Protein Alignment CG3690 and SLC22A5

DIOPT Version :9

• Sequence 1: NP_001284764.1
• Gene: CG3690 / 31047
• FlyBaseID: FBgn0040350
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_001295051.1
• Gene: SLC22A5 / 6584
• HGNCID: 10969
• Length: 581
• Species: Homo sapiens
• Alignment Length: 472
• Identity: 94/472 - (19%)
• Similarity: 169/472 - (35%)
• Gaps: 118/472 - (25%)

  Fly    89 AITYAGMISSAVLWGYLADIKGRRNLLIVGYAADTICVLGGALSQSRIQLMVFKYLGGFCMSGPF 153
            ::.:.|::..:.:.|.|:|..||:|:|.|.....|........|::....:|...|.|......:
Human   171 SLFFVGVLLGSFISGQLSDRFGRKNVLFVTMGMQTGFSFLQIFSKNFEMFVVLFVLVGMGQISNY 235

  Fly   154 AVLMTYLTELHGRKHRQRIMMMVGIMFS-IATLTLPGLAMLILPETWNIQIWTLSLTSWQFFVAV 217
            .......||:.|:.        |.|:|| :..........::||      ::...:..|:..:..
Human   236 VAAFVLGTEILGKS--------VRIIFSTLGVCIFYAFGYMVLP------LFAYFIRDWRMLLVA 286

  Fly   218 TALPSLLSFVLFFFFPESPKFLMSKGRNREALDAFKFMYHLNSRKPKDSFPIKLLANEVIVPVKK 282
            ..:|.:|...|::|.||||::|:|:||..||                          |||:....
Human   287 LTMPGVLCVALWWFIPESPRWLISQGRFEEA--------------------------EVIIRKAA 325

  Fly   283 HAKDETIPTELKLPTECVEVQDPENQDSKKSSLRSGFTQLRP--LFTKPYLGLSLWVYLLNFCVL 345
            .|....:|:.:..|:   |:||   ..|||....:....||.  :.....:.:.||:     .:.
Human   326 KANGIVVPSTIFDPS---ELQD---LSSKKQQSHNILDLLRTWNIRMVTIMSIMLWM-----TIS 379

  Fly   346 LGQNTMRLWLPQLFASINEYENLMSGESQSTSICNILEYSVNRTQSQLEAVTRNDPTVECHVIIT 410
            :|...:.|..|.|...|
Human   380 VGYFGLSLDTPNLHGDI------------------------------------------------ 396

  Fly   411 PSTYTNNLIVAGAGFVAYMLAGFLVNLVGVKLIMTSGLLIAAGCSIGMYWSSSAASTVALASLFV 475
               :.|..:.|.....||:||..|:..:..:..|.:.|.:  |.|:.::..........||::.|
Human   397 ---FVNCFLSAMVEVPAYVLAWLLLQYLPRRYSMATALFL--GGSVLLFMQLVPPDLYYLATVLV 456

  Fly   476 TMGSISATSVISA----SVSLFPTSLRTMIVSLEMMFGRLGSLLGNIFFPALMGLGCVP---PFL 533
            .:|....|:..|.    :..|:||.:|.|.|.:.....||||:|.    |..:.||...   |::
Human   457 MVGKFGVTAAFSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILS----PYFVYLGAYDRFLPYI 517

  Fly   534 MISAFMLAGCFMAAFLP 550
            ::.:..:....:..|||
Human   518 LMGSLTILTAILTLFLP 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3690	NP_001284764.1	SP	42..549	CDD:273317	91/469 (19%)
		MFS	49..>195	CDD:119392	21/106 (20%)
		MFS	419..>550	CDD:119392	32/137 (23%)
SLC22A5	NP_001295051.1	2A0119	12..544	CDD:273328	94/472 (20%)
		MFS	162..534	CDD:119392	92/470 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153573
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840