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Protein Alignment eIF4E7 and EIF4E2

DIOPT Version :9

Sequence 1:	NP_726718.1	Gene:	eIF4E7 / 31059	FlyBaseID:	FBgn0040368	Length:	429	Species:	Drosophila melanogaster
Sequence 2:	NP_004837.1	Gene:	EIF4E2 / 9470	HGNCID:	3293	Length:	245	Species:	Homo sapiens

Alignment Length:	203	Identity:	67/203 - (33%)
Similarity:	112/203 - (55%)	Gaps:	8/203 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   218 DNSLEFLSLNNKCDDDLTIAAENAELLEVEDPQHPLNNCWTLWYLEN-----DRNKSWEEMLHKV 277
            :||.:......|.:.|...::...:.:.....:|||...:|.||...     ..::|:|:.:.::
Human    21 ENSTQKDGEKEKTERDKNQSSSKRKAVVPGPAEHPLQYNYTFWYSRRTPGRPTSSQSYEQNIKQI 85

  Fly   278 TSFDTVEKFWSLITHIKPPSELMLGSDYSLFKKGIRPMWEDEANVNGGRWVINLTKSAKMALDSF 342
            .:|.:||:||...:|:..|.:|...||:.|||:||:|||||:||.|||:|:|.|.|.   .....
Human    86 GTFASVEQFWRFYSHMVRPGDLTGHSDFHLFKEGIKPMWEDDANKNGGKWIIRLRKG---LASRC 147

  Fly   343 WMDAMLCLIGEACKHSDDLCGVVVNIRGKSNKISIWNADGGNQTTVLEIGRILRKVLRMDNIYVL 407
            |.:.:|.::||.....:::||.||::|.:.:.|||||....:|.|...|...||:||.:....::
Human   148 WENLILAMLGEQFMVGEEICGAVVSVRFQEDIISIWNKTASDQATTARIRDTLRRVLNLPPNTIM 212

  Fly   408 EYQLHKDS 415
            ||:.|.||
Human   213 EYKTHTDS 220

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.