DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3690 and slc22a7a

DIOPT Version :9

Sequence 1:	NP_001284764.1	Gene:	CG3690 / 31047	FlyBaseID:	FBgn0040350	Length:	558	Species:	Drosophila melanogaster
Sequence 2:	NP_001077330.1	Gene:	slc22a7a / 794188	ZFINID:	ZDB-GENE-050506-52	Length:	560	Species:	Danio rerio

Alignment Length:	517	Identity:	112/517 - (21%)
Similarity:	188/517 - (36%)	Gaps:	146/517 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 AVPAAMGTVYE----TSTMSYILPSAECDLKLSLLDKGILN----AITYAGMISSAVLWGYLADI 108
            :||...|.||:    |||     .:.|.||   :.|...||    ...:.|:...||::|.|:|.
Zfish   113 SVPCQNGWVYDRSQFTST-----TATEWDL---VCDNKKLNQALATFFFIGVTMGAVVFGQLSDK 169

  Fly   109 KGRRNLLIVGYAADTICVLGGALSQSRIQLMVFKYLGGFCMSGPFAVLMTYLTELHGRKHRQRIM 173
            .||:.::.|.:.:..:..:..|.|.|.:...:.:.|.||.::|.....:....|....|||....
Zfish   170 FGRKPMIQVSFVSSAVFGIIEAFSSSYVMFAIARTLCGFALTGMSITTVALCVEWTDVKHRTFTG 234

  Fly   174 MMVGIMFSIATLTLPGLAMLILPETWNIQIWTLSLTSWQFFVAVTALPSLLSFVLFFFFPESPKF 238
            .::.:.:|:..:.|..||.||              ..|:..:.|...|.|:..:.:::.|||.::
Zfish   235 TIISLGWSVGNMLLALLAYLI--------------RDWRHLILVVTSPCLVGIIAWWWIPESARW 285

  Fly   239 LMSKGRNREALDAFKFMYHLNSRKPKDSFPIKL-LANEVIVPV-----KKHAKDETIPTELKLPT 297
            |::.||..||.   |::.:......|.|:..|| :.|...:.:     |.|:..:.:.|. ||
Zfish   286 LLANGRVEEAQ---KYLINCAKMNGKYSYTKKLDIENLKKITIAEDSNKNHSYLDLVRTP-KL-- 344

  Fly   298 ECVEVQDPENQDSKKSSLRSGFTQLRPLFTKPYLGLS-------LWVYLLNFCVLLGQNTMRLWL 355
                         :|..|.||.......||  |.|:|       |.:||..|
Zfish   345 -------------RKIVLCSGIFWFAVAFT--YYGISFNITGFGLNIYLTQF------------- 381

  Fly   356 PQLFASINEYENLMSGESQSTSICNILEYSVN-RTQSQLEAVTRNDPTVECHVIITPSTYTNNLI 419
                                  |..::|.... .|...|:.:.|.:....            :||
Zfish   382 ----------------------IYGVIEVPAKVGTYLTLDRIGRRNGQAW------------SLI 412

  Fly   420 VAGAGFVAYMLAGFLVNLVGV-KLIMTSGLLIAAGCSIGMYWSSSAASTVALASLFVTMGSISAT 483
            :|||             |:|: .:|.|....:..|.::.....|.||.|:|.  |:.:
Zfish   413 IAGA-------------LIGLNSVIPTEFAAVRTGIAVIGKGFSEAAFTIAF--LYTS------- 455

  Fly   484 SVISASVSLFPTSLRTMIVSLEMMFGRLGSLLGN--IFFPALMGLGCVPPFLMISAFMLAGC 543
                   .|:||.||...:.......|:|..|..  |.|..:...|  ||.:..:..:.:||
Zfish   456 -------ELYPTVLRQCGLGYTSFIARIGGSLAPMVILFEDIWHYG--PPVVFSATAVFSGC 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3690	NP_001284764.1	SP	42..549	CDD:273317	112/517 (22%)
		MFS	49..>195	CDD:119392	39/150 (26%)
		MFS	419..>550	CDD:119392	30/128 (23%)
slc22a7a	NP_001077330.1	2A0119	11..523	CDD:273328	112/517 (22%)
slc22a7a	NP_001077330.1	MFS	148..514	CDD:119392	98/474 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170588844
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840