Protein Alignment CG3638 and Ttyh1

DIOPT Version :10

• Sequence 1: NP_726720.3
• Gene: CG3638 / 31071
• FlyBaseID: FBgn0261444
• Length: 1472
• Species: Drosophila melanogaster
• Sequence 2: NP_001001454.2
• Gene: Ttyh1 / 57776
• MGIID: 1889007
• Length: 460
• Species: Mus musculus
• Alignment Length: 487
• Identity: 131/487 - (26%)
• Similarity: 224/487 - (45%)
• Gaps: 75/487 - (15%)

  Fly     3 QPSILVKILHSIPHVNYTFRRVNDTFNPDSDVYLESLVILASIPAGLLIG-SLLGLLLYLLTRCC 66
            :||..|.:||.:|..::..|.|...|.|....|.::|:::|:: |||.:| ||:.:.:||:..||
Mouse     8 RPSAWVHLLHQLPRADFQLRPVPSGFAPRDQEYQQALLLVAAL-AGLGLGLSLIFIAVYLIRFCC 71

  Fly    67 DR------RQRKPSAQRCQSCSLVIITLMTCAAIGLGLYGNDDFHNG-------LLQAFGSGKSV 118
            .|      .:..|....|.:.|.:...|:.||.||:|.|||.:..:|       ||.|..:..::
Mouse    72 CRPPEPHGAKSPPPGGGCVTWSCIAALLVGCAGIGIGFYGNSETSDGVSQLSSALLHANHTLSTI 136

  Fly   119 EGLVL-TLKRQTESIKHDLETRMAGHKVEQLVEKPHYNQTVVMLLIETSRLVTENTSRAVASLDS 182
            :.:|| |::|..|::|.:|.|      :|:::       :|.|.|:..:|........|...|..
Mouse   137 DDVVLETVERLGEAVKTELTT------LEEVL-------SVRMELVAATRGARRQAEAAAQYLQG 188

  Fly   183 MVHYFMKAKGSENDTSLMGLLQLGE---FYESIRWPATLAFLTVLLLLCTVLVIGVARRSRCTLI 244
            :..:    :|..     :..:|:.|   |.|..||.|.:..|.::||:|...::|:|::|:..::
Mouse   189 LAFW----QGVS-----LSPVQVAEDVTFVEEYRWLAYVLLLLLVLLVCLFTLLGLAKQSKWLVV 244

  Fly   245 FFSVSGLFCIIICWLLAGVYLASSVAAGDFCMRPHDYMC----RQVGMRSPYVD--FLNCGTPRN 303
            ..:...|..:::.|...|:..|::|...|||..|..|:.    .:.|:.|..:.  ||......|
Mouse   245 VMTAMSLLVLVLSWGSMGLEAATAVGLSDFCSNPDTYVLNLTQEETGLSSDILSYYFLCNQAVSN 309

  Fly   304 RFILRLNESRDLVDRARESV-EHMQRMSQETYPHID-IQRTLNAMDNDLEITLRNLTTLSATLDR 366
            .|..||.    |..||..|: ..:|.:.:|..|... .|:.|.:::..|.:|.|:...|.|.|..
Mouse   310 PFQQRLT----LSQRALASIHSQLQGLEREAIPQFSAAQKPLLSLEETLNVTERSFHQLVALLHC 370

  Fly   367 RTIDMHYEEALRGLCGGGLLGLSLMMVAGLLTSFLLTILVYADSHAWIYLTKRPTLDADKSETAP 431
            |::...|..||||||...|.||..:|:..||::..|...:.:...||                 .
Mouse   371 RSLHKDYGSALRGLCEDALEGLLFLMLFSLLSAGALATTLCSLPRAW-----------------A 418

  Fly   432 LFPASNAPSA----SISPTAPLSTGTINRTLL 459
            |||..| |:|    |:....||.:|....::|
Mouse   419 LFPPRN-PNALCSGSLPSEPPLQSGACLSSML 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3638	NP_726720.3	Tweety	4..438	CDD:461475	123/459 (27%)
Ttyh1	NP_001001454.2	Tweety	9..424	CDD:461475	123/458 (27%)