DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11398 and CG1529

DIOPT Version :9

Sequence 1:	NP_001259122.2	Gene:	CG11398 / 31070	FlyBaseID:	FBgn0040366	Length:	329	Species:	Drosophila melanogaster
Sequence 2:	NP_001138223.2	Gene:	CG1529 / 33077	FlyBaseID:	FBgn0031144	Length:	512	Species:	Drosophila melanogaster

Alignment Length:	340	Identity:	78/340 - (22%)
Similarity:	130/340 - (38%)	Gaps:	64/340 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 PHTYED--EELSLNT-----------------EELQFEELNERSQHQQGGSPSFVCRRCPALFLT 61
            |..||:  ::||..|                 .:|.:.|.:.||.| ||.|..|:||.|...|..
  Fly   147 PDEYENSQQQLSQGTGSKRRAGLACDQCGKQVYKLPYLEAHIRSVH-QGYSKPFLCRSCDKSFTR 210

  Fly    62 REELAAH-RPTHRYQGGQQTPASEHACDACGRVFQKHNALVDHMNAHNDVRNYPCPECPARFVQR 125
            .|:|.:| |..|......|....:..|:.|.|.:...|||.:|:..|...:.:.|..|....|.|
  Fly   211 YEQLRSHMRNAHPQLEQLQQELRDLICELCNRQYSTKNALGEHLKRHAQRKEHVCEHCGVAKVTR 275

  Fly   126 SNRECHLKNVHRKVYLHSCPEPGCKKRFQQRRECDQHVKTVHQNERNLVCDTCSARF----SHPV 186
            :....||:..:.......|.:  |.:.|:.:....:||:.||:.:|...|..|..:|    |...
  Fly   276 TELLTHLRTHNPTWERFKCEQ--CPQLFRHKSAISRHVRVVHEGQRRFQCGHCEKKFGTHASQVR 338

  Fly   187 NYRKHLASHGSAKS-----YGCPICGKLFGRPENRDVHLFVHSICKAYICSVCGADYMRRNQLIR 246
            :.|.|..|.||.::     :.|..|.|.....:..::||..|...|.         :.:|.:..|
  Fly   339 HERLHTESTGSGEAAEEWPFACIHCQKPCVSRQTLELHLRRHRARKT---------HRKRREHSR 394

  Fly   247 HGLASGHHNDPIVRQKPQFSPALAAKNRSQRSAIDESQDEELQWLKGVDALDSAGYLENSQFSNT 311
            ........:|                 |.|.....|:|.::|:  ||    :.....:.|:.|:.
  Fly   395 ESQEQEQEHD-----------------RDQEQGAREAQQDQLR--KG----EKLRQRDLSRESHR 436

  Fly   312 GKMTAIFAEDENESE 326
            .::|...::..||.:
  Fly   437 NEVTMQTSQRPNECQ 451

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11398	NP_001259122.2	C2H2 Zn finger	52..72	CDD:275368	8/20 (40%)
		C2H2 Zn finger	87..107	CDD:275368	7/19 (37%)
		C2H2 Zn finger	115..136	CDD:275368	6/20 (30%)
		C2H2 Zn finger	144..165	CDD:275368	5/20 (25%)
		C2H2 Zn finger	175..195	CDD:275368	6/23 (26%)
		C2H2 Zn finger	203..223	CDD:275368	5/19 (26%)
		C2H2 Zn finger	231..247	CDD:275368	1/15 (7%)
CG1529	NP_001138223.2	zf-AD	11..79	CDD:285071
		C2H2 Zn finger	171..192	CDD:275368	4/20 (20%)
		zf-C2H2_2	201..>257	CDD:289522	17/55 (31%)
		C2H2 Zn finger	201..222	CDD:275368	8/20 (40%)
		C2H2 Zn finger	237..257	CDD:275368	7/19 (37%)
		C2H2 Zn finger	265..285	CDD:275368	6/19 (32%)
		zf-C2H2_8	268..349	CDD:292531	20/82 (24%)
		C2H2 Zn finger	294..315	CDD:275368	5/22 (23%)
		C2H2 Zn finger	323..343	CDD:275368	5/19 (26%)
		C2H2 Zn finger	360..380	CDD:275368	5/19 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100