DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11398 and crol

DIOPT Version :9

Sequence 1:	NP_001259122.2	Gene:	CG11398 / 31070	FlyBaseID:	FBgn0040366	Length:	329	Species:	Drosophila melanogaster
Sequence 2:	NP_001245993.1	Gene:	crol / 34592	FlyBaseID:	FBgn0020309	Length:	962	Species:	Drosophila melanogaster

Alignment Length:	270	Identity:	63/270 - (23%)
Similarity:	101/270 - (37%)	Gaps:	60/270 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 ELQFEELNERSQHQQGGSPSFVCRRCPALFLTREELAAHRPTHRYQGGQQTPASEHACDACGRVF 94
            :.:::.:..|..|.:  ...|:|:.|...|.|.::|..|...|  .||..     ..|..|..||
  Fly   231 QFRYQLIVHRRYHSE--RKPFMCQVCGQGFTTSQDLTRHGKIH--IGGPM-----FTCIVCFNVF 286

  Fly    95 QKHNALVDHMNAHNDVRNYPCPECPARFVQRSNRECHL---------------KNVHRKVYL--- 141
            ..:.:|..||..|:..:.:.|..|...|.::.:.:.|.               |...||.::
  Fly   287 ANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNH 351

  Fly   142 ---------HSCPEPGCKKRFQQRRECDQHV-----KTVHQNERNLVCDTCSARFSHPVNYRKHL 192
                     |.|..  |||.|.::.....|.     :|.||      ||.|..:::...:...|:
  Fly   352 VRKHTGETPHRCDI--CKKSFTRKEHYVNHYMWHTGQTPHQ------CDVCGKKYTRKEHLANHM 408

  Fly   193 ASHGSAKSYGCPICGKLFGRPENRDVHLFVHSICKAYICSVCGADYMRRNQLIRHGLASGHHNDP 257
            .||.:...:.|.||||.|.|.|:...|:..|:....:.|..|...:.|:..|:.|
  Fly   409 RSHTNETPFRCEICGKSFSRKEHFTNHILWHTGETPHRCDFCSKTFTRKEHLLNH---------- 463

  Fly   258 IVRQKPQFSP 267
             |||....||
  Fly   464 -VRQHTGESP 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11398	NP_001259122.2	C2H2 Zn finger	52..72	CDD:275368	6/19 (32%)
		C2H2 Zn finger	87..107	CDD:275368	7/19 (37%)
		C2H2 Zn finger	115..136	CDD:275368	5/35 (14%)
		C2H2 Zn finger	144..165	CDD:275368	6/25 (24%)
		C2H2 Zn finger	175..195	CDD:275368	4/19 (21%)
		C2H2 Zn finger	203..223	CDD:275368	9/19 (47%)
		C2H2 Zn finger	231..247	CDD:275368	4/15 (27%)
crol	NP_001245993.1	C2H2 Zn finger	223..243	CDD:275368	1/11 (9%)
		C2H2 Zn finger	251..271	CDD:275368	6/19 (32%)
		C2H2 Zn finger	279..299	CDD:275368	7/19 (37%)
		COG5048	300..723	CDD:227381	43/192 (22%)
		C2H2 Zn finger	307..327	CDD:275368	4/19 (21%)
		C2H2 Zn finger	335..355	CDD:275368	3/19 (16%)
		C2H2 Zn finger	363..383	CDD:275368	6/21 (29%)
		C2H2 Zn finger	391..411	CDD:275368	4/19 (21%)
		C2H2 Zn finger	419..439	CDD:275368	9/19 (47%)
		C2H2 Zn finger	447..467	CDD:275368	7/30 (23%)
		C2H2 Zn finger	475..495	CDD:275368
		C2H2 Zn finger	503..523	CDD:275368
		C2H2 Zn finger	531..551	CDD:275368
		C2H2 Zn finger	559..579	CDD:275368
		C2H2 Zn finger	587..607	CDD:275368
		C2H2 Zn finger	615..636	CDD:275368
		C2H2 Zn finger	644..664	CDD:275368
		C2H2 Zn finger	676..696	CDD:275368
		C2H2 Zn finger	704..722	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446604
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930