Protein Alignment CG11403 and rtel1

DIOPT Version :10

• Sequence 1: NP_569898.1
• Gene: CG11403 / 31072
• FlyBaseID: FBgn0026876
• Length: 861
• Species: Drosophila melanogaster
• Sequence 2: XP_031750114.1
• Gene: rtel1 / 100487920
• XenbaseID: XB-GENE-6035930
• Length: 1269
• Species: Xenopus tropicalis
• Alignment Length: 915
• Identity: 229/915 - (25%)
• Similarity: 363/915 - (39%)
• Gaps: 254/915 - (27%)

  Fly    20 FPYSPYEIQEQLMQELFQVLERGQVGIFESPTGTGKSLTLTCGALTWLARHEELVRTEMLA-RIR 83
            ||:.||:.||..|.::.|.|::|..|:.||||||||:|.|.|..|.|...:::.:....:| |:.
 Frog    13 FPFQPYKCQEDYMGKVIQCLQQGVNGVLESPTGTGKTLCLLCATLAWRQHYKDGISARKIAERMN 77

  Fly    84 GVEQELAKLKEESEQSSNWLESQGKSRAQRAELLRLQHLQALLDKQEQQLDQIRKGAKKHKRQGR 148
            |.|    ...|....:.....::|::.|..:::
 Frog    78 GAE----LFPERPAAAWGGASAEGQASAYYSDV-------------------------------- 106

  Fly   149 VHPGKLEELEKDLDPESDSDSEHETADGPQEAAEDRYRPVQIFFCSRTHSQLAQIVAELRKTPHG 213
                                                   .:|.:.|||||||.|:::||:.|.:.
 Frog   107 ---------------------------------------PKIIYASRTHSQLTQVISELKHTVYR 132

  Fly   214 QSVRSISLGSRQQLCGNPAVRKLKHVGLMNERCLDMATKKARPNPSKKSRLTAEANSR-CPFKAA 277
            ..|  ..||||:|||.:|.|                  ||...|.:|.....::.::| |.| ..
 Frog   133 PKV--CVLGSREQLCIHPEV------------------KKQESNHAKVHMCRSKVSTRTCHF-YN 176

  Fly   278 SLVESLRDLALTEP-LDIEELANEGTACGGCSYYASRSAVEHAQLILLPYQLLLQKSARNQLGIS 341
            ::.|...:..||.. ||||:|...||....|.||.||:..:.|.:|.:||..||...:|....|.
 Frog   177 NVEEKSTEKDLTNHILDIEDLVKSGTKHRACPYYLSRNLKQQADIIFMPYNYLLDPKSRRAHNID 241

  Fly   342 LKGSIVIVDEAHNLLDSVAQLHGSEISRQQLERAKVQISGYKDHFQKRFTTKNLLK-INQIIFII 405
            |||::||.|||||                 :||.....|.:.      .|..:|.. |:.:..::
 Frog   242 LKGTVVIFDEAHN-----------------VERMCEDSSSFD------LTPYDLASGIDAMDLVL 283

  Fly   406 RRLLKILDQRK-------ELQSNGCSMMRTYELTAEGDFFNIDLCELLDFCARTRFARKVQGRAD 463
            :..::.::|::       :.||:|.::                  ||.|..       ||  :|.
 Frog   284 KEQMENVEQKRYQAEFNMDSQSSGLTL------------------ELEDLA-------KV--KAA 321

  Fly   464 RMEREPRPSENQAP-----VSTARSLILQRLA-------SEQKLKEKTKSVKRRV---------- 506
            .|:.|......|.|     |:...|.|.|..|       ::.||.|..:.:.:.|
 Frog   322 LMQLENSIESTQLPPGGGGVTKVGSYIFQLFAASGITFDTKAKLLESLEQIIQHVGGSSGIFTNT 386

  Fly   507 ----------------------------EDINKEDKAEELQEQQKPTKKPVEEVAPSPIRPLLAF 543
                                        ::|:|..|. .:.......|||..:|..:
 Frog   387 MGLQKLADIIQIVFSMEPPEGANVSSFNQNISKYYKV-HIHPDTNQRKKPRGDVWSN-------- 442

  Fly   544 LETLTSNAEDGRILVDPVGGTLKYILLDPAEQFADIVAE-ARAIVIAGGTMQP----TKELKEQL 603
                 |..:.|::        |.|....|.....|:|.: .|.:::..||:.|    |.|::...
 Frog   443 -----SKKQGGKV--------LSYWCFSPGYTMHDLVRQGVRCVILTSGTLCPLSSFTMEMQIPF 494

  Fly   604 FTGCHDRLVERFYNHVVANDAILPFVISNGPSGAPLSFKFAHRGSAEMLRELSMILRNLCQVVPG 668
            .....:       .||:....|...::..||.|:.||..:..|.|.|.|..|...:.|:.:|||.
 Frog   495 PVSLEN-------PHVIDKHQIWVGIVPRGPDGSQLSSSYDRRFSEEYLSSLGKTIGNIARVVPH 552

  Fly   669 GVVCFLPSYEYLDKVYKYLEQSGTLETISGRKSVFREV--SGSAEQLLDNYALAIKRPASYGALL 731
            |::.|.|||..|||..::.::.|....|...|.:|.|.  .||..:::|.|...|:.....||..
 Frog   553 GLLVFFPSYPVLDKSIEFWKERGLSAKIDDVKPMFVEPRGKGSFTEVIDAYYEKIRSANGSGASF 617

  Fly   732 LSVVGGKLSEGLNFADDLGRAVLVVGLPYSNSLSPELRQRMQHLDE-KLGPG------AGNEYYE 789
            |:|..||.||||:|||:.||.|::.|||:...:.|.:..:||.||| :...|      :|.|:|.
 Frog   618 LAVCRGKASEGLDFADNNGRGVIITGLPFPPRMDPRVVLKMQFLDEMRRSQGSAGLYLSGQEWYR 682

  Fly   790 NLCVKAVNQCIGRAVRHIKDYACVYLLDKRFADPKIRGKLPKWISRHIVEANAANGGFGAVQGRT 854
            ....:||||.|||.:||..||..::|.|.||.....|.:||.|:..::    .....||.:....
 Frog   683 QQASRAVNQAIGRVIRHRNDYGAIFLCDHRFNQSDARAQLPSWVRPYV----RTYDNFGHIIRDV 743

  Fly   855 ARFFK 859
            ::||:
 Frog   744 SQFFR 748

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11403	NP_569898.1	DEAD-like_helicase_N	42..>101	CDD:475120	20/59 (34%)
		rad3	187..837	CDD:273169	194/723 (27%)
rtel1	XP_031750114.1	rad3	8..741	CDD:273169	227/906 (25%)
		HN_RTEL1	881..981	CDD:259826
		HN_RTEL1	1028..1128	CDD:259826
		RING_Ubox	1207..1256	CDD:473075