DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Kirrel1 and dpr3

DIOPT Version :9

Sequence 1:	XP_006232737.1	Gene:	Kirrel1 / 310695	RGDID:	727883	Length:	805	Species:	Rattus norvegicus
Sequence 2:	NP_001014459.2	Gene:	dpr3 / 3346208	FlyBaseID:	FBgn0053516	Length:	522	Species:	Drosophila melanogaster

Alignment Length:	256	Identity:	56/256 - (21%)
Similarity:	92/256 - (35%)	Gaps:	67/256 - (26%)

- Green bases have known domain annotations that are detailed below.

  Rat    59 PADQTVVAGH-RAVLPC-VLLNYSGIVQW--TKDGLALGMGQG-LKAWPRYRVVGSADAGQYNLE 118
            |.:.|...|| .|::.| |...:...|.|  .:|...|.:|.. ..:..|::|..|.|:.::.|.
  Fly   243 PRNITGRTGHTEAIIKCRVDSLHDKSVSWIRKRDLHILTVGTATYTSDKRFQVTESKDSREWTLH 307

  Rat   119 ITDAELSDDASYECQATEAALRSRRAKLTVLIPPEDTR--IDGGPVILLQAGTPYNLTC--RAFN 179
            :......|...||||.......|...:|.::....|.:  |.|.|.:..:||:...|.|  :..:
  Fly   308 VKAPLAKDSGIYECQVNTEPKMSMAFQLNIIEISPDAKAVISGPPDLHFKAGSAIILNCLVQQPS 372

  Rat   180 AKPAATIIWFRDGTQQEGAVTSTELLKDGKRETTISQLLIQPTDLDIGRVFTCRSMNEAIPNGK- 243
            .|....|.|:|                        .:.:|.|.|.|.|:        ..||.|:
  Fly   373 VKDIGPIYWYR------------------------GEHMITPFDADDGQ--------PEIPAGRG 405

  Rat   244 --------ETS-----IELDVHHPPTVTLSIEPQ---TVLEGERVI---------FTCQAT 279
                    :||     .|:|:.......:::|.|   |:....|:.         :|||.|
  Fly   406 EHPQGIPEDTSPNDIMSEVDLQMEFATRIAMESQLGDTLKSRLRISNAQTTDTGNYTCQPT 466

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Kirrel1	XP_006232737.1	I-set	54..148	CDD:254352	24/93 (26%)
		Ig	57..148	CDD:299845	24/93 (26%)
		Ig2_KIRREL3-like	170..251	CDD:143236	17/96 (18%)
		I-set	255..336	CDD:254352	8/37 (22%)
		Ig_2	259..337	CDD:290606	8/33 (24%)
		Ig_2	340..437	CDD:290606
		IG_like	346..437	CDD:214653
		Ig5_KIRREL3	439..536	CDD:143306
		IG_like	451..536	CDD:214653
dpr3	NP_001014459.2	Ig	243..330	CDD:299845	22/86 (26%)
		IG_like	243..329	CDD:214653	22/85 (26%)
		Ig	350..464	CDD:299845	27/145 (19%)
		IG_like	<441..477	CDD:214653	6/26 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810