Protein Alignment eIF4E7 and eIF4E1

DIOPT Version :9

• Sequence 1: NP_726718.1
• Gene: eIF4E7 / 31059
• FlyBaseID: FBgn0040368
• Length: 429
• Species: Drosophila melanogaster
• Sequence 2: NP_001261626.1
• Gene: eIF4E1 / 45525
• FlyBaseID: FBgn0015218
• Length: 259
• Species: Drosophila melanogaster
• Alignment Length: 428
• Identity: 159/428 - (37%)
• Similarity: 194/428 - (45%)
• Gaps: 169/428 - (39%)

  Fly     2 LPNSFYRMRDFANPRTMFKSCANNNEYPTQGPQKVESPTDVTQPAAAPQSTEDTQPEKTQEPMND 66
            :.:.|:||::||||::|||:.|.:.|   ||  :.|.||.    ||||...:|.:|::      |
  Fly     1 MQSDFHRMKNFANPKSMFKTSAPSTE---QG--RPEPPTS----AAAPAEAKDVKPKE------D 50

  Fly    67 PNKTSPSEPQKRGKGNRKGKKNQKNAPRTPSQTSKSSRSNNPGKDGKSTGNDDNEKGKGQGKQMV 131
            |.:|                                         |:..||
  Fly    51 PQET-----------------------------------------GEPAGN-------------- 60

  Fly   132 QQKENSPEQEQSTSAQYRKNVLDKDLQDKKLIEKNMQGKIITQENLLGQKVLMRLSEQKLLSLRL 196
                                                                             
  Fly    61 ----------------------------------------------------------------- 60

  Fly   197 EPRIKQNTCPPAKKEDAVVAFDNSLEFLSLNNKCDDDLTIAAENAELLEVEDPQHPLNNCWTLWY 261
                ...|..|| .:|||                         ..|.|.    :|||.|.|||||
  Fly    61 ----TATTTAPA-GDDAV-------------------------RTEHLY----KHPLMNVWTLWY 91

  Fly   262 LENDRNKSWEEMLHKVTSFDTVEKFWSLITHIKPPSELMLGSDYSLFKKGIRPMWEDEANVNGGR 326
            |||||:||||:|.:::|||||||.||||..|||||||:.||||||||||.|||||||.||..|||
  Fly    92 LENDRSKSWEDMQNEITSFDTVEDFWSLYNHIKPPSEIKLGSDYSLFKKNIRPMWEDAANKQGGR 156

  Fly   327 WVINLTKSAKMALDSFWMDAMLCLIGEACKHSDDLCGVVVNIRGKSNKISIWNADGGNQTTVLEI 391
            |||.|.||:|..||:.|:|.:|||||||..|||.:||.|:||||||||||||.|||.|:...|||
  Fly   157 WVITLNKSSKTDLDNLWLDVLLCLIGEAFDHSDQICGAVINIRGKSNKISIWTADGNNEEAALEI 221

  Fly   392 GRILRKVLRMDNIYVLEYQLHKDSKDKLGSTVKRIYTV 429
            |..||..||:.....|:||||||:..|.||.||.|||:
  Fly   222 GHKLRDALRLGRNNSLQYQLHKDTMVKQGSNVKSIYTL 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF4E7	NP_726718.1	IF4E	255..409	CDD:279921	105/153 (69%)
eIF4E1	NP_001261626.1	IF4E	82..239	CDD:366742	107/156 (69%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45470279
Domainoid	1	1.000	143	1.000	Domainoid score	I1494
eggNOG	1	0.900	-	-		E1_COG5053
Homologene	1	1.000	-	-		H123817
Inparanoid	1	1.050	160	1.000	Inparanoid score	I1633
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1394271at2759
OrthoFinder	1	1.000	-	-		FOG0000666
OrthoInspector	1	1.000	-	-		mtm6577
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11960
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R595
SonicParanoid	1	1.000	-	-		X406
	12	11.930