Protein Alignment su(w[a]) and Sfswap

DIOPT Version :10

• Sequence 1: NP_476756.2
• Gene: su(w[a]) / 31054
• FlyBaseID: FBgn0003638
• Length: 963
• Species: Drosophila melanogaster
• Sequence 2: NP_001365844.1
• Gene: Sfswap / 231769
• MGIID: 101760
• Length: 996
• Species: Mus musculus
• Alignment Length: 1086
• Identity: 316/1086 - (29%)
• Similarity: 466/1086 - (42%)
• Gaps: 281/1086 - (25%)

  Fly     9 AGGGSV-----GGILRRTGQGSGTGSTILGNGNSPGALGAGKVSSSLENHRQPPLELLVFGYACK 68
            ||||..     ||:....|.| |||:    .||.                    :||||||||||
Mouse     4 AGGGRAKPERKGGVKEEAGPG-GTGT----GGNR--------------------VELLVFGYACK 43

  Fly    69 IFRDDEKAREMDHGKQLIPWMGDVNLKIDRYDVRGALCELAPHEAPPGGYGNRLEYLSAEEQRAE 133
            :|||||:|...:.|:.|||||||..:.|||||.||.|.:|:.::|....: ||...||.||.|.|
Mouse    44 LFRDDERALAQEQGQHLIPWMGDPKILIDRYDGRGHLHDLSAYDAEYATW-NRDYQLSEEEARVE 107

  Fly   134 QLCEEERYLFLYNNEEELRLRQEEDLKRLQQE-TSGGCFSQVGFQYDGQSAASTSIGGS-----S 192
            .||:|||||.|:.:..|...||||:.|||.:. ...|.:|.|||.|           ||     |
Mouse   108 ALCDEERYLALHTDLLEEEARQEEEYKRLSEALAEDGNYSAVGFTY-----------GSDYYDPS 161

  Fly   193 TATSQLSP----------NSEESELPFVLPYTLMMAPPLDMQLPETMKQHAIIEKTARFIATQGA 247
            ..|.:..|          |.||:|.||:.|  |.::.|.|::||.|.|.|||||:||.|:..|||
Mouse   162 EPTEEEEPSKQREKNEAENLEENEEPFIAP--LGLSVPSDVELPPTAKMHAIIERTANFVCKQGA 224

  Fly   248 QMEILIKAKQANNTQFDFLTQGGHLQPYYRHLLAAIKAAKFPPAPQTPLDQQNTDKEAPSADDHS 312
            |.||::|||||.|:|||||....:|.|||:.:..|:|..::....::..:::.  |..|::|:..
Mouse   225 QFEIMLKAKQARNSQFDFLRFDHYLNPYYKFIQKAMKEGRYTVLAESKNEEKK--KSGPTSDNEE 287

  Fly   313 E--EVAGGRRNPNQVVITVPTIKYKPSANCAYTQLISKIKGV----PLQAVLQ--EDESSNPGNS 369
            |  |..|...:|:         .:....:....:|:..:|.|    ||.|:::  :.:||.|...
Mouse   288 EDDEEDGSYLHPS---------LFASKKSSRLEELMKPLKVVDPDHPLAALVRKAQADSSAPAPP 343

  Fly   370 QHSGGTASPALSCRSEGHNSQGGEFTPVLLQYNGSTFTHEEESSNREQQDDNDVNGGEPPQVELL 434
            ...|..|.|          ||        ::|...:.......|.....|........||.:::.
Mouse   344 TADGTPAQP----------SQ--------VEYTADSTVAAMYYSYYMLPDGTYCLAPPPPGIDVA 390

  Fly   435 KNTSALALAQNYSSE--------------------SEEEEDQVQPEKEEEKKPEPVLTFPVPKDS 479
            ...|.|......||.                    :.|....|...........||...|.|.|
Mouse   391 TYYSTLPAGVTVSSSPGVTTTVPPPPGTTPPPPPTTAEPSSGVTSTTTTTSALAPVAIIPPPPD- 454

