DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11398 and CG18262

DIOPT Version :9

Sequence 1:	NP_001259122.2	Gene:	CG11398 / 31070	FlyBaseID:	FBgn0040366	Length:	329	Species:	Drosophila melanogaster
Sequence 2:	NP_572453.1	Gene:	CG18262 / 31745	FlyBaseID:	FBgn0030012	Length:	469	Species:	Drosophila melanogaster

Alignment Length:	271	Identity:	69/271 - (25%)
Similarity:	111/271 - (40%)	Gaps:	43/271 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 NERSQHQQGGSPS-FVCRR--CPALFLTREELAAHRPTHRYQGGQQTPASEHACDACGRVFQKHN 98
            :||:..::.|.|. :.|..  |...|.|..:|..||..|          :...||.||:.|.:..
  Fly   208 SERNSKKRKGPPKVYKCNEEACNQTFRTERDLRGHRWKH----------TGIFCDICGKPFTQSG 262

  Fly    99 ALVDHMNAHNDVRNYPCPECPARFVQR----SNRECHLKNVHRKVYLHSCPEPGCKKRFQQRREC 159
            .::.|...|:.::.:.||||.|.|..:    |:..||...:       .|....|.:..:.|...
  Fly   263 NMMRHRQRHSGIKPHKCPECDATFYTQKELSSHSICHTGRM-------PCICEVCGRPCRDRGVL 320

  Fly   160 DQHVKTVHQNERNLVCDTCSARF--SHPVNYRKHLASHGSAKSYGCPICGKLFGRPENRDVHLFV 222
            ..|::. |..||...|:.|...|  .|.:|.  |..||.:.:.:.|.:||..|.|.:...||..:
  Fly   321 TAHMRR-HTGERPAKCEVCGKAFYSFHDLNV--HAVSHTNLRPFVCDVCGSTFQRKKALRVHKLL 382

  Fly   223 HSICKAYICSVCGADYMRRNQLIRHGLASGHHNDP-----IVRQKPQFSPALAAKNRSQRS---- 278
            ||..:.|.|.:||..:.:...|..|    ...:||     .|:..||.......:.:|..:
  Fly   383 HSEQRKYACKLCGKTFAQSGGLNAH----MRSHDPARVKGAVKPLPQSVTIEVIEGKSPPTTTIT 443

  Fly   279 -AIDESQDEEL 288
             |||.:.:|:|
  Fly   444 MAIDLNVEEQL 454

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11398	NP_001259122.2	C2H2 Zn finger	52..72	CDD:275368	7/21 (33%)
		C2H2 Zn finger	87..107	CDD:275368	6/19 (32%)
		C2H2 Zn finger	115..136	CDD:275368	9/24 (38%)
		C2H2 Zn finger	144..165	CDD:275368	4/20 (20%)
		C2H2 Zn finger	175..195	CDD:275368	6/21 (29%)
		C2H2 Zn finger	203..223	CDD:275368	7/19 (37%)
		C2H2 Zn finger	231..247	CDD:275368	4/15 (27%)
CG18262	NP_572453.1	C2H2 Zn finger	224..246	CDD:275368	7/21 (33%)
		C2H2 Zn finger	251..271	CDD:275368	6/19 (32%)
		COG5048	<256..415	CDD:227381	44/172 (26%)
		zf-H2C2_2	263..288	CDD:290200	8/24 (33%)
		C2H2 Zn finger	279..327	CDD:275368	13/55 (24%)
		zf-H2C2_2	320..342	CDD:290200	6/22 (27%)
		C2H2 Zn finger	335..355	CDD:275368	6/21 (29%)
		C2H2 Zn finger	363..383	CDD:275368	7/19 (37%)
		zf-C2H2	389..411	CDD:278523	6/25 (24%)
		C2H2 Zn finger	391..411	CDD:275368	5/23 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449820
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930