Protein Alignment CG3638 and ttyh2l

DIOPT Version :9

• Sequence 1: NP_726720.3
• Gene: CG3638 / 31071
• FlyBaseID: FBgn0261444
• Length: 1472
• Species: Drosophila melanogaster
• Sequence 2: NP_998421.1
• Gene: ttyh2l / 406540
• ZFINID: ZDB-GENE-040426-2394
• Length: 531
• Species: Danio rerio
• Alignment Length: 620
• Identity: 149/620 - (24%)
• Similarity: 234/620 - (37%)
• Gaps: 172/620 - (27%)

  Fly    11 LHSIPHVNYTFRRVNDTFNPDSDVYLESLVILASIPAGLLIGSLLGLLLYLLTRCCDRRQRKPSA 75
            ||:.||:|:.|:.|::||.|:...|.:|||.||.:.|..|...||.|.:||...||.||:.....
Zfish    17 LHNFPHLNFNFQTVDNTFKPEDASYQQSLVFLACVSAVALGLCLLLLSVYLTCLCCCRREEDEEV 81

  Fly    76 QRCQSC----SLVIITLMTCAAIGLGLYGNDDFHNGLLQ-------------AFGS--GKSVEGL 121
            :|..:|    :.||..|:.|:|:|:|.|||.:.::|:.|             ..||  |.|:..:
Zfish    82 KRPDTCCVTWAAVITGLVICSAVGVGFYGNSETNDGVYQLTYSIYNANHTLGGIGSMVGNSLGSM 146

  Fly   122 VLTLKRQTESIKHDLETR------------MAGHKVEQLVEKPHYNQTVVMLLIETSRLVTENTS 174
            .:.||...|.:......|            ||.:.::||...|...:..|.|
Zfish   147 QVGLKEHLERLDEIFSPRGDYTQTLRFMQQMADNIIQQLTAMPETRKVQVDL------------- 198

  Fly   175 RAVASLDSMVHYFMKAKGSENDTSLMGLLQLGEFYESIRWPATLAFLTVLLLLCTVLVIGVARRS 239
            .|:|...:.:.|:                         ||...|..|.:.|::|.:..:.:|::|
Zfish   199 AAIADRTAFIEYY-------------------------RWLTYLLLLILDLVICLLACLALAKQS 238

  Fly   240 RCTLIFFSVSGLFCIIICWLLAGVYLASSVAAGDFCMRPHDYMCRQV--GMRSPYVD-FLNCG-T 300
            |..|....|.|:..:|:.|...|...|::|...|||:.|..|:..|.  .:.|..|. :|.|. :
Zfish   239 RWLLTVIMVCGMLTLIMSWASLGAGTATAVGTSDFCVSPDKYIVNQTKGTLSSDIVHYYLYCSQS 303

  Fly   301 PRNRFILRLNESRDLVDRARESVEHMQRMSQETYPH-----IDIQRTLNAMDNDLEITLRNLTTL 360
            ..|.|...|...:..:...:..|:.:.:.:...:|.     :.|||.||:.:       .||..|
Zfish   304 LPNPFQQSLTIFQRSLTTMQIQVQGLLQFAVVVFPTAEKDLLGIQRLLNSSE-------FNLHQL 361

  Fly   361 SATLDRRTIDMHYEEALRGLCGGGLLGLSLMMVAGLLTSFLLTILVYADSHAWIYLTKRPTLDAD 425
            :|.||.|::...|.|||.|:|..|:.||..:.:..||.:.....|:.|...||:.:..|.....|
Zfish   362 TALLDCRSLHKDYLEALLGVCYDGVEGLLYLCLFSLLAACAFCALLCAVPRAWMLIAIRDRDYDD 426

  Fly   426 KSETAPLFPASNAPSASISPTAPLSTGTINRTLLHH--QQASSGGGSGTLPGSGGGAGAGGGVGA 488
            ..|..|           .:||...:....:|..:|.  ..:||.|...:|
Zfish   427 IDEEDP-----------FNPTRRFNAYNPSRAQVHSFCSYSSSMGSQTSL--------------- 465

  Fly   489 NGHNGVGPYRNGSAGLRQGLASPSSQSSHTSSTATYNNGTTSYHNSHQQHNNHLYSNHYSHSNNH 553
                                 .|..|:  ||||..|.|.:..:..                 |..
Zfish   466 ---------------------QPPLQA--TSSTPEYMNQSMLFER-----------------NPR 490

  Fly   554 YNNTQHRTNPAAGAVAAAVGVVSSGQRSPSPPPVY 588
            |.|               |.::.||    ||||.|
Zfish   491 YEN---------------VPLIGSG----SPPPSY 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3638	NP_726720.3	Tweety_N	1..421	CDD:143653	119/449 (27%)
ttyh2l	NP_998421.1	Tweety	27..417	CDD:282726	113/434 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170590157
Domainoid	1	1.000	180	1.000	Domainoid score	I3452
eggNOG	1	0.900	-	-		E1_KOG4433
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	141	1.000	Inparanoid score	I4463
OMA	1	1.010	-	-		QHG48395
OrthoDB	1	1.010	-	-		D318605at33208
OrthoFinder	1	1.000	-	-		FOG0000987
OrthoInspector	1	1.000	-	-		mtm6469
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12424
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2865
SonicParanoid	1	1.000	-	-		X806
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.900