DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3690 and CG4324

DIOPT Version :9

Sequence 1:	NP_001284764.1	Gene:	CG3690 / 31047	FlyBaseID:	FBgn0040350	Length:	558	Species:	Drosophila melanogaster
Sequence 2:	NP_001286807.1	Gene:	CG4324 / 37830	FlyBaseID:	FBgn0034956	Length:	478	Species:	Drosophila melanogaster

Alignment Length:	524	Identity:	114/524 - (21%)
Similarity:	198/524 - (37%)	Gaps:	101/524 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 EAAIDAAGFGMFNILLLVAAVPAAMGTVYETSTMSYILPSAECDLKLSLLDKGILNAITYAGMIS 97
            :.||:|.|||.|::.|.:......|....|.:.:|.:.||..|:..::...:..:..:.:.||:.
  Fly    43 QQAINAFGFGWFHVKLSLLVGLCWMSDSMEMAILSILGPSLFCEWNVTKFQQASVTTVVFLGMML 107

  Fly    98 SAVLWGYLADIKGRRNLLIVGYAADTICVLGGALSQ---SRIQLMVFKYLGGFCMSGPFAVLMTY 159
            |:..|..|::..||::.|.:   ...:.||...||.   |...|:..:.|.||.: |.....:|.
  Fly   108 SSSFWTQLSNRYGRKSALTL---FGVLLVLYSILSSVAPSYAWLLTLRGLVGFAI-GCVPQSVTL 168

  Fly   160 LTELHGRKHRQRIMMMVGIMFSIATLTLPGLAMLILPETWNIQIWTLSLTSWQFFVAVTALPSLL 224
            ..|....||:.:.::::...:::.......||:::.|           ...|:..:|::|.|.|:
  Fly   169 YAEFLPTKHKGKCVVLMDCFWALGACFEVVLALVVYP-----------YYGWRGLLALSATPLLI 222

  Fly   225 SFVLFFFFPESPKFLMSKGRNREALDAFKFMYHLNSRKPKDSFPIKLLANEVIVPVKKHAKDETI 289
            ..:|..:..||.::....|.|.:|:...:.:.|.|.|        .:|...::      |.||
  Fly   223 FTILSPWLSESARYYSYNGHNDKAIKVLEQIAHNNKR--------HMLMGRLM------ADDE-- 271

  Fly   290 PTELKLPTECVEVQDPENQDSKKSSLRSGFTQLRP-LFTKPYLGLSLWVYLLNFCVLLGQNTMRL 353
                   ..|.|            |.||   .|.| |:....|   ||.               |
  Fly   272 -------PSCAE------------SFRS---LLSPSLYRTTIL---LWF---------------L 296

  Fly   354 WLPQLFASINEYENLMSGESQSTSICNILEYSVNRTQSQLEAVTRNDPTVECHVIITPSTYTNNL 418
            ||...|.    |..|                 |..|...|.|..:.....||...:| |.:.:.|
  Fly   297 WLASAFC----YYGL-----------------VLVTTELLVARNKESHPNECVTFMT-SDFMDLL 339

  Fly   419 IVAGAGFVAYMLAGFLVNLVGVKLIMTSGLLIAAGCSIGMYWSSSAASTVALASLFVTMGSISA- 482
            .:..:.|...:|...:|.|.|.|..:....|....|::.:....|..||  ..:||:..|:||.
  Fly   340 WITLSEFPGILLTIKVVKLFGKKKTIVLQYLALVLCTLVLMSVESRFST--SVTLFIARGTISGI 402

  Fly   483 -TSVISASVSLFPTSLRTMIVSLEMMFGRLGSLLGNIFFPALMGLGCVPPFLMISAFMLAGCFMA 546
             .::...:..::|.:||::.||...:..|||::|.......||....:......:...|......
  Fly   403 FQAIYVYTPEIYPAALRSVGVSGCSVLARLGAMLTPFVAQVLMDSSRIQAMSTYAIVGLLASIAC 467

  Fly   547 AFLP 550
            .|||
  Fly   468 VFLP 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3690	NP_001284764.1	SP	42..549	CDD:273317	106/512 (21%)
		MFS	49..>195	CDD:119392	30/148 (20%)
		MFS	419..>550	CDD:119392	29/132 (22%)
CG4324	NP_001286807.1	2A0119	10..476	CDD:273328	114/524 (22%)
CG4324	NP_001286807.1	MFS	60..471	CDD:119392	104/505 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458124
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940