Protein Alignment CG3638 and Ttyh2

DIOPT Version :9

• Sequence 1: NP_726720.3
• Gene: CG3638 / 31071
• FlyBaseID: FBgn0261444
• Length: 1472
• Species: Drosophila melanogaster
• Sequence 2: XP_221081.9
• Gene: Ttyh2 / 287803
• RGDID: 1562969
• Length: 566
• Species: Rattus norvegicus
• Alignment Length: 605
• Identity: 146/605 - (24%)
• Similarity: 235/605 - (38%)
• Gaps: 139/605 - (22%)

  Fly    11 LHSIPHVNYTFRRVNDTFNPDSDVYLESLV---ILASIPAGLLIGSLLGLLLYLLTRCCDRRQRK 72
            |||:||:....:||:.||:|..:.|.|||:   :||:|..||   :|:.|.:||:..||.||...
  Rat    51 LHSVPHLGLRLQRVDSTFSPSDETYQESLLFLGMLAAIGLGL---NLIFLAIYLVCTCCCRRDHT 112

  Fly    73 PSAQRCQSC----SLVIITLMTCAAIGLGLYGNDDFHNGLLQAF----GSGKSVEGLVLTLKRQT 129
            ...::..||    :.|:..|:.|||:|:|.|||.:.::|:.|..    .:..:..|:...:...|
  Rat   113 VQTKQPDSCCVTWTAVMAGLLCCAAVGVGFYGNSETNDGVHQLIYSLDNANHTFSGMDELVSGNT 177

  Fly   130 ESIKHDLETRMAGHKVEQLVEKPHYNQTVVMLLIETSRLVTENTSRAVASLDSMVHYFMKAKGSE 194
            :.:|.|||..:| ...|....:..|.||:..:......:|.:.:...|              ..|
  Rat   178 QKMKVDLEQHLA-RLSEIFAARGDYMQTLKFMQQMAGNIVNQLSGLPV--------------WRE 227

  Fly   195 NDTSLMGLLQLGEFYESIRWPATLAFLTVLLLLCTVLVIGVARRSRCTLIFFSVSGLFCIIICWL 259
            ....|..|.....:.|..||.:.|....:.|::|.|..:|:||||:|.|......|:..:::.|.
  Rat   228 VTEELTALSHQTAYVEHYRWLSYLLLFILDLVICLVTCLGLARRSKCLLASMLCCGILALVLSWA 292

  Fly   260 LAGVYLASSVAAGDFCMRPHDYMCRQVGMRSPYVDFLNCGTPRNRFILRLNESRDLVDRARESVE 324
            ......|::|...||||.|..|:......:        ..:...|:.|..::|:  :...::|:.
  Rat   293 SLAADAAAAVGTSDFCMVPDVYILNNTQNQ--------ISSEVTRYYLHCSQSQ--ISPFQQSLT 347

  Fly   325 HMQRMSQETYPHIDIQRTLN-------AMDNDL---EITLRNLTT----LSATLDRRTIDMHYEE 375
            ..||  ..|...|.:...|.       ..:.||   ::.|.|..|    |:|.||.|.:...|.:
  Rat   348 IFQR--SLTTMQIQVVGLLQFAVPLFPTAEKDLLGIQLLLNNSETSLHQLTAMLDCRGLHKDYLD 410

  Fly   376 ALRGLCGGGLLGLSLMMVAGLLTSFLLTILVYADSHAWIYLTKRPTLDADKSETAPLFPASNAPS 440
            ||.|:|..|:.||..:.:..||.:...:.|..|...||.:...|.....|..:..|..|.:
  Rat   411 ALTGICYDGIEGLLFLGLFSLLAALAFSTLTCAGPRAWKHFINRDRDYDDIDDDDPFNPQA---- 471

  Fly   441 ASISPTAPLSTGTINRTLLHHQQASSGGGSGTLPGSGGGAGAGGGVGANGHNGVGPYRNGSAGLR 505
                           |.:..|..|     .|.|                 |:    :.:.|:||
  Rat   472 ---------------RRIAAHNPA-----RGQL-----------------HS----FCSYSSGL- 494

  Fly   506 QGLASPSSQSSHTSSTATYNNGTTSYHNSHQQHNNH--LYSNHYSHSNNHYNNTQHRTNPAAGAV 568
                  .||.|....|.|.:|...|      ::.|.  |:.     .|..|.|
  Rat   495 ------GSQCSLQPPTQTISNAPVS------EYMNQAILFG-----GNPRYEN------------ 530

  Fly   569 AAAVGVVSSGQRSPSPPPVY 588
               |.::..|    ||||.|
  Rat   531 ---VPLIGRG----SPPPTY 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3638	NP_726720.3	Tweety_N	1..421	CDD:143653	115/434 (26%)
Ttyh2	XP_221081.9	Tweety	61..453	CDD:368183	109/421 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166348976
Domainoid	1	1.000	170	1.000	Domainoid score	I3662
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	187	1.000	Inparanoid score	I3821
OMA	1	1.010	-	-		QHG48395
OrthoDB	1	1.010	-	-		D318605at33208
OrthoFinder	1	1.000	-	-		FOG0000987
OrthoInspector	1	1.000	-	-		mtm9152
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12424
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X806
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	12.010