Protein Alignment CG3638 and Ttyh3

DIOPT Version :9

• Sequence 1: NP_726720.3
• Gene: CG3638 / 31071
• FlyBaseID: FBgn0261444
• Length: 1472
• Species: Drosophila melanogaster
• Sequence 2: XP_038945308.1
• Gene: Ttyh3 / 304315
• RGDID: 1309549
• Length: 536
• Species: Rattus norvegicus
• Alignment Length: 471
• Identity: 118/471 - (25%)
• Similarity: 202/471 - (42%)
• Gaps: 90/471 - (19%)

  Fly     8 VKILHSIPHVNYTFRRVNDTFNPDSDVYLESLVILASIPAGLLIGSLLGLLLYLLTRCCDRRQRK 72
            |.:||.:||.:..:...:..|.|:...|.::|::|.:.....|...||.||.|....||.||:..
  Rat    12 VSLLHRLPHFDLRWEATSSQFRPEDADYQQALLLLGAAALACLALDLLFLLFYSFWLCCRRRKTD 76

  Fly    73 PSAQR---CQSCSLVIITLMTCAAIGLGLYGNDDFHNGLLQAFGS----GKSVEGL-------VL 123
            .....   |.:..::|.||:..|.|.:|.|||.:..:|:.:|..|    .::|.|:       ..
  Rat    77 EHLDADCCCTAWCVIIATLVCSAGIAVGFYGNGETSDGVHRATYSLRHANRTVAGVQDRVWDTAA 141

  Fly   124 TLKRQTESIKHDLETRMAGHKVEQLVEKPHYNQTVVMLLIETSRLVTENTSRAVASLDSMVHY-- 186
            .|.|..|.....||.::||        :|           |..|.|    .|....|.:::.|
  Rat   142 ALNRTAEPNLQSLEKQLAG--------RP-----------EPLRAV----QRLQTLLGTLLGYTA 183

  Fly   187 ---FMKAKGSENDTSLMGLLQLGEFYESIRWPATLAFLTVLLLLCTVLVIGVARRSRCTLIFFSV 248
               |.:..|    .||..|.:..:.|:..||...|..|.:.:::|.::::|:.|.|:..|:....
  Rat   184 AIPFWRNPG----VSLEVLAEQVDLYDWYRWLGYLGLLLLDVIICLLVLVGLIRSSKGILVGSCP 244

  Fly   249 SG-LF-------------CIIICWLLAGVYLASSVAAGDFCMRPHDYMCRQV-------GMRSPY 292
            .| :|             |::....|..:...||    |||:.|..::.:.|       |....|
  Rat   245 GGRIFLRTPGGPGFPLRPCLVTSPFLPSLPQGSS----DFCIDPDTFVTKMVEEYSVLSGDILQY 305

  Fly   293 VDFLNCGTPR--NRFILRLNESR----DLVDRARESVEHMQRMSQETY-PHIDIQRTLNAMDNDL 350
              :|.| :||  |.|..:|:.|.    ::.|...|.::::.|....|. |.:.:|..||.    .
  Rat   306 --YLAC-SPRATNPFQQKLSGSHKALVEMQDVVAELLKNVPREHPATKDPLLRVQEVLNG----T 363

  Fly   351 EITLRNLTTLSATLDRRTIDMHYEEALRGLCGGGLLGLSLMMVAGLLTSFLLTILVYADSHAWIY 415
            |:.|::||.|   :|.|::.:.|.:||.|.|..|:.||..:.:...:|:.:.:.:|.:..|.|
  Rat   364 EVNLQHLTAL---VDCRSLHLDYVQALTGFCYDGVEGLIYLALFSFVTALMFSSIVCSIPHTW-- 423

  Fly   416 LTKRPTLDADKSETAP 431
            ..||...:..:.||||
  Rat   424 QQKRGADEDGEEETAP 439

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3638	NP_726720.3	Tweety_N	1..421	CDD:143653	114/459 (25%)
Ttyh3	XP_038945308.1	Tweety	25..440	CDD:368183	113/458 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166348974
Domainoid	1	1.000	170	1.000	Domainoid score	I3662
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	187	1.000	Inparanoid score	I3821
OMA	1	1.010	-	-		QHG48395
OrthoDB	1	1.010	-	-		D318605at33208
OrthoFinder	1	1.000	-	-		FOG0000987
OrthoInspector	1	1.000	-	-		mtm9152
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12424
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X806
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	12.010