DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3690 and CG15221

DIOPT Version :9

Sequence 1:	NP_001284764.1	Gene:	CG3690 / 31047	FlyBaseID:	FBgn0040350	Length:	558	Species:	Drosophila melanogaster
Sequence 2:	NP_001096957.1	Gene:	CG15221 / 32127	FlyBaseID:	FBgn0030331	Length:	545	Species:	Drosophila melanogaster

Alignment Length:	567	Identity:	140/567 - (24%)
Similarity:	257/567 - (45%)	Gaps:	77/567 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 EPSESGDPKPHKTAEHQIGDPPQKEAAADFEAAIDAAGFGMFNILLLVAAVPAAMGTVYETSTMS 67
            |.:.|..|:||                 .||.||...|.|.|:..||:......||.:.|...:|
  Fly    22 EENLSEKPRPH-----------------TFEEAITLTGVGRFHYKLLLICGLCFMGVMVEIMGVS 69

  Fly    68 YILPSAECDLKLSLLDKGILNAITYAGMISSAVLWGYLADIKGRRNLLIVGYAADTICVLGGALS 132
            .|:...:|||:.:|..:|||.:..:.|::.|:...|:|||..||...|.......::|.:..|.|
  Fly    70 LIMNQMKCDLQPTLNQQGILASAGFLGVVLSSHAMGFLADTWGRATTLRYALCISSVCSIVSAFS 134

  Fly   133 QSRIQLMVFKYLGGFCMSGPFAVLMTYLTELHGRKHRQRIMMMVGIMFSIATLTLPGLAMLILPE 197
            .:...|:||::|.||.:||..|.:.:...|.||...|.|.:.::.....:|.:..|.:|:.|||
  Fly   135 VNIWMLIVFRFLTGFFISGGQACVFSLCGEFHGTGSRIRHVTLLSGFLCMAMIFAPAMAIGILP- 198

  Fly   198 TWNIQIWTLSL----TSWQFFVAVTALPSLLSFVLFFFFPESPKFLMSKGRNREALDAFKFMYHL 258
               ::|.|:.|    :||:..:.......||:.|.....||:||:|:.:||..|:|:..:.::..
  Fly   199 ---LRIETIVLGMHFSSWRVLLLANVSIPLLALVGISALPETPKYLLVQGRGDESLEVLRSIFAN 260

  Fly   259 NSRKPKDSFPIKLLANEVIVPVKKHAKDETIPTELKLPTECVEVQDPENQDSKKSSLRSGFTQLR 323
            ||.:....:|:|                     |:.|.:..|.:.|..   ....::|..:.|..
  Fly   261 NSGRDPSEYPVK---------------------EVALESGGVSLSDVH---GFLDAVRLVWHQTV 301

  Fly   324 PLFTKPYLGLSLWVYLLNFCVL------LGQNTMRLWLPQLFASINEYENLMSGESQSTSICNIL 382
            |||.:    ..|| :.||.|.:      |.|... :|.|.:.      :.|.:...::|.:|.:|
  Fly   302 PLFYR----ARLW-HTLNICCIQFIIYFLAQGIF-MWFPTIL------DELGTRNGENTLLCTVL 354

  Fly   383 E-YSVNRTQSQLEAVTRNDPTVECHVIITPSTYTNNLIVAGAGFVAYMLAGFLVNLVGVKLIMTS 446
            : :::|.:.        .|....|.|.:..|||...:|:|....|.|::..::::.:|.|.::.:
  Fly   355 QGFNINSSS--------EDEASSCSVEVDTSTYQVMIIIAACFVVIYLIFAYIIDYMGKKNLLMA 411

  Fly   447 GLLIAAGCSIGMYWSSSAASTVALASLFVTMGSISATSVISASVSLFPTSLRTMIVSLEMMFGRL 511
            .:::...|.:.:::....|..|...::.:.:|:.... |.:.::..:||.:..|.:...||.|||
  Fly   412 WMVLTMICLVALHYVEQFALVVIALTVVMAIGNCGGL-VSTIAMEFYPTHINAMGMCFIMMVGRL 475

  Fly   512 GSLLGNIFFPALMGLGCVPPFLMISAFMLAGCFMAAFLPLKNKAALK 558
            |:::|:.....|:...|.|.|..:.|.::..|.:..|||.|.::..|
  Fly   476 GAVVGSNILGRLLFASCDPIFWALLALVVLLCTLGYFLPEKARSQQK 522

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3690	NP_001284764.1	SP	42..549	CDD:273317	125/517 (24%)
		MFS	49..>195	CDD:119392	42/145 (29%)
		MFS	419..>550	CDD:119392	28/130 (22%)
CG15221	NP_001096957.1	2A0115	36..488	CDD:273327	122/500 (24%)
CG15221	NP_001096957.1	MFS	51..488	CDD:119392	116/485 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458195
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	108	1.000	Inparanoid score	I296
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D724235at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1117
	6	6.000