Protein Alignment Cdc45 and CDC45

DIOPT Version :10

• Sequence 1: NP_569880.1
• Gene: Cdc45 / 31052
• FlyBaseID: FBgn0026143
• Length: 575
• Species: Drosophila melanogaster
• Sequence 2: NP_189146.1
• Gene: CDC45 / 822101
• AraportID: AT3G25100
• Length: 596
• Species: Arabidopsis thaliana
• Alignment Length: 591
• Identity: 161/591 - (27%)
• Similarity: 282/591 - (47%)
• Gaps: 77/591 - (13%)

  Fly    26 DIDAICASRILQALFKYDHMLYTVVPIMGVTGLKRAYG-------EHQGDVKYVVLVNCGGCVDI 83
            |:|::||.:::..:.:.|.:.|:..|:.....:.:..|       ..:.....::|:|.|...|:
plant    35 DVDSLCALKVITHILESDSIQYSCFPVSSFLEIHKYAGPAGLCSTSLESPPVTILLINWGCHRDL 99

  Fly    84 VELLQPSDDVTFFICDSHRPLDVCNIYSD--RQVCIL--------GDASLEENI-----PAFETI 133
            ..:|:.......|:.|||||:.:.|: ||  .||.:|        ||.:.:.::     .:|:..
plant   100 KLVLKLGPSARVFVVDSHRPIHLHNL-SDYNEQVVVLHTDDDERQGDLAYDFDVLKLANESFQLR 163

  Fly   134 FYDSEGEDEDEDESSDTEQQHDDSGAGESDQEDQAPRSRKLSRLERHEQRILKQRARRQWESERD 198
            ..|: ||:.||:|..:.|.:.||    :.|..|:..:.||:.    ...::.| :.:|.:
plant   164 VEDA-GEESDEEEEDEEEDEEDD----DDDDGDRPSKRRKMG----DGVKVFK-KLKRDY----- 213

  Fly   199 RIMFEYTQFSYYGRSAALMVFELAWKLSKDNMDLLWWAIVGITEQLLLGKIESGAY---TLELEQ 260
                 |...:::|:.:..::|||:..|.|:..:|||.|.|.:|:|.:..::....|   .:||||
plant   214 -----YKMGTFHGKPSGCLLFELSHMLRKNTNELLWLACVSLTDQFVHERLTDERYQAAVMELEQ 273

  Fly   261 -IQS--HVSRLTNKTNDQNTM----SASKITFENDLHLVLYRHWPVTESMRYSRYSSCQLKLWTL 318
             |.|  ::.::|:.|....|.    ..|:|::|.:..|:|.|.|.:.:||..|.|.:.:||.|:.
plant   274 HINSSGNIDKITSVTLKDGTKVRAPDCSRISYEEEPRLMLLREWTLFDSMLCSSYIATKLKTWSD 338

  Fly   319 RGEKRLHELLLEMGLPLVHARQTYGAMDLVLRKEFFSMVERLAEKYDIADIVYGTFTLSYGYRSR 383
            .|.|:|..||..||..|:..:|.:..|.|.::::.....:|...:|.:.|..|.:|...:||.||
plant   339 NGIKKLKLLLARMGFALIECQQKFPYMSLEVKRKMKQEFDRFLPEYGLNDFYYRSFLRLHGYSSR 403

  Fly   384 YAAADYVYALLAIMESV--KKHKTPEDCFLEASDALSRQHKQLLSAGIDQAKLLHAAVFRQVQSS 446
            .:|||.||.:.|::||.  ....:....|.||.||||..:...|.:|:.||..:..|:.||..::
plant   404 VSAADVVYGITALLESFLGSGGSSASKQFGEAYDALSLNNLDKLRSGMQQAIKVQRAILRQGSAA 468

  Fly   447 LEARQVHSAGSFFYYVLQEEH---AFFSYPYALGLLARFLLRGHVATSRARQASDLPLIASCPLN 508
            :.......:|..|.:|..|:.   .:..||.||.....||:    ...|.:.|...|::.:|
plant   469 ITKSGCIRSGRKFRWVKIEDSMDAKYLGYPQALTKFCYFLM----DALREKGARMKPMLCAC--- 526

  Fly   509 ASE--GMCLLVGIVPVREDSPR------NFFGKAFEQAAQKSGVALLQDFFEPAVVQLRQSDLTR 565
            ||:  |..|:||:.    ..||      |.||.||.:|||:|......:.||.:.:.|..|.:..
plant   527 ASQQPGKILVVGVC----GKPRLGAVRGNAFGNAFRKAAQESRADYFHELFESSWIVLDASAVNS 587

  Fly   566 FLDSLT 571
            |:..||
plant   588 FMIRLT 593

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdc45	NP_569880.1	CDC45	19..570	CDD:460663	159/588 (27%)
CDC45	NP_189146.1	CDC45	28..592	CDD:460663	159/588 (27%)