back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment eIF4E7 and EIF4E1B

DIOPT Version :9

Sequence 1:	NP_726718.1	Gene:	eIF4E7 / 31059	FlyBaseID:	FBgn0040368	Length:	429	Species:	Drosophila melanogaster
Sequence 2:	NP_001092878.1	Gene:	EIF4E1B / 253314	HGNCID:	33179	Length:	242	Species:	Homo sapiens

Alignment Length:	208	Identity:	90/208 - (43%)
Similarity:	130/208 - (62%)	Gaps:	10/208 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   224 LSLNNKCDDDLTIAAENAELLEVEDPQHPLNNCWTLWYLENDRNKSWEEMLHKVTSFDTVEKFWS 288
            |||..|        |.....:||:...|||.|.|.||:.:|||:::|::.||.||..||||.||:
Human    43 LSLRGK--------ARTGGPMEVKLELHPLQNRWALWFFKNDRSRAWQDNLHLVTKVDTVEDFWA 99

  Fly   289 LITHIKPPSELMLGSDYSLFKKGIRPMWEDEANVNGGRWVINLTKSAK-MALDSFWMDAMLCLIG 352
            |.:||:..|:|..|.||:|||.||:|||||..|..||||:::|.|..: :.||..|::.:|||||
Human   100 LYSHIQLASKLSSGCDYALFKDGIQPMWEDSRNKRGGRWLVSLAKQQRHIELDRLWLETLLCLIG 164

  Fly   353 EAC-KHSDDLCGVVVNIRGKSNKISIWNADGGNQTTVLEIGRILRKVLRMDNIYVLEYQLHKDSK 416
            |:. :||.::||.|||||.|.:||::|..:..||..||.:||:.::.|.:....::.||.|.|:.
Human   165 ESFEEHSREVCGAVVNIRTKGDKIAVWTREAENQAGVLHVGRVYKERLGLSPKTIIGYQAHADTA 229

  Fly   417 DKLGSTVKRIYTV 429
            .|..|..|..:.|
Human   230 TKSNSLAKNKFVV 242

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.