Protein Alignment CG3690 and SLC22A14

DIOPT Version :9

• Sequence 1: NP_001284764.1
• Gene: CG3690 / 31047
• FlyBaseID: FBgn0040350
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: XP_006713479.2
• Gene: SLC22A14 / 9389
• HGNCID: 8495
• Length: 675
• Species: Homo sapiens
• Alignment Length: 557
• Identity: 116/557 - (20%)
• Similarity: 205/557 - (36%)
• Gaps: 144/557 - (25%)

  Fly    11 KPHKTAEHQIGDPPQKEAAADFEAAIDAAGFGMFNILLLVAAVPAAMGTVY-------ETSTMSY 68
            ||:......:...|....|......|..|..|.|....:...||..:.::.       :|....:
Human   176 KPYCNTSWILAVGPHLSKAEQLNLTIPQAPNGSFLTCFMYLPVPWNLDSIIQFGLNDTDTCQDGW 240

  Fly    69 ILPSAECDLKLSLLD-----------KGILNAITYAGMISSAVLWGYLADIKGRRNLLIVGYAAD 122
            |.|.|:   |.||::           |.....:..||:...::::..:.|..||       |.|.
Human   241 IYPDAK---KRSLINEFDLVCGMETKKDTAQIMFMAGLPIGSLIFRLITDKMGR-------YPAI 295

  Fly   123 TICVLG------GALSQSRIQLMVFKYLG------GFCMSGPFAVLMTYLTELHGRKHRQRIMMM 175
            .:.:||      |....:...|.:|...|      |:.:|.     ::..||....:||...:::
Human   296 LLSLLGLIIFGFGTAFMNSFHLYLFFRFGISQSVVGYAISS-----ISLATEWLVGEHRAHAIIL 355

  Fly   176 VGIMFSIATLTLPGLAMLILPETWNIQIWTLSLTSWQ--FFVAVTALPSLLSFVLFFFFPESPKF 238
            ....|::..:.|.|:|              .||..||  |.|....:...:|::  :..||||::
Human   356 GHCFFAVGAVLLTGIA--------------YSLPHWQLLFLVGGILVIPFISYI--WILPESPRW 404

  Fly   239 LMSKGRNREALDAFKFMYHLNSRKPKDSFPIKLLANEVIVPVKKHAKDETIPTELKLPTECVEVQ 303
            ||.||:.:||.....:...:|.:                          |||:.|     ..|:|
Human   405 LMMKGKVKEAKQVLCYAASVNKK--------------------------TIPSNL-----LDELQ 438

  Fly   304 DPENQDSKKSSLRSGFTQLRPLFTKPYLGLSLWVYLLNFCVLLGQNTMRLWLPQLFASINEYENL 368
            .|..:.::.|.|  .|.:.|.|.....:...:|     |.|.....|:.|.:.:|..|:: :.::
Human   439 LPRKKVTRASVL--DFCKNRQLCKVTLVMSCVW-----FTVSYTYFTLSLRMRELGVSVH-FRHV 495

  Fly   369 MSG--ESQSTSICNILEYSVNRTQSQLEAVTRNDPTVECHVII---------------TPSTYTN 416
            :..  |..:...|..|...:.|..|.  |||.....:.|.:::               .|:|...
Human   496 VPSIMEVPARLCCIFLLQQIGRKWSL--AVTLLQAIIWCLLLLFLPEGEDGLRLKWPRCPATELK 558

  Fly   417 NLIVAGAGFVAYMLAGF-LVNLVGVKLIMTSGLL--IAAGCSIGMYWSSSAASTVALASLFVTMG 478
            ::.:     :..||..| |...|.|..:.|:.||  :.....:|:         |:|||:   .|
Human   559 SMTI-----LVLMLREFSLAATVTVFFLYTAELLPTVLRATGLGL---------VSLASV---AG 606

  Fly   479 SISATSVISASVSLFPTSLRTMIVSLEMMFGRLGSLL 515
            :|.:.::||.:.||.|..|..:   |.::...|.|||
Human   607 AILSLTIISQTPSLLPIFLCCV---LAIVAFSLSSLL 640

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3690	NP_001284764.1	SP	42..549	CDD:273317	110/526 (21%)
		MFS	49..>195	CDD:119392	33/175 (19%)
		MFS	419..>550	CDD:119392	27/100 (27%)
SLC22A14	XP_006713479.2	2A0119	141..650	CDD:273328	116/557 (21%)
		MFS	270..641	CDD:119392	98/460 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153602
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840