DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3690 and NiaP

DIOPT Version :9

Sequence 1:	NP_001284764.1	Gene:	CG3690 / 31047	FlyBaseID:	FBgn0040350	Length:	558	Species:	Drosophila melanogaster
Sequence 2:	NP_001326466.1	Gene:	NiaP / 820491	AraportID:	AT3G13050	Length:	500	Species:	Arabidopsis thaliana

Alignment Length:	540	Identity:	134/540 - (24%)
Similarity:	228/540 - (42%)	Gaps:	98/540 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 EAAIDAAGFGMFNILLLVAAVPAAMGTVYETSTM---SYILPSAECDLKLSLLDKGILNAITYAG 94
            :.|:.|.|||.|.|.:|..   |.||.|.|...|   |::.|:.:....||...:.::.::.:||
plant    11 DEALVAMGFGKFQIYVLAY---AGMGWVAEAMEMMLLSFVGPAVQSLWNLSARQESLITSVVFAG 72

  Fly    95 MISSAVLWGYLADIKGRRNLLIVGYAADTICVLGGALSQSRIQLMVFKYLGGFCMSGPFAVLMTY 159
            |:..|..||.::|..|||...|:......:.....|.|.:.:.|::.:.|.|..:.|. .||.::
plant    73 MLIGAYSWGIVSDKHGRRKGFIITAVVTFVAGFLSAFSPNYMWLIILRCLVGLGLGGG-PVLASW 136

  Fly   160 LTELHGRKHRQRIMMMVGIMFSIATLTLPGLAMLILPETWNIQIWTLSLTSWQFFVAVTALPSLL 224
            ..|......|...|::....:::.|:....||.|::|.           ..|::.:|.:::||.|
plant   137 YLEFIPAPSRGTWMVVFSAFWTVGTIFEASLAWLVMPR-----------LGWRWLLAFSSVPSSL 190

  Fly   225 SFVLFFFFPESPKFLMSKGRNREALDAFKFMYHLNSRKPKDSFPIKLLANEVIVPVKKHAKDETI 289
            ..:.:.:..|||::|:.:||..|||...:.:..:|    |...|..:|::|:...::   :::.|
plant   191 LLLFYRWTSESPRYLILQGRKAEALAILEKIARMN----KTQLPPGVLSSELETELE---ENKNI 248

  Fly   290 PTE----LKL--PTECVEVQDPENQDSK---KSSLRSGFTQLRPLFTKPYLGLSLWVYLLNFCVL 345
            |||    ||.  ..|.|.|       ||   |:....||:.|..|  .|               .
plant   249 PTENTHLLKAGESGEAVAV-------SKIVLKADKEPGFSLLALL--SP---------------T 289

  Fly   346 LGQNTMRLWLPQLFASINEYEN--LMSGESQSTSICNILEYSVNR---TQSQLEAVTRNDPTVEC 405
            |.:.|:.||: ..|.:...|..  |::.|         |..|.||   |:.||    ||...|
plant   290 LMKRTLLLWV-VFFGNAFAYYGVVLLTTE---------LNNSHNRCYPTEKQL----RNSNDV-- 338

  Fly   406 HVIITPSTYTNNLIVAGAGFVAYMLAGFLVNLVGVKLIMTSGLLIAAGCSIGMYWSSSAASTVAL 470
                   .|.:..|.:.|.|...:::..:|:.:|.|..|.|.|...  |...:...|..:..:..
plant   339 -------NYRDVFIASFAEFPGLLISAAMVDRLGRKASMASMLFTC--CIFLLPLLSHQSPFITT 394

  Fly   471 ASLFVTMGSISA--TSVISASVSLFPTSLRTMIVSLEMMFGRLGSLLGNIFFPALMGL--GC--- 528
            ..||.....|||  |.|...:..::||::||..|.:....||:|.:|..:   ..:||  ||
plant   395 VLLFGGRICISAAFTVVYIYAPEIYPTAVRTTGVGVGSSVGRIGGILCPL---VAVGLVHGCHQT 456

  Fly   529 VPPFLMISAFMLAGCFMAAF 548
            :...|.....:::|..:..|
plant   457 IAVLLFEVVILVSGICVCLF 476

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3690	NP_001284764.1	SP	42..549	CDD:273317	130/531 (24%)
		MFS	49..>195	CDD:119392	37/148 (25%)
		MFS	419..>550	CDD:119392	34/137 (25%)
NiaP	NP_001326466.1	MFS	27..476	CDD:421695	126/522 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010