Protein Alignment CG3638 and Ttyh2

DIOPT Version :10

• Sequence 1: NP_726720.3
• Gene: CG3638 / 31071
• FlyBaseID: FBgn0261444
• Length: 1472
• Species: Drosophila melanogaster
• Sequence 2: NP_001385533.1
• Gene: Ttyh2 / 287803
• RGDID: 1562969
• Length: 532
• Species: Rattus norvegicus
• Alignment Length: 605
• Identity: 146/605 - (24%)
• Similarity: 235/605 - (38%)
• Gaps: 139/605 - (22%)

  Fly    11 LHSIPHVNYTFRRVNDTFNPDSDVYLESLV---ILASIPAGLLIGSLLGLLLYLLTRCCDRRQRK 72
            |||:||:....:||:.||:|..:.|.|||:   :||:|..||   :|:.|.:||:..||.||...
  Rat    17 LHSVPHLGLRLQRVDSTFSPSDETYQESLLFLGMLAAIGLGL---NLIFLAIYLVCTCCCRRDHT 78

  Fly    73 PSAQRCQSC----SLVIITLMTCAAIGLGLYGNDDFHNGLLQAF----GSGKSVEGLVLTLKRQT 129
            ...::..||    :.|:..|:.|||:|:|.|||.:.::|:.|..    .:..:..|:...:...|
  Rat    79 VQTKQPDSCCVTWTAVMAGLLCCAAVGVGFYGNSETNDGVHQLIYSLDNANHTFSGMDELVSGNT 143

  Fly   130 ESIKHDLETRMAGHKVEQLVEKPHYNQTVVMLLIETSRLVTENTSRAVASLDSMVHYFMKAKGSE 194
            :.:|.|||..:| ...|....:..|.||:..:......:|.:.:...|              ..|
  Rat   144 QKMKVDLEQHLA-RLSEIFAARGDYMQTLKFMQQMAGNIVNQLSGLPV--------------WRE 193

  Fly   195 NDTSLMGLLQLGEFYESIRWPATLAFLTVLLLLCTVLVIGVARRSRCTLIFFSVSGLFCIIICWL 259
            ....|..|.....:.|..||.:.|....:.|::|.|..:|:||||:|.|......|:..:::.|.
  Rat   194 VTEELTALSHQTAYVEHYRWLSYLLLFILDLVICLVTCLGLARRSKCLLASMLCCGILALVLSWA 258

  Fly   260 LAGVYLASSVAAGDFCMRPHDYMCRQVGMRSPYVDFLNCGTPRNRFILRLNESRDLVDRARESVE 324
            ......|::|...||||.|..|:......:        ..:...|:.|..::|:  :...::|:.
  Rat   259 SLAADAAAAVGTSDFCMVPDVYILNNTQNQ--------ISSEVTRYYLHCSQSQ--ISPFQQSLT 313

  Fly   325 HMQRMSQETYPHIDIQRTLN-------AMDNDL---EITLRNLTT----LSATLDRRTIDMHYEE 375
            ..||  ..|...|.:...|.       ..:.||   ::.|.|..|    |:|.||.|.:...|.:
  Rat   314 IFQR--SLTTMQIQVVGLLQFAVPLFPTAEKDLLGIQLLLNNSETSLHQLTAMLDCRGLHKDYLD 376

  Fly   376 ALRGLCGGGLLGLSLMMVAGLLTSFLLTILVYADSHAWIYLTKRPTLDADKSETAPLFPASNAPS 440
            ||.|:|..|:.||..:.:..||.:...:.|..|...||.:...|.....|..:..|..|.:
  Rat   377 ALTGICYDGIEGLLFLGLFSLLAALAFSTLTCAGPRAWKHFINRDRDYDDIDDDDPFNPQA---- 437

  Fly   441 ASISPTAPLSTGTINRTLLHHQQASSGGGSGTLPGSGGGAGAGGGVGANGHNGVGPYRNGSAGLR 505
                           |.:..|..|     .|.|                 |:    :.:.|:||
  Rat   438 ---------------RRIAAHNPA-----RGQL-----------------HS----FCSYSSGL- 460

  Fly   506 QGLASPSSQSSHTSSTATYNNGTTSYHNSHQQHNNH--LYSNHYSHSNNHYNNTQHRTNPAAGAV 568
                  .||.|....|.|.:|...|      ::.|.  |:.     .|..|.|
  Rat   461 ------GSQCSLQPPTQTISNAPVS------EYMNQAILFG-----GNPRYEN------------ 496

  Fly   569 AAAVGVVSSGQRSPSPPPVY 588
               |.::..|    ||||.|
  Rat   497 ---VPLIGRG----SPPPTY 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3638	NP_726720.3	Tweety	4..438	CDD:461475	118/451 (26%)
Ttyh2	NP_001385533.1	Tweety	10..436	CDD:461475	117/448 (26%)