Protein Alignment HLA-A and RT1-CE4

DIOPT Version :9

• Sequence 1: XP_041536702.1
• Gene: HLA-A / 3105
• HGNCID: 4931
• Length: 391
• Species: Homo sapiens
• Sequence 2: NP_001008842.1
• Gene: RT1-CE4 / 414783
• RGDID: 1598234
• Length: 373
• Species: Rattus norvegicus
• Alignment Length: 369
• Identity: 230/369 - (62%)
• Similarity: 277/369 - (75%)
• Gaps: 8/369 - (2%)

Human     1 MAPRTLVLLLSGALALTQTWAGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQR 65
            |||.||:||::.||..|:|.|||||:|||.|:|||||.||||||:|||||||:|||:||||.:.|
  Rat     4 MAPPTLLLLVAAALTPTKTRAGSHSLRYFHTAVSRPGLGEPRFISVGYVDDTEFVRYDSDAENPR 68

Human    66 MEPRAPWIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYGCDVGSDWRF 130
            .||||.|:|:||||||:.:|:..|.:.|.:||||.||||||||||.||||.|||:||::|||...
  Rat    69 YEPRARWMEREGPEYWERQTQIAKRNEQVYRVDLSTLRGYYNQSEGGSHTYQRMHGCELGSDGSL 133

Human   131 LRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAAHVAEQLRAYLEGTCVEWLRRYLEN 195
            ||||.||||||:|||||.|||::|...|.||:.|::||:.|...|:.|.||:..|:||||:|||.
  Rat   134 LRGYMQYAYDGRDYIALNEDLKTWMVKDTAARITRNKWDQAGFGERKRTYLQVECLEWLRKYLEL 198

Human   196 GKETLQRTDAPKTHMTHHAVSDHEATLRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDG 260
            |||||.|:|.||.|:|.|...:...|||||||.||||:||||||.:|||.|||.|||||||||||
  Rat   199 GKETLLRSDPPKVHVTLHPRPEGGVTLRCWALGFYPADITLTWQLNGEDLTQDMELVETRPAGDG 263

Human   261 TFQKWAAVVVPSGQEQRYTCHVQHEGLPKPLTLRWE-----PSSQPTIPIVGIIAGLVLFGAV-I 319
            |||||||||||||:||:|||||:|||||:|||.|||     .|:..|..|......:.:.||| :
  Rat   264 TFQKWAAVVVPSGEEQKYTCHVEHEGLPEPLTQRWEAPPGTDSNMETNVIYVFFGAVAMIGAVAV 328

Human   320 TGAVVAAVMWRRKSSDRKG--GSYSQAASSDSAQGSDVSLTACK 361
            .|||||.|..||:.....|  |.|:.|..|||.|.|||||..|:
  Rat   329 IGAVVAVVRRRRRRKRNTGGKGDYAPAPGSDSCQSSDVSLADCE 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HLA-A	XP_041536702.1	None
RT1-CE4	NP_001008842.1	MHC_I	25..203	CDD:278555	116/177 (66%)
		IgC_MHC_I_alpha3	207..299	CDD:143322	69/91 (76%)
		MHC_I_C	346..371	CDD:284123	13/24 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	135	1.000	Domainoid score	I34987
eggNOG	0	0.000	Not matched by this tool.
HGNC	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H128352
Inparanoid	1	1.050	526	1.000	Inparanoid score	I11335
NCBI	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG42127
OrthoDB	1	1.010	-	-		D134460at9347
OrthoFinder	1	1.000	-	-		FOG0000140
OrthoInspector	1	1.000	-	-		mtm9986
orthoMCL	1	0.900	-	-		OOG6_101351
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X27
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.880