DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3690 and CG14691

DIOPT Version :9

Sequence 1:	NP_001284764.1	Gene:	CG3690 / 31047	FlyBaseID:	FBgn0040350	Length:	558	Species:	Drosophila melanogaster
Sequence 2:	NP_650012.2	Gene:	CG14691 / 41287	FlyBaseID:	FBgn0037829	Length:	522	Species:	Drosophila melanogaster

Alignment Length:	535	Identity:	218/535 - (40%)
Similarity:	328/535 - (61%)	Gaps:	33/535 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 ADFEAAIDAAGFGMFNILLLVAAVPAAMGTVYETSTMSYILPSAECDLKLSLLDKGILNAITYAG 94
            ||||.||...|||:||:.:|.:|||.....|:..|.:||::|||||||.||::|||:|:|:||||
  Fly    13 ADFETAIAECGFGLFNVFILCSAVPCLTAMVFSASALSYVMPSAECDLDLSIVDKGMLHAVTYAG 77

  Fly    95 MISSAVLWGYLADIKGRRNLLIVGYAADTICVLGGALSQSRIQLMVFKYLGGFCMSGPFAVLMTY 159
            ||.|||.||::||..|||.:||.|...|...||..:|||:..|||.||:..|..:.|||||:::|
  Fly    78 MIISAVPWGFIADTIGRRPVLISGGWLDGFFVLCASLSQNTAQLMAFKFFDGLIICGPFAVVVSY 142

  Fly   160 LTELHGRKHRQRIMMMVGIMFSIATLTLPGLAMLILPETWNIQIWTLSLTSWQFFVAVTALPSLL 224
            |.|.||:|||..||:.||:..||.::.||.|:.|:||......:.::...:||.|:||::.||||
  Fly   143 LAEFHGKKHRPYIMLFVGLCVSIGSMILPLLSYLLLPVPILFTVSSMKFRTWQVFLAVSSAPSLL 207

  Fly   225 SFVLFFFFPESPKFLMSKGRNREALDAFKFMYHLNSRKPKDSFPIKLLANEVIVPVKKHAKDET- 288
            |..|..|.|||||||||:|..::|||:.:.:|.||.||.::|:|||.|.:.  .|.:....|.|
  Fly   208 SGFLHIFLPESPKFLMSQGNYKKALDSLQRIYKLNKRKSRESYPIKHLTDP--TPDRSDDLDGTG 270

  Fly   289 IPTELKLPTECVEVQDPENQDSKKSSLRSGFTQLRPLFTKPYLGLSLWVYLLNFCVLLGQNTMRL 353
            .|:.|:           |.....:|....||.||:|:|:.|||.:||.||.|:||.::..|::||
  Fly   271 RPSTLQ-----------ERFSRAQSKFIDGFKQLKPMFSSPYLAISLQVYCLHFCQIMCVNSVRL 324

  Fly   354 WLPQLFASINEYENLMSGESQSTSICNILEYSVNRTQSQLEAVTRNDPTVECHVIITPSTYTNNL 418
            ||||:||::|..:.|.:.:   ||:|.:||::.|     .:::...:..|||.:...|.:|.||:
  Fly   325 WLPQIFATMNAMDTLGAND---TSMCAVLEHNAN-----AKSMDEEEKRVECALHHDPDSYLNNI 381

  Fly   419 IVAGAGFVAYMLAGFLVNLVGVKLIMTSGLLIAAGCSI------GMYWSSSAASTVALASLFVTM 477
            .|||.|     |.|||:....::..:.|..::.....|      .:|:..::..|:.::::::||
  Fly   382 TVAGIG-----LVGFLIIFPLMRFQVVSNHILKVFLFICIFLVGSLYFVKTSLVTMMVSAVYLTM 441

  Fly   478 GSISATSVISASVSLFPTSLRTMIVSLEMMFGRLGSLLGNIFFPALMGLGCVPPFLMISAFMLAG 542
            ..|.||::|..||.:|||.:|||::.|.|.||||||:.||:..|..|.|.|:.|||.:.:.|...
  Fly   442 MGICATTIIGMSVVIFPTLMRTMVLLLIMTFGRLGSVSGNMLLPVFMQLSCLAPFLWLCSLMSIA 506

  Fly   543 CFMAAFLPLKNKAAL 557
            ...:.||.:.::.:|
  Fly   507 FLFSLFLKVDDEQSL 521

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3690	NP_001284764.1	SP	42..549	CDD:273317	207/513 (40%)
		MFS	49..>195	CDD:119392	76/145 (52%)
		MFS	419..>550	CDD:119392	45/136 (33%)
CG14691	NP_650012.2	MFS	30..>216	CDD:119392	90/185 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445401
Domainoid	1	1.000	77	1.000	Domainoid score	I3080
eggNOG	1	0.900	-	-		E33208_3BMGJ
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	108	1.000	Inparanoid score	I296
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D724235at2759
OrthoFinder	1	1.000	-	-		FOG0014384
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.900