DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3690 and CG12783

DIOPT Version :9

Sequence 1:	NP_001284764.1	Gene:	CG3690 / 31047	FlyBaseID:	FBgn0040350	Length:	558	Species:	Drosophila melanogaster
Sequence 2:	NP_001262644.2	Gene:	CG12783 / 42019	FlyBaseID:	FBgn0038448	Length:	493	Species:	Drosophila melanogaster

Alignment Length:	539	Identity:	125/539 - (23%)
Similarity:	219/539 - (40%)	Gaps:	68/539 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 FEAAIDAAGFGMFNILLLVAAVPAAMGTVYETSTMSYILPSAECDLKLSLLDKGILNAITYAGMI 96
            |::.::..|||..::...|......|.|:.||..|..|.|:|.|||:::......|.|..:.|:|
  Fly     4 FDSVMEDIGFGRVHLFATVTLGLLQMLTIQETMGMGIIGPAAVCDLRMNEAQLASLTAAGFMGII 68

  Fly    97 SSAVLWGYLADIKGRRNLLIVGYAADTICVLGGALSQSRIQLMVFKYLGGFCMSGPFAVLMTYLT 161
            .|:..|||:.|.||||..|:.......:|.|....:.:.....|.:::....::||..|..|||:
  Fly    69 CSSYFWGYITDKKGRRWTLLRTITISNLCSLASMFTVTFTGFFVMRFITCIFVAGPSFVAATYLS 133

  Fly   162 ELHGRKHRQRIMMMVGIMFSIATLTLPGLAMLILP----ETWNIQIWTLSLTSWQFFVAVTALPS 222
            |....:...|.:..:.:....|.::.|..|.|.|.    |.....:.:|:|..|:....:..||.
  Fly   134 EFCSHRIMVRSITHLYMFTGFAMISCPAWATLFLSSGLIEFEEKLVGSLTLRPWRVLGCLYILPG 198

  Fly   223 LLSFVLFFFFPESPKFLMSKGRNREALDAFKFMYHLNSRKPKDSFPIK-LLANEVIVPVKKHAKD 286
            :::|:|....|||||||:..|..:..||..:::...|:.:......:| |||.:..|.||:..:.
  Fly   199 VVAFLLLLLLPESPKFLLMIGETKRGLDTMEWISRKNTGRTLSEDQMKRLLAYQEHVQVKRRKEH 263

  Fly   287 ETIPTELKLPTECVEVQDPENQDSKKSSLRSGFTQLRPLFTKPYLGLSLWVYLLNFCVLLGQNTM 351
            :..                         .||......||..|||.|....|.::.|.:.|..:.:
  Fly   264 QNF-------------------------FRSMLDDAMPLVRKPYGGYFTCVCMVMFVLGLLTHGL 303

  Fly   352 RLWLPQLFASINEYENLMSGESQSTSICNILEYSVNRTQSQLEAVTRNDPTVECHVIITPSTYTN 416
            .:|    :.::....|:..|.:...:.|.:|  .|..|...:|  |.:|..|.|....  ..:.:
  Fly   304 GIW----YTAMRNRCNMRQGNTNGMTFCQVL--FVPETGPFIE--TESDLDVVCSDSF--KGFND 358

  Fly   417 NLIVAGAGFVAYMLAGFLVNLVGVKLIMTSGLLIAAGCSIGMYWSSSAASTVALASLFVTMGSIS 481
            :.::.....|.|.::...:..|..|::....|:              |:||.....:|.|...:.
  Fly   359 SFVLGFVYVVLYNISWASLFCVHKKVMFVFSLV--------------ASSTFGFLLIFATNHMLQ 409

  Fly   482 ATSVI-------------SASVSLF-PTSLRTMIVSLEMMFGRLGSLLGNIFFPALMGLGCVPPF 532
            ..|::             ..|:.:| ||.||...:.:.:|:.|.|:..|.:...:.:...|....
  Fly   410 LFSLVFLIAFPGIIIGLLGGSLLVFVPTYLRGKALCISLMWCRCGAAFGAMLVGSKIQYNCELFL 474

  Fly   533 LMISAFMLAGCFMAAFLPL 551
            |.||...|....|..:|||
  Fly   475 LAISILPLIAACMEGYLPL 493

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3690	NP_001284764.1	SP	42..549	CDD:273317	119/525 (23%)
		MFS	49..>195	CDD:119392	41/145 (28%)
		MFS	419..>550	CDD:119392	27/144 (19%)
CG12783	NP_001262644.2	synapt_SV2	<2..>310	CDD:130366	84/334 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458192
Domainoid	1	1.000	45	1.000	Domainoid score	I3556
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	108	1.000	Inparanoid score	I296
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D724235at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	6.000