DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3655 and CG12910

DIOPT Version :9

Sequence 1:	NP_001259118.1	Gene:	CG3655 / 31056	FlyBaseID:	FBgn0040397	Length:	596	Species:	Drosophila melanogaster
Sequence 2:	NP_001260858.1	Gene:	CG12910 / 36082	FlyBaseID:	FBgn0033502	Length:	466	Species:	Drosophila melanogaster

Alignment Length:	457	Identity:	99/457 - (21%)
Similarity:	176/457 - (38%)	Gaps:	109/457 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    94 LPIAYWSKNKNFLQQKSSTCAK--YPSIFE-----LEFNNIYWQTLRTSNGTFQLFGAYYDIRRT 151
            |.:.|.|...:..::.....||  ...|||     .:::| .|:.:..|....:::.||:| .||
  Fly    25 LVLVYISMRSSLNERLREDLAKAQRQMIFERPNPHWDYSN-SWRRIGNSTLRHEIYSAYFD-ART 87

  Fly   152 SLLG-----------PTVRILGMI-DRI-EPKVKTYCQFW-FDGQKEPFIVKTFEYKYIWYNKWG 202
            .::|           .::||..:: :|: :..:....:|. |..|:    :|..|         .
  Fly    88 DIVGNVRMDDEQMTIGSLRIFAILPERLRDSSINCIVRFSDFSSQE----IKAEE---------A 139

  Fly   203 NYKQGIYQPYLIACQIPKPFHGV------VPSSVSMVEKECDTATNNL--------RVIYNRPPD 253
            .....::.....|..|..|.|..      :|.:|::.     .|:|.|        ::.|.|...
  Fly   140 GAMHDVHNNTFAAWSIMCPLHASRRSPLRLPQAVALA-----YASNRLSHLSPTFIQISYPRNMT 199

  Fly   254 D----QKKGFAVCVKGLDFLYDDLSVRLIEWIEMLNILGADKIYFYNLQVHPNITKVLNHYEQEG 314
            :    .:...:|||..|...|.:: :||:|::||..:.||...|||.::....:.:||.||::.|
  Fly   200 NMFGRSRPTISVCVGPLHENYSNV-LRLVEFVEMYRLQGATHFYFYYVEASEEVLRVLEHYQRIG 263

  Fly   315 KVQVIPLTLPGGQPNVPGFQHLYLTKKTNHKRQNEVIPYNDCLYKNLYL--YDYIALLDIDEVIM 377
            ...|....:.....:|    |.          ...|..:|||:|:...:  :.|.|::|:|||:|
  Fly   264 LADVFEWNVQAHMQDV----HY----------AGIVAQFNDCVYRANVVDNFRYAAVVDLDEVVM 314

  Fly   378 PKGGAVLWSELMDKVR--PESRKIKPDGFHSYNFRNVYFLDDQQHEHGWHKDIPKYMHMLQHVHR 440
            |    :..:.|.|.:|  .|.|..      .:.||||:|       |  .:|.....:...||..
  Fly   315 P----LKHNTLADYLRQCDEGRTA------GFVFRNVFF-------H--RRDSNDTFNAPSHVLN 360

  Fly   441 AKNYTKPN---------QYV--KCFHDPERVLTLHNHFPLSCLGGVCKSYPVDTKDAQLQHYRAD 494
            ...||:..         .|:  |...:...::.:.||.......|.. .:.|......|.|||..
  Fly   361 RLLYTQSKVRRTLEVLPAYIRSKVVVNARAIVEMGNHQVYRAAPGYA-DHVVHPTVGLLFHYRDK 424

  Fly   495 CV 496
            |:
  Fly   425 CI 426

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3655	NP_001259118.1	Glyco_transf_92	257..527	CDD:279961	63/255 (25%)
CG12910	NP_001260858.1	Glyco_transf_92	209..423	CDD:279961	61/248 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4735
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D561250at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR21461
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R16972
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.950