Protein Alignment HLA-B and mhc1-uaa

DIOPT Version :10

• Sequence 1: XP_054186779.1
• Gene: HLA-B / 3106
• HGNCID: 4932
• Length: 405
• Species: Homo sapiens
• Sequence 2: NP_001106536.1
• Gene: mhc1-uaa / 100127725
• XenbaseID: XB-GENE-5938651
• Length: 350
• Species: Xenopus tropicalis
• Alignment Length: 335
• Identity: 124/335 - (37%)
• Similarity: 190/335 - (56%)
• Gaps: 11/335 - (3%)

Human    68 GSHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRMAPRAPWIEQ-EGPEYWDRET 131
            ||||:||:|||:|....|.|.|...||||:||..|:.||  :.:..|.|.|::| |||||.|.:|
 Frog    20 GSHSLRYYYTAVSDRAFGLPEFSTAGYVDETQIERYSSD--NGKSEPAAQWMKQNEGPEYRDEQT 82

Human   132 QISKTNTQTYRESLRNLRGYYNQSEAGSHTLQRMYGCDVGPDGRLLRGHDQSAYDGKDYIALNED 196
            ||.|.|...::.:::.....:||: :|:|.:|.||||::..||. .||::|..|||::::||:.:
 Frog    83 QILKGNEAVFKHNVKVAMDRFNQT-SGTHIVQSMYGCELREDGS-TRGYEQDGYDGREFLALDTE 145

Human   197 LSSWTAADTAAQITQRKWEA--AREAEQWRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHH 259
            ...:..:...||:|.:||.:  ..|.|:.|.|||.:|:|||:|||..|:..|:|...|...::..
 Frog   146 RWVYVPSMREAQLTTQKWNSPEVNEPERERNYLENICIEWLKRYLGYGQAELERRVRPHVKISDR 210

Human   260 PISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRY 324
            . ||....|.|.|.||||.||.:.|.|:|:|.....|..|..|..|.::|......|...|...|
 Frog   211 Q-SDGNTELHCQAYGFYPREIDVKWVRNGKDDVHSEEAKEILPNPDGSYQLRVTAEVTPKEGDSY 274

Human   325 TCHVQHEGLPKPLTLRWEPSSQSTIPIVGIVAGLAVLAVVVIGAVVATVMCRRKSSGGKGGSYSQ 389
            .|||:|..|.:.|.:.|...::....:|.|:||:.|..:::..|||.....:::.:  |.| |::
 Frog   275 ACHVEHSSLEEKLIVVWPGPNKDGKNMVIIIAGVVVAVLLITAAVVGFAFYKKRKA--KSG-YTE 336

Human   390 AASSDSAQGS 399
            .||:||...|
 Frog   337 TASNDSPASS 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HLA-B	XP_054186779.1	MHC_I	72..246	CDD:395078	71/176 (40%)
		IgC1_MHC_Ia_HLA-B	247..343	CDD:409617	32/95 (34%)
		Ig strand A	251..259	CDD:409617	1/7 (14%)
		Ig strand B	267..276	CDD:409617	4/8 (50%)
		Ig strand C	280..286	CDD:409617	2/5 (40%)
		Ig strand C'	288..291	CDD:409617	1/2 (50%)
		Ig strand D	295..303	CDD:409617	2/7 (29%)
		Ig strand E	306..316	CDD:409617	1/9 (11%)
		Ig strand F	323..330	CDD:409617	4/6 (67%)
		Ig strand G	336..341	CDD:409617	1/4 (25%)
		MHC_I_C	<389..405	CDD:461964	5/11 (45%)
mhc1-uaa	NP_001106536.1	MHC_I	20..197	CDD:471794	75/180 (42%)
		IgC1_CD1	201..291	CDD:409620	30/90 (33%)
		Ig strand A	202..210	CDD:409620	1/7 (14%)
		Ig strand B	215..225	CDD:409620	3/9 (33%)
		Ig strand C	230..236	CDD:409620	2/5 (40%)
		Ig strand C'	238..241	CDD:409620	1/2 (50%)
		Ig strand D	245..253	CDD:409620	2/7 (29%)
		Ig strand E	256..266	CDD:409620	1/9 (11%)
		Ig strand F	273..280	CDD:409620	4/6 (67%)
		Ig strand G	287..290	CDD:409620	1/2 (50%)