DRSC/TRiP Functional Genomics Resources

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Protein Alignment eIF4E7 and eIF4E3

DIOPT Version :9

Sequence 1:NP_726718.1 Gene:eIF4E7 / 31059 FlyBaseID:FBgn0040368 Length:429 Species:Drosophila melanogaster
Sequence 2:NP_648194.1 Gene:eIF4E3 / 38923 FlyBaseID:FBgn0265089 Length:244 Species:Drosophila melanogaster


Alignment Length:227 Identity:99/227 - (43%)
Similarity:143/227 - (62%) Gaps:26/227 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly   215 VAFDNSLEFLSLNNK------------CDDDLTIAAENAELLEVEDPQHPLNNCWTLWYLENDRN 267
            :|..:.||.:|.|.:            .|.||.:             :|||.:.||||:|||||.
  Fly    32 LAVYDGLELMSGNEEELQPSLNRVMKNIDYDLAM-------------KHPLEHTWTLWHLENDRT 83

  Fly   268 KSWEEMLHKVTSFDTVEKFWSLITHIKPPSELMLGSDYSLFKKGIRPMWEDEANVNGGRWVINLT 332
            |.|.|||..||||:|||.|:|:...:||||:|.:.:||.:|||.|||||||:.|.|||||::.|.
  Fly    84 KRWAEMLVDVTSFNTVEDFFSVYYFVKPPSDLKIFNDYMVFKKNIRPMWEDDTNKNGGRWILLLD 148

  Fly   333 KSAKMALDSFWMDAMLCLIGEACKHSDDLCGVVVNIRGKSNKISIWNADGGNQTTVLEIGRILRK 397
            |:::..:|..|.|.:||:|||..:|||::||||:|:|.|:||:|:|..|..|...:|.|||.:::
  Fly   149 KASRTYIDKMWHDLLLCMIGECFQHSDEICGVVINVRNKANKLSLWTKDSRNVEAILSIGRQIKE 213

  Fly   398 VLRMDNIYVLEYQLHKDSKDKLGSTVKRIYTV 429
            :|.: .|..::||:|||:....|..|..|||:
  Fly   214 LLHL-GIMEIQYQVHKDAMVNHGPNVNAIYTL 244

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
eIF4E7NP_726718.1 IF4E 255..409 CDD:279921 78/153 (51%)
eIF4E3NP_648194.1 IF4E 71..224 CDD:279921 78/153 (51%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45470282
Domainoid 1 1.000 143 1.000 Domainoid score I1494
eggNOG 1 0.900 - - E1_COG5053
Homologene 1 1.000 - - H123817
Inparanoid 1 1.050 160 1.000 Inparanoid score I1633
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1394271at2759
OrthoFinder 1 1.000 - - FOG0000666
OrthoInspector 1 1.000 - - mtm6577
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR11960
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X406
1110.900

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