DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11398 and CG9609

DIOPT Version :9

Sequence 1:	NP_001259122.2	Gene:	CG11398 / 31070	FlyBaseID:	FBgn0040366	Length:	329	Species:	Drosophila melanogaster
Sequence 2:	NP_573161.1	Gene:	CG9609 / 32663	FlyBaseID:	FBgn0030787	Length:	403	Species:	Drosophila melanogaster

Alignment Length:	368	Identity:	77/368 - (20%)
Similarity:	128/368 - (34%)	Gaps:	91/368 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 ELQFEELNERSQHQQG-GSPSFVCR--RCPALFLTREELAAHRPTH--------RYQGGQQTPA- 82
            |...||..:|...:.. ||..:.|.  :|.|.|...::|..|...|        .|:|..:|.:
  Fly    14 ETALEEFKQRQGRRNSIGSAKYACSMPKCEATFKRLDQLDRHEYHHTGIKKHACSYEGCDKTYSI 78

  Fly    83 ---------SEH-------------ACDACGRVFQKHNALVDHM-NAHNDVRNYPCPECPARFVQ 124
                     |.|             |.:.|.::|...:.:..|| ..|...:.|||.:|.|:|.|
  Fly    79 VTHLKRHLRSTHERPESAAKKTVKCALEECSKMFISVSNMTRHMRETHESPKVYPCSQCSAKFSQ 143

  Fly   125 RSNRECHLKNVHRKVYLHSCPEPGCKKRFQQRRECDQHV-------------------------- 163
            :...:.|....|...|.:||.:  |.:.|.|:.:|..|.
  Fly   144 KLKLKRHEIREHTLEYPYSCSK--CSRGFYQQWQCQSHEPSCKLYECPGCPLQFDKWTLYTKHCR 206

  Fly   164 KTVHQNERNLVCDTCSARFSHPVNYRKHL-ASHGS-------AKSYGC--PICGKLFGRPENRDV 218
            .::|...|: .||.|.:.|..|...::|| ..|..       |.|:.|  ..|||.:....|...
  Fly   207 DSLHGKNRH-KCDRCDSAFDKPSELKRHLEVKHKEAAQTDECATSFTCNEEGCGKSYSYLRNLRQ 270

  Fly   219 HLFVHSICKAYICSV--CGADYMRRNQLIRHGLASGHHNDPIVRQKPQFSPALAAKNRSQRSAID 281
            |:......:.:.|..  ||..:.....|.||.|..  |.|...:::      |.||.:.:....:
  Fly   271 HMLTAHSGRRFECQALDCGRCFSSAQNLARHLLRD--HKDGATKKE------LKAKKKDKSKTGE 327

  Fly   282 ESQDEELQWLKGVDALDSAGYLENSQFSNTGKMTAIFAEDENE 324
            ..:.:.....:..||       ..|:.|...|:..:..:.|::
  Fly   328 GGKTKSTSRKRRRDA-------GRSKHSRLSKLACLQLDKEDD 363

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11398	NP_001259122.2	C2H2 Zn finger	52..72	CDD:275368	6/21 (29%)
		C2H2 Zn finger	87..107	CDD:275368	4/20 (20%)
		C2H2 Zn finger	115..136	CDD:275368	6/20 (30%)
		C2H2 Zn finger	144..165	CDD:275368	6/46 (13%)
		C2H2 Zn finger	175..195	CDD:275368	7/20 (35%)
		C2H2 Zn finger	203..223	CDD:275368	6/21 (29%)
		C2H2 Zn finger	231..247	CDD:275368	4/17 (24%)
CG9609	NP_573161.1	C2H2 Zn finger	40..59	CDD:275368	5/18 (28%)
		zf-C2H2_8	67..150	CDD:292531	18/82 (22%)
		C2H2 Zn finger	67..90	CDD:275368	4/22 (18%)
		C2H2 Zn finger	106..126	CDD:275368	4/19 (21%)
		C2H2 Zn finger	134..155	CDD:275368	6/20 (30%)
		C2H2 Zn finger	188..210	CDD:275368	0/21 (0%)
		C2H2 Zn finger	217..237	CDD:275368	7/19 (37%)
		C2H2 Zn finger	253..276	CDD:275368	6/22 (27%)
		C2H2 Zn finger	283..302	CDD:275368	5/18 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100