Protein Alignment CG3638 and Ttyh3

DIOPT Version :9

• Sequence 1: NP_726720.3
• Gene: CG3638 / 31071
• FlyBaseID: FBgn0261444
• Length: 1472
• Species: Drosophila melanogaster
• Sequence 2: XP_030110765.1
• Gene: Ttyh3 / 78339
• MGIID: 1925589
• Length: 543
• Species: Mus musculus
• Alignment Length: 433
• Identity: 116/433 - (26%)
• Similarity: 197/433 - (45%)
• Gaps: 81/433 - (18%)

  Fly    41 ILASIPAGLLIGS---------LLGLLLYLLTRCCDRRQRKP--SAQRCQSCSLVIITLMTCAA- 93
            ::..:||.||:|:         ||.||.|....||.||:...  .|..|.:...||||.:.|:|
Mouse    53 VICWVPALLLLGATALACLALDLLFLLFYSFWLCCRRRKTDEHLDADCCCTAWCVIITTLVCSAG 117

  Fly    94 IGLGLYGNDDFHNGLLQAFGS----GKSVEGL-------VLTLKRQTESIKHDLETRMAGHK--- 144
            |.:|.|||.:..:|:.:|..|    .::|.|:       ...|.|..|.....||.::||.:
Mouse   118 IAVGFYGNGETSDGIHRATYSLRHANRTVAGVQDRVWDTAAALNRTAEPNLQSLERQLAGRQEPL 182

  Fly   145 --VEQLVEKPHYNQTVVMLLIETSRLVTENTSRAVASLDSMVHYFMKAKGSENDTSLMGLLQLGE 207
              |::|       ||::..|:..:..:.                |.:..|    .||..|.:..:
Mouse   183 RAVQRL-------QTLLGTLLGYTAAIP----------------FWRNPG----VSLEVLAEQVD 220

  Fly   208 FYESIRWPATLAFLTVLLLLCTVLVIGVARRSRCTLIFFSVSGLFCIIICWLLAGVYLASSVAAG 272
            .|:..||...|..|.:.:::|.::::|:.|.|:..|:...:.|:..::|.|...|:.||.||.:.
Mouse   221 LYDWYRWLGYLGLLLLDVIICLLVLVGLIRSSKGILVGVCLLGVLALVISWGALGLELAVSVGSS 285

  Fly   273 DFCMRPHDYMCRQVGMRS-------PYVDFLNCGTPR--NRFILRLNESR----DLVDRARESVE 324
            |||:.|..::.:.|...|       .|  :|.| :||  |.|..:|:.|.    ::.|...|.:.
Mouse   286 DFCVDPDTFVTKMVEEHSVLSGDILQY--YLAC-SPRATNPFQQKLSGSHKALVEMQDVVAELLR 347

  Fly   325 HMQRMSQETY-PHIDIQRTLNAMDNDLEITLRNLTTLSATLDRRTIDMHYEEALRGLCGGGLLGL 388
            ::.|....|. |.:.:|..||.    .|:.|::||.|   :|.|::.:.|.:||.|.|..|:.||
Mouse   348 NVPREHPATKDPLLRVQEVLNG----TEVNLQHLTAL---VDCRSLHLDYVQALTGFCYDGVEGL 405

  Fly   389 SLMMVAGLLTSFLLTILVYADSHAWIYLTKRPTLDADKSETAP 431
            ..:.:...:|:.:.:.:|.:..|.|  ..||...|..:.||||
Mouse   406 IYLALFSFVTALMFSSIVCSIPHTW--QQKRGPDDDGEEETAP 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3638	NP_726720.3	Tweety_N	1..421	CDD:143653	111/421 (26%)
Ttyh3	XP_030110765.1	Tweety	80..447	CDD:368183	107/406 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845561
Domainoid	1	1.000	170	1.000	Domainoid score	I3757
eggNOG	1	0.900	-	-		E1_KOG4433
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	188	1.000	Inparanoid score	I3894
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48395
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000987
OrthoInspector	1	1.000	-	-		mtm8906
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12424
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2865
SonicParanoid	1	1.000	-	-		X806
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.890