATKKARPNPSKKSRLTAEANSRCPFKAASLVESLRDLALTEPLDIEELANEGTACGGCSYY 310
            |..|.....|...:..     |:...|.:......|...::.......|::|...|.....|.|:
Mosquito   134 CYGMTASYVRERAAHD-----ESAPVCQYYEGFQAEGKENMLPPGVYSIDDLKEFGRERNWCPYF 193

  Fly   311 ASRSAVEHAQLILLPYQLLLQKSARNQLGISL-KGSIVIVDEAHNLLDSVAQLHGSEISRQQLER 374
            .||.|:..|.:::..|..||.......:...| :.|:|:.|||||:.:........:|:|:.:||
Mosquito   194 LSRFAINQAHVVVYSYYYLLDPKVAEVVSKELARESVVVCDEAHNIDNVCVDSMSVKINRRLIER 258

  Fly   375 AKVQISGYKDHFQKRFTTKNLLKINQIIFIIRRLLKILDQRKELQSNGCSMMRTYELTAEGDFFN 439
            :...|...:         |.:.::.:            |.::.|..
Mosquito   259 STTGIHNLE---------KKVAELKE------------DDKRRLNE------------------- 283

  Fly   440 IDLCELLDFCARTRFARKVQGRAD---RMEREPRPSENQAPVSTARSLILQRLASE-------QK 494
                         .:.|.|||..|   ..|.:...:....|....|.::...:.:.       ::
Mosquito   284 -------------EYVRLVQGLKDASFARETDMVLANPVLPNEVIREVVPGNIRNADHFLSFLKR 335

  Fly   495 LKEKTKSVKRRVEDINKEDKAEELQEQQKPT---KKPVEEVAPSPIRPLLAFLE----------- 545
            ..|..|| :.||:.:.:|..|..|::.|:..   :||:...| ..::.||..||
Mosquito   336 FIEYIKS-RLRVQHVVQESPAGFLRDVQQKVCIERKPLRFCA-DRLQSLLRTLEITDLSEYGPLS 398

  Fly   546 ------TLTSNAEDG-RILVDPV--------GGTLKYILLDPAEQFADIVAEARAIVIAGGTMQP 595
                  ||.|....| .|:::|.        ...:.:..||.:.....|....:::||..||:.|
Mosquito   399 VITSFATLVSTYTKGFTIIIEPFDDKTPTVSNPIMHFSCLDSSIAMKPIFQRFQSVVITSGTLSP 463

  Fly   596 TKELKEQLFTGCHDRLVERFYNHVVANDAILPFVISNGPSGAPLSFKFAHRGSAEMLRELSMILR 660
            .....:.|   ..:.:|...:...:|...:||.:::.|.....:|.:|..|....:.|....:|.
Mosquito   464 MDMYPKIL---DFEPVVMSSFTMTLARPCLLPMIVARGNDQVAISSRFETREDTAVTRNYGQLLV 525

  Fly   661 NLCQVVPGGVVCFLPSYEYLDKVYKYLEQSGTLETISGRKSVFREVSGSAE--QLLDNYALAIKR 723
            ...:.||.|||||..||.||:.|.......|.::|:...|.:|.|...:||  ..|.||..|.:
Mosquito   526 ETAKTVPDGVVCFFTSYLYLESVVASWYDQGIIDTLLRYKLLFIETQDNAETSYALMNYVKACE- 589

  Fly   724 PASYGALLLSVVGGKLSEGLNFADDLGRAVLVVGLPYSNSLSPELRQRMQHLDEKLGPGAGNEYY 788
             ...||:||:|..||:|||::|...||||||:.|:||..:.|..|:.|:.:|.::. ....|::.
Mosquito   590 -CGRGAVLLAVARGKVSEGVDFDHHLGRAVLMFGIPYVYTQSRILKARLDYLRDQF-QIRENDFL 652

  Fly   789 ENLCVKAVNQCIGRAVRHIKDYACVYLLDKRFADPKIRGKLPKWISRHIVEANAAN 844
            ....::...||:|||:|...||..:...||||:....||||||||..|:.: |.:|
Mosquito   653 TFDALRHAAQCVGRAIRGKTDYGIMIFADKRFSRQDKRGKLPKWIQEHLTD-NLSN 707

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11403	NP_569898.1	DEAD-like_helicase_N	42..>101	CDD:475120
		rad3	187..837	CDD:273169	166/697 (24%)
Xpd	XP_311900.4	rad3	7..708	CDD:273169	169/706 (24%)