Protein Alignment CG3690 and SLC22A17

DIOPT Version :9

• Sequence 1: NP_001284764.1
• Gene: CG3690 / 31047
• FlyBaseID: FBgn0040350
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_065105.3
• Gene: SLC22A17 / 51310
• HGNCID: 23095
• Length: 649
• Species: Homo sapiens
• Alignment Length: 606
• Identity: 121/606 - (19%)
• Similarity: 214/606 - (35%)
• Gaps: 197/606 - (32%)

  Fly    23 PPQKEAAADFEAAIDAAGFGMFNILLLVAAVPAAMGTVYETSTMSYILPSAE------------- 74
            ||.   |:.:|...:|:|..:.: ..|.|:..:.:.|..:.|...:..|...
Human   132 PPN---ASGWEQPPNASGVSVAS-AALAASAASRVATSTDPSCSGFAPPDFNHCLKDWDYNGLPV 192

  Fly    75 ------------CDLKLSLLDKGILNAITYAGMISSAVLWGYLADIKGRRNLLIVGYAADTICVL 127
                        |||...::.:.||..:   |..|..:..||.||..|||.::::.......|.:
Human   193 LTTNAIGQWDLVCDLGWQVILEQILFIL---GFASGYLFLGYPADRFGRRGIVLLTLGLVGPCGV 254

  Fly   128 GGALSQSRIQLMVFKYLGGFCMSGPFAVLMTYLTELHGRKHRQRIMM-----MVGIMFSIATLTL 187
            |||.:.|...:|..::|.||.::|  ..|..||..|......||:.:     :||:......|
Human   255 GGAAAGSSTGVMALRFLLGFLLAG--VDLGVYLMRLELCDPTQRLRVALAGELVGVGGHFLFL-- 315

  Fly   188 PGLAMLILPETWNIQIWTLSLTSWQFFVAVTALPSLLSFVLFFFFP----ESPKFLMSKGRNREA 248
             |||::              ...|:|...:...|.:|  .||:.:|    ||.::|:.|.:..||
Human   316 -GLALV--------------SKDWRFLQRMITAPCIL--FLFYGWPGLFLESARWLIVKRQIEEA 363

  Fly   249 LDAFKFMYHLNSRKPKDSFPIKLLANEVIVPVKKHAKDETIPTELKLPTECVE-VQDPENQDSKK 312
            ....:.:...|                     :.|.:        .|..|..| :||.||.
Human   364 QSVLRILAERN---------------------RPHGQ--------MLGEEAQEALQDLENT---- 395

  Fly   313 SSLRSGFTQLRPLFTKPYLGLSLWVYLLNFCVLLGQNTMRLWLPQLFASINEYEN-----LMSGE 372
                                          |.|...::..      |||:..|.|     |:.|
Human   396 ------------------------------CPLPATSSFS------FASLLNYRNIWKNLLILG- 423

  Fly   373 SQSTSICNILEYSVNRTQSQLEAVTRNDPTVECHVII----TPST-YTNNLIVAGAGFVAYMLAG 432
                 ..|.:.:::.                .|:..:    :||. |..:|:.:|...:|.:..|
Human   424 -----FTNFIAHAIR----------------HCYQPVGGGGSPSDFYLCSLLASGTAALACVFLG 467

  Fly   433 FLVNLVGVKLIMTSGLL---IAAGCSIGMY----------W----------SSSAASTVALASLF 474
            ..|:..|.:.|:...:.   ||:...:|::          |          :.:|.:|.::..||
Human   468 VTVDRFGRRGILLLSMTLTGIASLVLLGLWDCEHPIFPTVWAQQGNPNRDLNEAAITTFSVLGLF 532

  Fly   475 VTMGSISATSVISASVSLFPTSLRTMIVSLEMMFGRLGSLLGNIFFPAL---MGLGCVPPFLMIS 536
            .:..:...:::::|.|  .||::|...:.|.|..|.||.|.|    ||.   ||.|.....::::
Human   533 SSQAAAILSTLLAAEV--IPTTVRGRGLGLIMALGALGGLSG----PAQRLHMGHGAFLQHVVLA 591

  Fly   537 AFMLAGCFMAAFLPLKNKAAL 557
            |..|. |.::..|..:.|..|
Human   592 ACALL-CILSIMLLPETKRKL 611

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3690	NP_001284764.1	SP	42..549	CDD:273317	112/577 (19%)
		MFS	49..>195	CDD:119392	41/175 (23%)
		MFS	419..>550	CDD:119392	34/156 (22%)
SLC22A17	NP_065105.3	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153304
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930