DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3690 and CG31106

DIOPT Version :9

Sequence 1:	NP_001284764.1	Gene:	CG3690 / 31047	FlyBaseID:	FBgn0040350	Length:	558	Species:	Drosophila melanogaster
Sequence 2:	NP_733086.2	Gene:	CG31106 / 318594	FlyBaseID:	FBgn0051106	Length:	513	Species:	Drosophila melanogaster

Alignment Length:	575	Identity:	154/575 - (26%)
Similarity:	250/575 - (43%)	Gaps:	92/575 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 SESG----DPKPHKTAEHQIGDPPQKEAAADFEAAIDAAGFGMFNILLLVAAVPAAMGTVYETST 65
            ||||    :.|| |:|.       ...|..::|..:...|||....::|.||....|..:.||..
  Fly     3 SESGQQDVESKP-KSAR-------STSAGHEYEDVLQIIGFGRVQWIVLFAAGLLLMMVINETMG 59

  Fly    66 MSYILPSAECDLKLSLLDKGILNAITYAGMISSAVLWGYLADIKGRRNLLIVGYAADTICVLGGA 130
            ||||...::||.:::.:||.:::|.::.|:..|:..||||:|..|||.:||  |..    :.|..
  Fly    60 MSYITIVSQCDFEMNSMDKAVMSAASFIGIFCSSYFWGYLSDTIGRRPVLI--YTT----IAGNF 118

  Fly   131 LSQ-----SRIQLMVFKYLG-GFCMSGPFAVLMTYLTELHGRKHRQRIMMMVGIMFSIATLTLPG 189
            ||.     ....|.||...| ||.::|..:....||.|....:||...:....:...::|:.:|.
  Fly   119 LSLCSTVIPNYWLYVFIRFGVGFFIAGASSTTYAYLGEFFTPRHRPIAINYASLFVGVSTVYVPA 183

  Fly   190 LAMLILPETWNIQIWT-LSLTSWQFFVAVTALPSLLSFVLFFFFPESPKFLMSKGRNREALDAFK 253
            .|.|||...|::.|.. .||..|:.......||.::..::.:..|||||.|||..:..||..|..
  Fly   184 TAWLILSMDWSVSITDGFSLRPWRLLTICYLLPGVVGTLMLWSLPESPKILMSLHKTEEAFAAVD 248

  Fly   254 FMYHLNSRKPKDSFPIKLLANEVIVPVKKHAKDETIPTELKLPTECVEVQDPENQDSKKSSLRSG 318
            ::...||.|....|             |.|          ||.||     |..|.::.....:|.
  Fly   249 WIAVTNSGKHLHEF-------------KVH----------KLKTE-----DNANGENILLISKSA 285

  Fly   319 FTQLR-------PLFTKPYLGLSLWVYLLNF---CVLL-----GQNTMRLWLPQLFASINEYENL 368
            ||.::       ||..:|        :||||   |.::     ..:.|.||.|       |.:|.
  Fly   286 FTTIKKMWKETLPLLRRP--------HLLNFVISCTIMCGLFFSSSGMGLWYP-------EIQNR 335

  Fly   369 MSGES--QSTSICNILEYSVNRTQSQLEAVTRNDPTVECHVIITPSTYTNNLIVAGAGFVAYMLA 431
            :...:  .|.::|.:::.|:::.|:       |.....|...|...:|.:.:....|..|.|:|.
  Fly   336 LGSNAADDSMTVCQVIDASIDQMQA-------NASNKICDDHINTKSYIDTITYGSALIVGYILM 393

  Fly   432 GFLVNLVGVKLIMTSGLLIAAGCSIGMYWSSSAASTVALASLFVTMGSISATSVISASVSLFPTS 496
            |.::|.:|.|..::.||.:|..|:|.:.:.....:.|....|::.:..:..:.:..|.|.|.||.
  Fly   394 GLVINTIGRKASISIGLTLAGACAIALIFIKDEVAIVVCFCLYLVLPGLCVSILSGAVVDLVPTH 458

  Fly   497 LRTMIVSLEMMFGRLGSLLGNIFFPALMGLGCVPPFLMISAFMLAGCFMAAFLPL 551
            ||...|.:.:|.||.||:.|:.....|:...|...|.:.|.|:|....:...||:
  Fly   459 LRGKAVCICLMLGRTGSVFGSNIIGVLLESYCSLTFGVFSGFVLVCASLTLLLPI 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3690	NP_001284764.1	SP	42..549	CDD:273317	140/530 (26%)
		MFS	49..>195	CDD:119392	47/151 (31%)
		MFS	419..>550	CDD:119392	35/130 (27%)
CG31106	NP_733086.2	2A0115	37..486	CDD:273327	133/504 (26%)
CG31106	NP_733086.2	MFS	40..512	CDD:119392	139/527 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458186
Domainoid	1	1.000	77	1.000	Domainoid score	I3080
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	108	1.000	Inparanoid score	I296
Isobase	1	0.950	-	0	Normalized mean entropy	S5645
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D724235at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1117
	8	7.950