Protein Alignment CG3638 and ttyh1

DIOPT Version :9

• Sequence 1: NP_726720.3
• Gene: CG3638 / 31071
• FlyBaseID: FBgn0261444
• Length: 1472
• Species: Drosophila melanogaster
• Sequence 2: XP_009290420.2
• Gene: ttyh1 / 100537642
• ZFINID: ZDB-GENE-100922-257
• Length: 591
• Species: Danio rerio
• Alignment Length: 633
• Identity: 151/633 - (23%)
• Similarity: 248/633 - (39%)
• Gaps: 144/633 - (22%)

  Fly     4 PSILVKILHSIPHVNYTFRRVNDTFNPDSDVYLESLVILASIPAGLLIGSLLGLLLYLLTRCCDR 68
            ||:.|::.|:||.::.|.:..:..|.|||..|.::|::|:|..|..|:.|||.:|.:|:..||..
Zfish    12 PSVWVRLCHAIPRLSLTMQMRDSVFTPDSWEYQQTLLVLSSFSAIALVLSLLVILCFLIHYCCCH 76

  Fly    69 R-----------------------QRKPSAQRCQSCSLVIITLMTCAAIGLGLYGNDDFHNGLLQ 110
            |                       .:|.....|.:...|....:.|.|||:|.|||.:.::|:.|
Zfish    77 RGESGRDAEEEEEDDDASGGHGYSGKKGRGICCVTWVSVAAVTLCCVAIGVGFYGNSEANDGMYQ 141

  Fly   111 AFGS-----------GKSVEGLVLTLKRQTESIKHDLETRMAGHKVEQLVEKP--HYNQTVVMLL 162
            ...|           ...|...:..|:|........:|....|||...:..:.  ..::.||.||
Zfish   142 LTSSLLTANYTLASIDLLVSDTISGLQRSVSGPLTSMEDVFGGHKPALVPTRSCRRLSERVVSLL 206

  Fly   163 IETSRLVTENTSRAVASLDSMVHYFMKAKGSENDTSLMG-------------------------- 201
               |.|....      .|..:...|.:..|||   |::|
Zfish   207 ---SNLTLGR------GLIPIADGFYRTNGSE---SIVGALTPAPPSVAPTLSPSANSIPAPFSP 259

  Fly   202 -----LLQLGEFYESIRWPATLAFLTVLLLLCTVLVIGVARRSRCTLIFFSVSGLFCIIICWLLA 261
                 .|.:.|.|   ||.:.:..|.|.|::|..:::|:|::||..||..:|.....:.:.|...
Zfish   260 GWAANTLMVNEDY---RWLSYVLLLLVDLVVCFFILLGLAKQSRWLLILMTVLAWLSLFMSWGSL 321

  Fly   262 GVYLASSVAAGDFCMRPHDYMCRQVGMR---SPYV--DFLNCGTPRNR-FILRLNESRDLVDRAR 320
            |:...:.||..|||..|:.::.......   ||.|  .:|.|....:. |...|.:|:    ||.
Zfish   322 GLETPTVVALSDFCFDPNTFVLNSTHFNSGTSPEVLDYYLTCSRKMSSPFQQILTQSQ----RAL 382

  Fly   321 ESV-EHMQRMSQETYPHI-DIQRTLNAMDNDLEITLRNLTTLSATLDRRTIDMHYEEALRGLCGG 383
            .|: .|:..:.::..|.. ..:|:|..:...|..|..|...|.|.|:.|.::..|.::|:|||..
Zfish   383 SSIHSHLSSLERDALPRFPKAERSLREVQQILNTTEGNFHQLVALLNCRGLNKDYVDSLKGLCYD 447

  Fly   384 GLLGLSLMMVAGLLTSFLLTILVYADSHAWIYLTKRPTLDADKSETAPLFPASNAPSASISPTAP 448
            |:.||..:.:...|::...|.::.:...||    :....|:|..|        ::.|.|..|
Zfish   448 GMEGLLYLSLYSFLSALAFTAILCSLPGAW----RSFHSDSDDYE--------DSDSESEDP--- 497

  Fly   449 LSTGTINRTLLHHQ---QASSGGGSGTLPGSGGGAGAG-------------GGVGANGHNGVGPY 497
                     ...||   |.::|...|.||......||.             ..|.:||:.|   |
Zfish   498 ---------FTSHQARRQTATGSQRGALPPFYSYQGAAWTPPFSSAPPLPTPNVSSNGNPG---Y 550

  Fly   498 RNGSAGLRQGLASPSSQSSHTSSTATYNNGTTSYHNSHQQHNNHLYSN 545
            .|.....||     |...|::.|..|...|:.|:  |:..|:.:|||:
Zfish   551 ENLPLSDRQ-----SPPPSYSPSMLTGYGGSQSH--SNPSHSRNLYSH 591

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3638	NP_726720.3	Tweety_N	1..421	CDD:143653	117/491 (24%)
ttyh1	XP_009290420.2	Tweety_N	9..480	CDD:325204	117/490 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170590155
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4433
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	141	1.000	Inparanoid score	I4463
OMA	1	1.010	-	-		QHG48395
OrthoDB	1	1.010	-	-		D318605at33208
OrthoFinder	1	1.000	-	-		FOG0000987
OrthoInspector	1	1.000	-	-		mtm6469
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12424
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X806
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	12	11.870