DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11398 and si:ch211-222k6.1

DIOPT Version :9

Sequence 1:	NP_001259122.2	Gene:	CG11398 / 31070	FlyBaseID:	FBgn0040366	Length:	329	Species:	Drosophila melanogaster
Sequence 2:	XP_021324960.1	Gene:	si:ch211-222k6.1 / 100034531	ZFINID:	ZDB-GENE-050208-649	Length:	674	Species:	Danio rerio

Alignment Length:	214	Identity:	67/214 - (31%)
Similarity:	95/214 - (44%)	Gaps:	12/214 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 EELNERSQHQQGGSPSFVCRRCPALFLTREELAAHRPTHRYQGGQQTPASEHACDACGRVFQKHN 98
            |.||:..:...|..| |.|.:|...||.:..|..|...|       |....|.||.||:.|....
Zfish   127 ERLNKHLKIHTGEKP-FTCDQCGKNFLHKGYLTEHIKIH-------TGEKPHTCDQCGKRFAYKG 183

  Fly    99 ALVDHMNAHNDVRNYPCPECPARFVQRSNRECHLKNVHRKVYLHSCPEPGCKKRFQQRRECDQHV 163
            .|.|||..|...|.|.|.:|..||..:.|...|:| :|.....:||.:  |.|:|:.:.....|:
Zfish   184 NLTDHMKVHTGERPYACDQCAKRFKHKGNLIEHVK-IHTGERPYSCDQ--CGKKFKLKHILSDHM 245

  Fly   164 KTVHQNERNLVCDTCSARFSHPVNYRKHLASHGSAKSYGCPICGKLFGRPENRDVHLFVHSICKA 228
            : :|..|:...|:.|...::...|...|:.||...|.:.|..|||.|.:.....|||..||..:.
Zfish   246 R-IHTGEKPFTCEKCGRSYTRKRNLSDHMKSHTGVKLHTCDQCGKSFVKTGVFKVHLRTHSRERP 309

  Fly   229 YICSVCGADYMRRNQLIRH 247
            :.|..||.|::|...|..|
Zfish   310 FNCDQCGKDFLRMGTLKVH 328

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11398	NP_001259122.2	C2H2 Zn finger	52..72	CDD:275368	6/19 (32%)
		C2H2 Zn finger	87..107	CDD:275368	9/19 (47%)
		C2H2 Zn finger	115..136	CDD:275368	7/20 (35%)
		C2H2 Zn finger	144..165	CDD:275368	5/20 (25%)
		C2H2 Zn finger	175..195	CDD:275368	4/19 (21%)
		C2H2 Zn finger	203..223	CDD:275368	8/19 (42%)
		C2H2 Zn finger	231..247	CDD:275368	6/15 (40%)
si:ch211-222k6.1	XP_021324960.1	C2H2 Zn finger	60..80	CDD:275368
		C2H2 Zn finger	88..108	CDD:275368
		C2H2 Zn finger	116..136	CDD:275368	3/8 (38%)
		C2H2 Zn finger	144..164	CDD:275368	6/19 (32%)
		zf-H2C2_2	156..181	CDD:316026	10/31 (32%)
		C2H2 Zn finger	172..192	CDD:275368	9/19 (47%)
		COG5048	196..607	CDD:227381	42/137 (31%)
		C2H2 Zn finger	200..220	CDD:275368	7/20 (35%)
		C2H2 Zn finger	228..248	CDD:275368	5/22 (23%)
		C2H2 Zn finger	256..276	CDD:275368	4/19 (21%)
		C2H2 Zn finger	284..304	CDD:275368	8/19 (42%)
		C2H2 Zn finger	312..332	CDD:275368	7/17 (41%)
		C2H2 Zn finger	340..360	CDD:275368
		C2H2 Zn finger	368..388	CDD:275368
		C2H2 Zn finger	396..416	CDD:275368
		C2H2 Zn finger	424..444	CDD:275368
		C2H2 Zn finger	452..472	CDD:275368
		C2H2 Zn finger	480..500	CDD:275368
		C2H2 Zn finger	508..528	CDD:275368
		C2H2 Zn finger	536..556	CDD:275368
		C2H2 Zn finger	564..584	CDD:275368
		C2H2 Zn finger	592..612	CDD:275368
		C2H2 Zn finger	620..640	CDD:275368
		C2H2 Zn finger	648..666	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910