Protein Alignment CG3690 and SV2B

DIOPT Version :9

• Sequence 1: NP_001284764.1
• Gene: CG3690 / 31047
• FlyBaseID: FBgn0040350
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_001309960.1
• Gene: SV2B / 9899
• HGNCID: 16874
• Length: 683
• Species: Homo sapiens
• Alignment Length: 616
• Identity: 136/616 - (22%)
• Similarity: 247/616 - (40%)
• Gaps: 118/616 - (19%)

  Fly    25 QKEAAADFEAAIDAAGFGMFNILLLVAAVPAAMGTVYETSTMSYILPSAECDLKLSLLDKGILNA 89
            :::.|..:|..:|..|.|.|..:|......|.|....|...:|:.|||||.|:.||...||:|..
Human    88 EEQLAHQYETIMDECGHGRFQWILFFVLGLALMADGVEVFVVSFALPSAEKDMCLSSSKKGMLGM 152

  Fly    90 ITYAGMISSAVLWGYLADIKGRRNLLIVGYAADTICVLGGALSQSRIQLMVFKYLGGFCMSGPFA 154
            |.|.||::.|.:.|.|||..||:.:|.:..|.:.......:..|.....:..:.:.|..:.|...
Human   153 IVYLGMMAGAFILGGLADKLGRKRVLSMSLAVNASFASLSSFVQGYGAFLFCRLISGIGIGGALP 217

  Fly   155 VLMTYLTELHGRKHRQRIMMMVGIMFSIATLTLPGLAMLILPE-TWNIQIWT-LSLTSWQFFVAV 217
            ::..|.:|...|:.|...:..:||.:....|....:|..|:|. .|...:.| ....||:.||.|
Human   218 IVFAYFSEFLSREKRGEHLSWLGIFWMTGGLYASAMAWSIIPHYGWGFSMGTNYHFHSWRVFVIV 282

  Fly   218 TALPSLLSFVLFFFFPESPKFLMSKGRNREALDAFKFMYHLNSR---KPKDSFPIKLLANEVIVP 279
            .|||..:|.|...|.||||:||:..|::.||....|.::..|.|   .|:..|.:
Human   283 CALPCTVSMVALKFMPESPRFLLEMGKHDEAWMILKQVHDTNMRAKGTPEKVFTV---------- 337

  Fly   280 VKKHAKDETIPTELKLP---TECVEVQDPENQDSKKSSLRSGFTQLRPLFTK-----------PY 330
                       :.:|.|   .|.:|:     |.|..:..:....:.:.:|.:           ||
Human   338 -----------SNIKTPKQMDEFIEI-----QSSTGTWYQRWLVRFKTIFKQVWDNALYCVMGPY 386

  Fly   331 LGLSLWVYLLNFCVLLGQNTMRLWLPQL--FASINEYENLMS---GESQSTSICNI-LEYSVNR- 388
            ...:|.:.::.|.:......:.:|.|.:  :....||::.|.   ||....:..|. :|..:::
Human   387 RMNTLILAVVWFAMAFSYYGLTVWFPDMIRYFQDEEYKSKMKVFFGEHVYGATINFTMENQIHQH 451

  Fly   389 -----------------------TQSQLEAVTRNDP-----TVECHVIITPSTYTNNLI------ 419
                                   .:...|.||..|.     |:|..:......|.:..|
Human   452 GKLVNDKFTRMYFKHVLFEDTFFDECYFEDVTSTDTYFKNCTIESTIFYNTDLYEHKFINCRFIN 516

  Fly   420 ------------------------VAGAGFVAYM----LAGFLVNLVGVKLIMTSGLLIAAGCSI 456
                                    |:..|.::.:    ::..|::.:|...::...:||:|.|..
Human   517 STFLEQKEGCHMDLEQDNDFLIYLVSFLGSLSVLPGNIISALLMDRIGRLKMIGGSMLISAVCCF 581

  Fly   457 GMYWSSSAASTVALASLF--VTMGSISATSVISASVSLFPTSLRTMIVSLEMMFGRLGSLLGNIF 519
            .:::.:|.::.:....||  .::.:.:|..||  :|.|:||:.|.....:.....:.|::|||..
Human   582 FLFFGNSESAMIGWQCLFCGTSIAAWNALDVI--TVELYPTNQRATAFGILNGLCKFGAILGNTI 644

  Fly   520 FPALMGLGCVPPFLMISAFMLAGCFMAAFLP 550
            |.:.:|:..|.|.|:.:|.::.|..:|..||
Human   645 FASFVGITKVVPILLAAASLVGGGLIALRLP 675

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3690	NP_001284764.1	SP	42..549	CDD:273317	130/596 (22%)
		MFS	49..>195	CDD:119392	39/145 (27%)
		MFS	419..>550	CDD:119392	32/166 (19%)
SV2B	NP_001309960.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..42
		Sugar_tr	8..683	CDD:331684	136/616 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S5645
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D724235at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8480
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.870