  Fly   480 LRHIIDKTATYVIKNGRQFEETLRTKSVDRFSFLLPANEYYPYYLYKVT--------GDVDAASK 536
            ::.:|||.|.||.:||.:||.::|.|:..||.||.|.::|..||.:|..        |...|||.
Mouse   455 IQPVIDKLAEYVARNGLKFETSVRAKNDQRFEFLQPWHQYNAYYEFKKQFFLQKEGGGSTQAAST 519

  Fly   537 EEKTRKAAAVAAA-----------LMSKKGLSFGGAAAAVSGSNLDK-------APVSFSIRARD 583
            .|:.....||..:           :....|...|...|..|.|.:|.       ||:||:|:|::
Mouse   520 AEEAPTETAVEESGEAGEDGAPEGMAETGGRGSGKKEAGSSKSTVDGKLVKASFAPISFAIKAKE 584

  Fly   584 -DQCPLQHT---LPQEASDEETS----SNAAGVEHVRP-GMPDSVQRAIKQVETQLLARTAGQKG 639
             |..||:..   |..::.::|.|    .:.:.|.:..| ..|.||  |:::.:.||
Mouse   585 NDLLPLEKNRVKLDDDSEEDEESRECQESTSSVANPSPAAAPPSV--AVEEKKPQL--------- 638

  Fly   640 NITASPSCSSPQKEQRQAEERVKDKLAQIAREKL--NGMISREKQLQLERKRKALAFLNQIKGEG 702
                    :..:.|.:||:::::|:||..|||||  ....|:|||||.||||||..||..:|
Mouse   639 --------TQEELEAKQAKQKLEDRLAAAAREKLAQASKESKEKQLQAERKRKAALFLQTLK--- 692

  Fly   703 AIVGSAVPVVGPNP-PESAAGAATADSGDESGDSV--------------RSIPITYFGPDDDDEV 752
                        || ||:..|..     :||...|              |::||....|
Mouse   693 ------------NPLPEAEVGKL-----EESTFGVEDTGVMPCPLLVGGRTLPILEGKP------ 734

  Fly   753 GEQRPEMRLIGSTQKDEEDDDEE-------DGGDLEKYNLLNDDSTNTFT-SKPVLP-------- 801
             .:||..|.....:::|.:..::       ......||:..:...:.:.: :|..||
Mouse   735 -PERPSNRCRDPPREEEREKKKKKHKKRSRTRSRSPKYHSSSKPRSRSHSKAKHSLPSAYRTVRR 798

  Fly   802 --PTAA---------PPPAAVLLSDDDDVQLVATTSTRSS-SSRHLKTHRRSRSRSKNVRSSDSS 854
              |:|:         |..:||..:..:..|..:.:|:..| ||...|..:.|||||::.|....|
Mouse   799 SRPSASPGILSVEPCPSSSAVAAAQQESSQAASASSSFDSWSSFEGKPGKPSRSRSRSPRRRAHS 863

  Fly   855 PSSRESSRRRRQKSSRLSREPSSNP--PRKSQHSSTQRKKTPKKRRRSKSRSRSKSIRRSRSISI 917
            |     .|||.::|...:...|.:|  .||...|.:..:|  ||:|||:||:::|:
Mouse   864 P-----ERRREERSVPTAYRMSGSPGVSRKRTRSRSPHEK--KKKRRSRSRTKAKA--------- 912

  Fly   918 LRNNRRSRSRSPSCRNAEQRRQQDRRRTPTKKSHKRHKRRRRSSSP 963
                 ||:|.||| :.|.||          ..:|..|.   .|.||
Mouse   913 -----RSQSTSPS-KQAAQR----------PSAHSAHS---ASISP 939

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
su(w[a])	NP_476756.2	DRY_EERY	60..180	CDD:462881	63/120 (53%)
		SWAP	232..284	CDD:197818	30/51 (59%)
		SWAP	481..527	CDD:197818	20/45 (44%)
Sfswap	NP_001365844.1	DRY_EERY	35..155	CDD:462881	63/131 (48%)
		SWAP	209..262	CDD:197818	30/52 (58%)
		SWAP	460..507	CDD:197818	20/46 (43%)