Protein Alignment CG3638 and ttyh3b

DIOPT Version :9

• Sequence 1: NP_726720.3
• Gene: CG3638 / 31071
• FlyBaseID: FBgn0261444
• Length: 1472
• Species: Drosophila melanogaster
• Sequence 2: NP_001032464.1
• Gene: ttyh3b / 798421
• ZFINID: ZDB-GENE-051120-105
• Length: 560
• Species: Danio rerio
• Alignment Length: 610
• Identity: 143/610 - (23%)
• Similarity: 254/610 - (41%)
• Gaps: 139/610 - (22%)

  Fly     4 PSILVKILHSIPHVNYTFRRVNDTFNPDSDVYLESLVILASIPAGLLIGSLLGLLLYLLTRCCDR 68
            |...|.:.|.:||.|..|::.:..|.||...|.:::::|.:.....|...||.||.|....||.|
Zfish     9 PPWWVNLFHRLPHFNLQFQQTSSDFRPDDSDYQKAVLLLGAAALVCLALDLLFLLFYSFWLCCCR 73

  Fly    69 RQR--KPSAQRCQSCSLVIITLMTCAA-IGLGLYGNDDFHNGLLQAFGSGKSVEGLVLTLKRQTE 130
            |:.  .|:|..|.:...|||..:.|:| |.:|.|||             |::.:|:.    |.|.
Zfish    74 RKNHDSPNADCCCTAWCVIIATLVCSAGIAVGFYGN-------------GETCDGVT----RLTY 121

  Fly   131 SIKHDLETRMAGHKVEQLVEK--PHYNQTVVMLLIETSRLVTENT------SRAVASLDSMVHYF 187
            |::|..:| :||  :::||.:  ...|:|::..|::...:.::.|      .:....||.:::..
Zfish   122 SLRHANQT-VAG--IDKLVSESTSSLNETLMEGLVQLETVYSKQTDYLSIVQKLQGQLDELINLM 183

  Fly   188 MKAK-GSENDTSLMGLLQLGEFYESIRWPATLAFLTVLLLLCTVLVIGVARRSRCTLIFFSVSGL 251
            :... .|.||.||..|..:.|.|:..||...|..|...:::|.::::|:.|.||..||.....|:
Zfish   184 LGVPFWSSNDLSLDHLASITEQYDWYRWLGYLGLLLFDVIICLLVLVGLIRNSRSILIGVCFLGV 248

  Fly   252 FCIIICWLLAGVYLASSVAAGDFCMRPHDYMCRQVGMRSPYVD------FLNCGTPR-NRFILRL 309
            ..::|.|...|:..:.:|.|.|||:.|..|:.: |...:..::      :|.|...: |.|..:|
Zfish   249 LTLVISWASLGLEFSFAVGASDFCVSPDSYITK-VTRENAVINQDILQYYLKCSMGQTNPFQQKL 312

  Fly   310 NESRDLVDRARESVEHMQRMSQETYPHI-----DIQRTLNAMDNDLEITLRNLTTLSATLDRRTI 369
            :.|...:...::.|..:.|.:...:|..     ::|..||:    .|::|.:||.|   :|.|::
Zfish   313 SGSHKALVEMQDDVSELLRSAIRDFPKTKSNLEEMQGVLNS----TEVSLHHLTAL---VDCRSL 370

  Fly   370 DMHYEEALRGLCGGGLLGLSLMMVAGLLTSFLLTILVYADSHAWIYLTKRPTLDADKSETAPLFP 434
            .|.|.:||.|||..|:.||..:::...:|:.:.:.:|.:..|.|  .:|| :.:.|..||
Zfish   371 HMDYVQALTGLCYDGVEGLIYLVLFSFVTALMFSSIVCSVPHTW--QSKR-SEEEDGDET----- 427

  Fly   435 ASNAPSASISPTAPL-STGTINRTLLHHQQASSGGGSGTLPGSGGGAGAGGGVGANGHNGVGPYR 498
                 ||::...||. :...::...|:...:|:.|...:||.
Zfish   428 -----SATLGSRAPHDNLYRVHMPSLYSCGSSTYGNEASLPA----------------------- 464

  Fly   499 NGSAGLRQGLASPSSQSSHTSSTATYNNGTTSYHNSHQQHNNHLYSNHYSHSNNHYNNTQHRTNP 563
                            ::||.|.|..                    ..|...|.::...:....|
Zfish   465 ----------------AAHTVSNAPV--------------------TEYMSQNANFQTPRCENTP 493

  Fly   564 AAGAVAAAVGVVSSGQRSPSPPPVY 588
            ..|              ..||||.|
Zfish   494 LIG--------------RESPPPSY 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3638	NP_726720.3	Tweety_N	1..421	CDD:143653	118/440 (27%)
ttyh3b	NP_001032464.1	Tweety	26..430	CDD:282726	116/444 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	415..435		7/30 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	486..560		7/33 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170590161
Domainoid	1	1.000	180	1.000	Domainoid score	I3452
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	141	1.000	Inparanoid score	I4463
OMA	1	1.010	-	-		QHG48395
OrthoDB	1	1.010	-	-		D318605at33208
OrthoFinder	1	1.000	-	-		FOG0000987
OrthoInspector	1	1.000	-	-		mtm6469
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12424
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X806
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	12	11.970