Protein Alignment CG3690 and SLC22A13

DIOPT Version :9

• Sequence 1: NP_001284764.1
• Gene: CG3690 / 31047
• FlyBaseID: FBgn0040350
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_004247.2
• Gene: SLC22A13 / 9390
• HGNCID: 8494
• Length: 551
• Species: Homo sapiens
• Alignment Length: 520
• Identity: 109/520 - (20%)
• Similarity: 182/520 - (35%)
• Gaps: 134/520 - (25%)

  Fly    54 PAAMGTVYETSTMSYILPSAE------CDLKLSLLDKGILNAITYAGMISSAVLWGYLADIKGRR 112
            |..||..|..:.    |||.:      ||.|..   |....::..||::...:::|.|.|..||:
Human   108 PCDMGWEYPENR----LPSLKNEFNLVCDRKHL---KDTTQSVFMAGLLVGTLMFGPLCDRIGRK 165

  Fly   113 NLLIVGYAADTICVLGGALSQSRIQLMVFKYLGGFCMSGPFAVLMTYLTELHGRKHRQRIMMMVG 177
            ..::......|:..|..|...|....|..::.....::|.....:|.|||..|...|.:.:::..
Human   166 ATILAQLLLFTLIGLATAFVPSFELYMALRFAVATAVAGLSFSNVTLLTEWVGPSWRTQAVVLAQ 230

  Fly   178 IMFSIATLTLPGLAMLILPETWNIQIWTLSLTSWQFFVAVTALPSLLSFVLFFFFPESPKFLMSK 242
            ..||:..:.|.|||              ....:|:........|.||.|..|:..|||.::|:::
Human   231 CNFSLGQMVLAGLA--------------YGFRNWRLLQITGTAPGLLLFFYFWALPESARWLLTR 281

  Fly   243 GRNREALDAFKFMYHLNSRK--PKDSFPIKLLANEVIVPVKKHAKDETIPTELKLPTECVEVQDP 305
            ||..||:...:....:|.||  |:       |.|:::                           |
Human   282 GRMDEAIQLIQKAASVNRRKLSPE-------LMNQLV---------------------------P 312

  Fly   306 ENQDSKKSSLRSGFTQLRPLFTKPYLGLSLWVYLLNFCVLLGQNTMRLWLPQLFASINEYE-NLM 369
            |......::|        .||..|.|..   |.|:.|||         |...   |:..|. :|.
Human   313 EKTGPSGNAL--------DLFRHPQLRK---VTLIIFCV---------WFVD---SLGYYGLSLQ 354

  Fly   370 SGESQSTSICNILEYSVNRTQSQLEAVTRNDPTVECHVIITPSTYTNNLIVAGAGFVAYMLAGFL 434
            .|           ::.::                         .|...||.......|...:.|:
Human   355 VG-----------DFGLD-------------------------VYLTQLIFGAVEVPARCSSIFM 383

  Fly   435 VNLVGVKLIMTSGLLIAAG--CSIGMYWSSSAASTVALASLFVTMGSISATSVISA-SVSLFPTS 496
            :...|.|.... |.|:..|  |.|.::..:.....|.:.::...|.:.:|.::... |..||||.
Human   384 MQRFGRKWSQL-GTLVLGGLMCIIIIFIPADLPVVVTMLAVVGKMATAAAFTISYVYSAELFPTI 447

  Fly   497 LRTMIVSLEMMFGRLGSLLGNIFFPALMGLG---CVPPFLMISAFMLAGCFMAAFLPLKNKAALK 558
            ||...:.|..:|.|:|.:|    .|.::.||   ...|.|:..:..:....:...||..:...||
Human   448 LRQTGMGLVGIFSRIGGIL----TPLVILLGEYHAALPMLIYGSLPIVAGLLCTLLPETHGQGLK 508

  Fly   559  558
            Human   509  508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3690	NP_001284764.1	SP	42..549	CDD:273317	105/509 (21%)
		MFS	49..>195	CDD:119392	36/146 (25%)
		MFS	419..>550	CDD:119392	30/136 (22%)
SLC22A13	NP_004247.2	2A0119	12..510	CDD:273328	109/520 (21%)
		MFS	139..500	CDD:119392	94/472 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	511..551

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153554
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840