DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eIF4E7 and eif4e2rs1

DIOPT Version :9

Sequence 1:	NP_726718.1	Gene:	eIF4E7 / 31059	FlyBaseID:	FBgn0040368	Length:	429	Species:	Drosophila melanogaster
Sequence 2:	NP_957053.1	Gene:	eif4e2rs1 / 393732	ZFINID:	ZDB-GENE-040426-1728	Length:	228	Species:	Danio rerio

Alignment Length:	223	Identity:	77/223 - (34%)
Similarity:	121/223 - (54%)	Gaps:	27/223 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   209 KKEDA----VVAFDNSLEFLSLNNKCDD----DLTIAAENAELLEVEDPQHPLNNCWTLWYLEND 265
            |:||.    .:..:|..:..|:||..::    .:|.||          .:|||...:|.||....
Zfish     8 KEEDCGDHEEMKDNNESDRASINNNNNNIRRKMVTPAA----------GEHPLQYNYTFWYSRRT 62

  Fly   266 -----RNKSWEEMLHKVTSFDTVEKFWSLITHIKPPSELMLGSDYSLFKKGIRPMWEDEANVNGG 325
                 ..:|:|:.:.::.:..:||:||...:|:..|.:|...||:.|||:||:||||||||.|||
Zfish    63 PSRPANTQSYEQNIRQMGTVASVEQFWKFYSHLVRPGDLTGHSDFHLFKEGIKPMWEDEANKNGG 127

  Fly   326 RWVINLTKSAKMALDSFWMDAMLCLIGEACKHSDDLCGVVVNIRGKSNKISIWNADGGNQTTVLE 390
            :|:|.|.|.   ....||.:.:|.::||.....:::|||||:||.:.:.:||||....:|.|...
Zfish   128 KWIIRLRKG---LASRFWENIILAMLGEQFMVGEEICGVVVSIRFQEDILSIWNKTANDQVTTSR 189

  Fly   391 IGRILRKVLRMDNIYVLEYQLHKDS-KD 417
            |...||:||.:....::||:.|.|| ||
Zfish   190 IRDTLRRVLNLPPNTIMEYKTHNDSLKD 217

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eIF4E7	NP_726718.1	IF4E	255..409	CDD:279921	57/158 (36%)
eif4e2rs1	NP_957053.1	IF4E	52..208	CDD:279921	57/158 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170573592
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1394271at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101698
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.750