DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment su(w[a]) and AT5G55100

DIOPT Version :9

Sequence 1:	NP_476756.2	Gene:	su(w[a]) / 31054	FlyBaseID:	FBgn0003638	Length:	963	Species:	Drosophila melanogaster
Sequence 2:	NP_568820.1	Gene:	AT5G55100 / 835601	AraportID:	AT5G55100	Length:	844	Species:	Arabidopsis thaliana

Alignment Length:	978	Identity:	231/978 - (23%)
Similarity:	347/978 - (35%)	Gaps:	267/978 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 LELLVFGYACKIFRDDEKAREMDHGKQLIPWMGDVNLKIDRYDVRGALCELAPHEAPPGGYGNRL 122
            ::|.:.|.....|.||..|..::....|:.|.   :|.|||||||..|     ...||.....|.
plant     1 MDLEIVGRHALFFDDDSMATFVNSPTALVDWN---SLFIDRYDVRHLL-----SSPPPPRIKRRR 57

  Fly   123 EYLSAEEQRAEQLCEEERYLFLYNNEEELRLRQEEDLKRLQQETSGGCFSQVGFQYDGQSAASTS 187
            .  ::.:...|...:.||||.|.:.........|.|:......|:.          ||..|.|.|
plant    58 P--NSNDADLESELDHERYLDLPSESPSPSDDDEHDMNEDSANTNA----------DGYRAVSFS 110

  Fly   188 IGGSSTATSQLSPNSEESEL--PFVLP-YTLMMAPPLDMQLPETMKQHAIIEKTARFIATQGAQM 249
            .|.||....|.:....||..  ||.:| |       |...||.|.|.|.||.:|:.|::..|.|.
plant   111 YGSSSDVNDQKNAADMESGFHPPFPVPDY-------LRQNLPPTEKLHQIITRTSSFVSKHGGQS 168

  Fly   250 EILIKAKQANNTQFDFLTQGGHLQPYYRHLLAAIKAAKFPPAPQTPLDQQNTDKEAPSADDHSEE 314
            ||:::.||.:|..|.||....||..|:|.|:                             ||.|.
plant   169 EIVLRVKQGDNPTFGFLMPDHHLHLYFRFLV-----------------------------DHQEL 204

  Fly   315 VAGGRRNPNQVVITVPTIKYKPSANCAYTQLISKIKGVPLQAVLQEDESSNPGNSQHSGGTASPA 379
            :.|                 |.|.                      :|..|  .|:..||..|
plant   205 LTG-----------------KSSV----------------------EEKKN--ESEKDGGALS-- 226

  Fly   380 LSCRSEGHNSQGGEFTPVLLQYNGSTF-THEEESSNREQQDDN---------------DVNGGEP 428
                              ||   ||.: |.|:|.:|.|..:|:               |.||.|.
plant   227 ------------------LL---GSVYGTVEDEDANEESANDSKTSESAKGDDGVKVTDSNGPEG 270

  Fly   429 PQ----------VELLKNTSALALAQNYSSESEEEEDQVQPEK---EEEKKPEPVLTFPVPKDSL 480
            .:          :.|..:.|.:....:.|:.:..|:.|:..||   .::.:|:..|....|...:
plant   271 SKGAAKIASKHSLPLNDHASFIKRNPSVSAVNVVEKKQINTEKLVTSDKSQPKLELQIVEPTTEM 335

  Fly   481 RHIIDKTATYVIKNGRQFEETLRTKSV--DRFSFLLPANEYYPYYLYKV--------TGDVDAAS 535
            :.:|||...::.|||::.|.||..:.|  ..|.||.|::.|:.|| .||        :||.....
plant   336 KRVIDKIVDFIQKNGKELEATLVAQDVKYGMFPFLRPSSLYHAYY-RKVLQEAEELKSGDKGVII 399

  Fly   536 KEEKTRKAAAVAAALMSKKGLSFGGAAAAVSGSNLDKAPVSFSIRARDDQCPLQHTLPQEASDEE 600
            ::|..::.....|...||.|  ||......|........||...:......|.:...||...:.:
plant   400 RKEDVKQEKMGNAVKDSKHG--FGSVLPDDSAKKEKLKMVSDKPKVELHNEPFKPVQPQMRVNVD 462

  Fly   601 TSSNAAGVEHVRPGMPDSVQRAIKQVETQLLA-----RTAGQKGNITASPSCSSPQKEQRQAEER 660
            .::.||.::..|        |.|:..:..:|.     .|:...||..:.||..||.
plant   463 ANTAAAILQAAR--------RGIRNPQLGILTGKPMDETSQTLGNDVSYPSSKSPD--------- 510

  Fly   661 VKDKLAQIAREKLNGM------------ISREKQLQLERKRKALAFLNQIKGEGAIVGSAVP--V 711
                ||:...:.|:|.            :|:|::|:.||.::|..|:.::|.:...|..|.|  .
plant   511 ----LAKSTGQSLSGSTAASEADSSEAGLSKEQKLKAERLKRAKMFVAKLKPDAQPVQQAEPSRS 571

  Fly   712 VGPNPPE---SAAGAATADSGDESGDSVRSIPITYFGPDDDDEVGEQRPEMRLIGSTQKDEEDDD 773
            :...|.:   |..||..|...|.|     |||........||...|:|.:......:|:||  |.
plant   572 ISVEPLDSGISGLGAKAAKERDSS-----SIPYVAESKLADDGNSERRSKRNYRSRSQRDE--DG 629

  Fly   774 EEDGGDLEKYNLLNDDSTNTFTSKPVLPPTAAPPPAAVLLSDDDDVQLVATTSTRSSSSRHLKTH 838
            :.:.|:.|:                               |..|:|.....|..:.|.||....|
plant   630 KMEQGEEEE-------------------------------SSMDEVTEETKTDKKHSCSRKRHKH 663

  Fly   839 --------RRSRSRSKNVRSSDSSPSSRESSRRRRQKSS-RLSREPSSNPPRKSQHSSTQRKKT- 893
                    |.||.:.|:..|||....||...|.|..||| |.....||:...:.:|.|::..|.
plant   664 KTRYSSKDRHSRDKHKHESSSDDEYHSRSRHRHRHSKSSDRHELYDSSDNEGEHRHRSSKHSKDV 728

  Fly   894 --PKKRRRSKSRSRSKSIRRSRSISILRNNRRSRSRSPSCRNAEQRRQQDRRRTPTKKSHKRHKR 956
              .|.:|....|||.....|..|.....::|...||         |:.:|.........||..||
plant   729 DYSKDKRSHHHRSRKHEKHRDSSDDEHHHHRHRSSR---------RKHEDSSDVEHGHRHKSSKR 784

  Fly   957 RRR 959
            .::
plant   785 IKK 787

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
su(w[a])	NP_476756.2	DRY_EERY	60..180	CDD:286793	29/119 (24%)
		SWAP	232..284	CDD:197818	20/51 (39%)
		SWAP	481..527	CDD:197818	17/47 (36%)
AT5G55100	NP_568820.1	DRY_EERY	3..113	CDD:286793	34/129 (26%)
		SWAP	151..201	CDD:197818	20/78 (26%)
		SWAP	336..389	CDD:197818	19/53 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	43	1.000	Domainoid score	I4754
eggNOG	1	0.900	-	-		E1_KOG1847
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	142	1.000	Inparanoid score	I1778
OMA	1	1.010	-	-		QHG60281
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006145
OrthoInspector	1	1.000	-	-		oto3769
orthoMCL	1	0.900	-	-		OOG6_105736
Panther	1	1.100	-	-	LDO	PTHR13161
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.870